ChemicalBook > CAS DataBase List > 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
- Product Name
- 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
- CAS No.
- 2163772-16-3
- Chemical Name
- 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
- Synonyms
- DBCO-PEG3-NHS ester;DBCO-NH-PEG3-CH2CH2COONHS;2,5-Dioxo-1-pyrrolidinyl 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-4,7,10-trioxa-13-azaheptadecanoate;4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB59382656
- Molecular Formula
- C32H35N3O9
- Formula Weight
- 605.64
- MOL File
- 2163772-16-3.mol
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4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester Property
- Density
- 1.35±0.1 g/cm3(Predicted)
- pka
- 15.14±0.46(Predicted)
- form
- Solid-Liquid Mixture
- color
- Off-white to light yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
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4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester Chemical Properties,Usage,Production
Uses
DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
[2] Shih-Hsien Chuang, et al. Antibody-drug conjugates containing an anti-mesothelin antibody and uses thereof. Patent. WO2021248048.
4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester Suppliers
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View Lastest Price from 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester manufacturers
XIAMEN SINOPEG BIOTECH CO., LTD.
- Product
- DBCO-PEG3-NHS 2163772-16-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-04
Xian confluore Biological Technology Co., Ltd.
- Product
- DBCO-PEG3-NHS ester 2163772-16-3
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >99.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-20
2163772-16-3, 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl esterRelated Search:
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