DBCO-PEG4-SE

Product Name: DBCO-PEG4-SE
CAS No.: 1427004-19-0
Chemical Name: DBCO-PEG4-SE
Synonyms: DBCO-PEG4-SE;DBCO-PEG4-NHS;DBCO-PEG4-SPA;DBCO-PEG4-NHS easer;DBCO-PEG4-NHS ester;DBCO-CONH-PEG4-NHS ester;DBCO-PEG4-succinimidyl ester;Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester;inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers;2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate
CBNumber: CB22984375
Molecular Formula: C34H39N3O10
Formula Weight: 649.69
MOL File: 1427004-19-0.mol

More

Less

DBCO-PEG4-SE Property

Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
pka: 15.14±0.46(Predicted)
form: gel or oil
color: Colourless to yellow
InChI: InChI=1S/C34H39N3O10/c38-30(11-12-31(39)36-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)36)35-16-18-44-20-22-46-24-23-45-21-19-43-17-15-34(42)47-37-32(40)13-14-33(37)41/h1-8H,11-25H2,(H,35,38)
InChIKey: RRCXYKNJTKJNTD-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O

More

Less

Safety

WGK Germany: 3
HS Code: 2942000090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 764019
Product name: Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester
Purity: 95%
Packaging: 1MG
Price: $37
Updated: 2023/06/20

Sigma-Aldrich

Product number: 764019
Product name: Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester
Purity: 95%
Packaging: 5MG
Price: $118
Updated: 2023/06/20

Sigma-Aldrich

Product number: 764019
Product name: Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester
Purity: 95%
Packaging: 50MG
Price: $510
Updated: 2023/06/20

TRC

Product number: D195020
Product name: DBCO-PEG4-NHSEster
Packaging: 1mg
Price: $45
Updated: 2021/12/16

Chem-Impex

Product number: 35051
Product name: DBCO-PEG4-NHSester,95%
Purity: 95%
Packaging: 5MG
Price: $56
Updated: 2021/12/16

More

Less

DBCO-PEG4-SE Chemical Properties,Usage,Production

Description

DBCO-PEG4-NHS Ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

Protein-peptide conjugates
Antibody-enzyme or antibody-drug conjugates
Protein or peptide-oligonucleotide conjugates
Surface modification

DBCO-PEG4-SE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DBCO-PEG4-SE Suppliers

China 66 United Kingdom 1 United States 6 Global 73

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 029-86217788 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1992
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4824
Advantage: 58

Shanghai Jiyi Biological Technology Co., LTD

Tel: 021-54135696 18516235431
Fax: 50815371
Email: shgegenetech@163.com
Country: China
ProdList: 986
Advantage: 55

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-50266790 Q3382968513
Fax: QQ3382968513
Email: Hailey@shsendpharm.com
Country: China
ProdList: 3151
Advantage: 55

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 4109
Advantage: 55

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1246
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6357
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 9859
Advantage: 58

More

Less

View Lastest Price from DBCO-PEG4-SE manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-PEG4-NHS ester 1427004-19-0
Price: US $0.00/mg
Min. Order: 50mg
Purity: >99.00%
Supply Ability: 250
Release date: 2024-03-20

1427004-19-0, DBCO-PEG4-SERelated Search:

Diazo Biotin-PEG3-DBCO PC DBCO-PEG3-Biotin Desthiobiotin-PEG4-DBCO 2-(4-Ethyl-1-piperazinyl)-4-[4-(4-ethyl-1-piperazinyl)phenyl]-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine DBCO-amine DBCO-NHS Ester DBCO-sulfo-NHS ester DBCO-C6-NHS ester DBCO-PEG4-Acid DBCO-PEG4-biotin DBCO-PEG4-Benzylamine DBCO-PEG4-Val-Cit-PAB-PNP DBCO-PEG4-maleimide DBCO-PEG4-DBCO DBCO-PEG4-amine DBCO-SE DBCO-PEG5-NHS ester

DBCO-PEG4-NHS ester

DBCO-PEG4-SE

DBCO-PEG4-succinimidyl ester

Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester

DBCO-CONH-PEG4-NHS ester

2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate

4,7,10,13-Tetraoxa-16-azaeicosanoic acid, 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester

DBCO-PEG4-SPA

DBCO-PEG4-NHS

inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers

DBCO-PEG4-NHS easer

1427004-19-0

peg

ADC-Linkers