ChemicalBook > CAS DataBase List > DBCO-maleimide
DBCO-maleimide
- Product Name
- DBCO-maleimide
- CAS No.
- 1395786-30-7
- Chemical Name
- DBCO-maleimide
- Synonyms
- Dibenzocyclooctyne-maleimide;DBCO-MAL;DBCO-maleimide;DBCO-Maleimide,Dibenzocyclooctyne-maleimide;DBCO-maleimide (This product is unavailable in the U.S.);DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5);Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.);1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-;N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide;N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
- CBNumber
- CB92985649
- Molecular Formula
- C25H21N3O4
- Formula Weight
- 427.45
- MOL File
- 1395786-30-7.mol
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DBCO-maleimide Property
- Melting point:
- 162 °C
- Boiling point:
- 790.5±60.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Solid
- pka
- 15.03±0.46(Predicted)
- color
- Off-white to Gray
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 760668
- Product name
- Dibenzocyclooctyne-maleimide
- Purity
- for Copper-free Click Chemistry
- Packaging
- 1MG
- Price
- $32.8
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 760668
- Product name
- Dibenzocyclooctyne-maleimide
- Purity
- for Copper-free Click Chemistry
- Packaging
- 5MG
- Price
- $101
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 760668
- Product name
- Dibenzocyclooctyne-maleimide
- Purity
- for Copper-free Click Chemistry
- Packaging
- 50MG
- Price
- $393
- Updated
- 2023/06/20
TRC
- Product number
- A939575
- Product name
- Dbco-Maleimide
- Packaging
- 1mg
- Price
- $40
- Updated
- 2021/12/16
Chem-Impex
- Product number
- 35063
- Product name
- DBCOmaleimide,95%(HPLC)
- Purity
- 95%(HPLC)
- Packaging
- 5MG
- Price
- $56
- Updated
- 2021/12/16
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DBCO-maleimide Chemical Properties,Usage,Production
Description
DBCO-Maleimide is a sulfhydryl reactive reagent containing a maleimide group and a DBCO moiety. Maleimide group specifically and efficiently reacts with thiols to form thioether bonds. The low mass weight will add minimal spacer to modified molecules and will enable simple and efficient incorporation of DBCO moiety into cysteine-containing peptides or other thiol-containing biomolecules. DBCO is commonly used for copper-free Click Chemistry reactions.
Uses
Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Applications Include:
- Protein-peptide conjugates
- Antibody-enzyme or antibody-drug conjugates
- Protein or peptide-oligonucleotide conjugates
- Surface modification
Uses
Dbco-Maleimide is used in preparation of radioactive metal indicator-chelating peptide derivative-conjugated antibodies for medical imaging.
DBCO-maleimide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DBCO-maleimide manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- DBCO-Maleimide 1395786-30-7
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >98.00%
- Supply Ability
- 250
- Release date
- 2024-03-20
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