ChemicalBook > CAS DataBase List > 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE

2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE

Product Name
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
CAS No.
13096-62-3
Chemical Name
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
Synonyms
2,3,4,6-tetra-O-benzyl-D-glucopyranolactone;5-lactone;Tetra-O-benzyl-δ-D-Gluconolactone;2,3,4,6-Tetra-O-benzyl-D-glucono-1;Tetra-O -benzyl-delta-D-Gluconolactone;2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE;2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lacton;2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lactone;2,3,4,6-Tetrakis-O-benzyl-D-glucono-1,5-lactone;2,3,4,6-Tetra-O-benzyl-D-gluconic acid-δ-lactone
CBNumber
CB4849469
Molecular Formula
C34H34O6
Formula Weight
538.63
MOL File
13096-62-3.mol
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2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Property

Boiling point:
677.7±55.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
InChIKey
BUBVLQDEIIUIQG-ORMLBLSRNA-N
SMILES
[C@H]1(OCC2=CC=CC=C2)C(=O)O[C@H](COCC2C=CC=CC=2)[C@@H](OCC2=CC=CC=C2)[C@@H]1OCC1=CC=CC=C1 |&1:0,12,22,31,r|
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Safety

Hazard Codes 
Xn
Risk Statements 
22
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3793
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
1G
Price
$125
Updated
2025/07/31
TRC
Product number
T289210
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
1mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
294761
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
1g
Price
$460
Updated
2021/12/16
TRC
Product number
T289210
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
10mg
Price
$1175
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0092465
Product name
2,3,4,6-TETRAKIS-O-(PHENYLMETHYL)-D-GLUCONIC ACID LACTONE
Purity
95.00%
Packaging
5G
Price
$1848
Updated
2021/12/16
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2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Chemical Properties,Usage,Production

Uses

2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone is used as a reactant to synthesize various glucoside containing compounds as selective SGLT2 inhibitors for the treatment of type 2 diabetes mellitus.

Synthesis

6564-72-3

13096-62-3

Example XXI Synthesis of 2,3,4,6-tetra-O-benzyl-D-glucopyranoside: 4 g of freshly activated 4? molecular sieves and 3.3 g of N-methylmorpholine-N-oxide were added to a 140 mL solution of dichloromethane containing 10.0 g of 2,3,4,6-tetra-O-benzyl-α-D-glucopyranose. After stirring the reaction mixture for 20 minutes at room temperature, 0.3 g of tetrapropylammonium perruthenate was added. Stirring was continued at room temperature for 2 h. Upon completion of the reaction, the reaction solution was diluted with dichloromethane and filtered through a diatomaceous earth pad. The filtrate was washed sequentially with aqueous sodium thiosulfate and deionized water and dried over anhydrous sodium sulfate. After concentration under reduced pressure to remove the solvent, the residue was purified by silica gel column chromatography (eluent: cyclohexane/ethyl acetate, 4:1, v/v). The product was obtained as 8.2 g in 82% yield. Mass spectrum (ESI+): m/z = 539 [M + H]+.

References

[1] Patent: WO2005/92877, 2005, A1. Location in patent: Page/Page column 63
[2] Patent: US2006/189548, 2006, A1. Location in patent: Page/Page column 26-27
[3] Patent: US2006/234953, 2006, A1. Location in patent: Page/Page column 14
[4] Patent: US2007/4648, 2007, A1. Location in patent: Page/Page column 14
[5] Patent: US2007/27092, 2007, A1. Location in patent: Page/Page column 26

2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Suppliers

Shanghai XueEr Pharmaceutical Technology Co., Ltd
Tel
021-34622192 13917187091
Fax
86-21-34622765
Email
1021708276@qq.com
Country
China
ProdList
81
Advantage
57
Jinan Samuel Pharmaceutical Co., Ltd.
Tel
0531-88821801 15192360884
Fax
0531-88821802
Email
605818151@qq.com
Country
China
ProdList
417
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
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View Lastest Price from 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE 13096-62-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
2000
Release date
2025-06-05
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone 13096-62-3
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-14
Jinan Shengqi pharmaceutical Co,Ltd
Product
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE 13096-62-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10MT
Release date
2019-03-21

13096-62-3, 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONERelated Search:


  • 2,3,4,6-TETRAKIS-O-(PHENYLMETHYL)-D-GLUCONIC ACID LACTONE
  • 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
  • 5-lactone
  • D-Gluconic acid,2,3,4,6-tetrakis-O-(phenylMethyl)-, d-lactone
  • D-Gluconic acid, 2,3,4,6-tetrakis-O-(phenylMethyl)-, δ-lactone
  • 2,3,4,6-Tetrakis-O-(phenylmethyl)-D-Gluconic Acid, D-Lactone
  • 2,3,4,6-Tetra-O-benzyl-D-glucono-1
  • 2,3,4,6-tetra-O-benzyl-D-glucopyranolactone
  • (3R,4S,5R,6R)-3,4,5-Tris(benzyloxy)-6-(benzyloxymethyl)tetrahydropyran-2-one
  • 2,3,4,6-Tetra-O-benzyl-D-gluconic acid-δ-lactone
  • (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]oxan-2-one
  • 2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lacton
  • Tetra-O -benzyl-delta-D-Gluconolactone
  • 2,3,4,6-Tetrakis-o-(phenylmethyl)-D-gluconic acid delta-lactone
  • (3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-one
  • 2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lactone
  • TIANFUCHEM--13096-62-3--High purity 6-Methylpyridine-3-carboxylic acid factory price
  • 2,3,4,6-Tetrakis-O-benzyl-D-glucono-1,5-lactone
  • Tetra-O-benzyl-δ-D-Gluconolactone
  • 2,3,4,6-tetra-O-Benzyl-D-glucono-1,5-lactone 95%
  • 13096-62-3
  • C34H34O6
  • Pharmaceutical Intermediates