Thiophene-2-ethylamine

Product Name: Thiophene-2-ethylamine
CAS No.: 30433-91-1
Chemical Name: Thiophene-2-ethylamine
Synonyms: 2-(thiophen-2-yl)ethan-1-aMine;2-THIOPHENEETHYLAMINE;2-(2-AMINOETHYL)THIOPHENE;2-Thien-2-yL;ThiopheneEthaMine;RARECHEM AL BW 0099;2-Thiopheneethamine;2-Thiopheneethylamin;2-ThiophenethylaMine;THIOPHENE ETHYLAMINE
CBNumber: CB4853460
Molecular Formula: C6H9NS
Formula Weight: 127.21
MOL File: 30433-91-1.mol

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Thiophene-2-ethylamine Property

Melting point:: 202 °C
Boiling point:: 200-201 °C/750 mmHg (lit.)
Density: 1.087 g/mL at 25 °C (lit.)
refractive index: n20/D 1.551(lit.)
Flash point:: 190 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO, Methanol
pka: 9.47±0.10(Predicted)
form: Liquid
Specific Gravity: 1.087
color: Colorless to yellow
Sensitive: Air Sensitive
BRN: 106962
InChI: 1S/C6H9NS/c7-4-3-6-2-1-5-8-6/h1-2,5H,3-4,7H2
InChIKey: HVLUYXIJZLDNIS-UHFFFAOYSA-N
SMILES: NCCc1cccs1
CAS DataBase Reference: 30433-91-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36-37/39
RIDADR: NA 1993 / PGIII
WGK Germany: 3
HazardClass: IRRITANT
HazardClass: 8
PackingGroup: II
HS Code: 29339900
Storage Class: 10 - Combustible liquids
Hazard Classifications: Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 423270
Product name: 2-Thiopheneethylamine
Purity: 96%
Packaging: 1g
Price: $29.35
Updated: 2025/07/31

Sigma-Aldrich

Product number: 423270
Product name: 2-Thiopheneethylamine
Purity: 96%
Packaging: 5g
Price: $145.35
Updated: 2025/07/31

TCI Chemical

Product number: A1637
Product name: 2-(2-Aminoethyl)thiophene
Purity: >98.0%(GC)
Packaging: 25g
Price: $68
Updated: 2025/07/31

TCI Chemical

Product number: A1637
Product name: 2-(2-Aminoethyl)thiophene
Purity: >98.0%(GC)
Packaging: 250g
Price: $426
Updated: 2025/07/31

TCI Chemical

Product number: A1637
Product name: 2-(2-Aminoethyl)thiophene
Purity: >98.0%(GC)
Packaging: 5g
Price: $25
Updated: 2025/07/31

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Thiophene-2-ethylamine Chemical Properties,Usage,Production

Chemical Properties

A colorless to yellow liquid with unstable properties requiring protection with nitrogen gas. It appears as a light yellow clear liquid, but turns red upon prolonged exposure.

Uses

[2-(Thiophene-2-yl)ethyl]amine is used in the synthesis of geldanamycin derivatives as HCV replication inhibitors targetting Hsp90.

Uses

2-Thiopheneethylamine (2-thiophene ethyl amine, 2-(thien-2-yl)ethylamine) is suitable to functionalize multiwall carbon nanotubes (MWCNT).
It may be used as a reactant in the synthesis of pyrimidine derivatives by reacting with various isothiocyanatoketones and acylguanidines derivatives by reacting with aroyl S-methylisothiourea.

General Description

2-Thiopheneethylamine (2-(thiophen-2-yl)ethanamine) is an aromatic amine. It undergoes microwave induced condensation with iminodiacetic acid to form the corresponding piperazine-2,6-dione derivatives. Its effect as a probable substitute to the pyridine ligand on the performance of poly(3-hexylthiophene)/CdSe hybrid solar cells has been investigated.

Synthesis

N,N-Dimethylformamide (DMF) reacts with thiophene to obtain 2-thiophenecarbaldehyde, then reacts with isopropyl chloroacetate to obtain 2-thiopheneacetaldehyde, and then reacts with hydroxylamine hydrochloride to obtain 2-thiopheneacetaldehyde oxime, and finally reduced to give 2-thiopheneethylamine.

References

[1] M. BARWIOLEK. Structural and spectral studies of silver(I) complexes with new Schiff bases derived from 2-thiopheneethylamine and their application in thin layer deposition by spin and dip coating techniques[J]. Polyhedron, 2017, 124: Pages 12-21. DOI:10.1016/j.poly.2016.12.011.
[2] BHUSHAN D. VARPE S B J. Schiff Base of Isatin with 2-Thiopheneethylamine and Its Mannich Bases: Synthesis, Docking, and In Vitro Anti-Inflammatory and Antitubercular Activity[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 2: 372-379. DOI:10.1134/S1068162022020030.
[3] JUN YAN LEK. Understanding the Effect of Surface Chemistry on Charge Generation and Transport in Poly (3-hexylthiophene)/CdSe Hybrid Solar Cells[J]. ACS Applied Materials & Interfaces, 2011, 3 2: 287-292. DOI:10.1021/am100938f.
[4] SANDEEP KUMAR. Efficient synthesis of piperazine-2,6-dione and 4-(1H-indole-2-carbonyl)piperazine-2,6-dione derivatives and their evaluation for anticancer activity[J]. Medicinal Chemistry Research, 2013, 22 10: 4600-4609. DOI:10.1007/s00044-012-0438-7.

Thiophene-2-ethylamine Preparation Products And Raw materials

Raw materials

2-Thiophenecarboxaldehyde Nitromethane Potassium hydroxide Acetaldoxime Chlorotrimethylsilane Tetrahydrofuran Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Isopropyl chloroacetate Lithium borohydride

Preparation Products

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride 5-(2-AMINOETHYL)THIOPHENE-2-SULFONAMIDE

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Thiophene-2-ethylamine Suppliers

Americas 1 Belgium 2 Canada 1 China 331 Europe 4 Germany 5 India 11 Japan 2 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 12 United States 37 Global 414

J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
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INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
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3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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Country: China
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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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Capot Chemical Co., Ltd

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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View Lastest Price from Thiophene-2-ethylamine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Thiophene-2-ethylamine 30433-91-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98
Supply Ability: 10000KGS
Release date: 2026-01-04

Henan Aochuang Chemical Co.,Ltd.

Product: Thiophene-2-ethylamine 30433-91-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-13

Hebei Yanxi Chemical Co., Ltd.

Product: 2-Thiopheneethylamine 30433-91-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2023-09-18

30433-91-1, Thiophene-2-ethylamineRelated Search:

3-Cyanomethylthiophene 2-Thiophenemethylamine 2-Thiophenecarboxaldehyde 2-Thiopheneacetic acid Thiophenethiol 2-Thiophenecarboxylic acid Ethylamine 3-Thiopheneacetic acid Tetrahydrothiophene Cephalothin sodium Thiophene Thifensulfuron methyl 2-Thiophenemethanol Dibenzothiophene Ticlopidine hydrochloride 2-PYRIDIN-3-YL-AZEPANE D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride 4-(4-CHLOROPHENYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE

20(2-thienyl)ethylamine

2-(2'-Thienyl) ethyl amine/ Thiophene-2-ethylamine

2-(2-Aminoethyl)thiophene~Thiophene-2-ethylamine

2-Thiopheneethylamin

Thiophene-2-Ethylamine ,99%

2-(2-Thienyl)ethanamine

2-Thiopheneethanamine

Thiophene-2-ethanamine

Thiophene-2-ethylamine,98%

2-Thiophen-2-ylethanamine

2-(2-thienyl)ethanamine(SALTDATA: FREE)

2-ThiophenethylaMine

2-(Thien-2-yl)ethylamine

2-(thiophen-2-yl)ethan-1-aMine

ThiopheneEthaMine

[2-(Thiophene-2-yl)ethyl]aMine

THIOPHENE ETHYLAMINE

THIOPHENE-2-ETHYLAMINE

THIOPHENE-2-ETHYLAMINE HCL SALT

RARECHEM AL BW 0099

2-(2-AMINOETHYL)THIOPHENE

2-(2'-THIENYL)ETHYL AMINE

2-(2-THIENYL)ETHYLAMINE

2-(2-THIENYL)-1-ETHANAMINE

2-(2-THIENYL)-1-ETHANAMINE HYDROCHLORIDE

2-AMINOETHYLTHIOPHENE

2-THIOPHENEETHYLAMINE

B-2-THIENYLETHYLAMINE

.beta.-2-Thienylethylamine

Thiophen-2-ylacetyl chloride

2-Thiopheneethamine

2-(2-Aminoethyl)thiophene &gt

2-Thien-2-yL

Thiophene-2-ethylamine ISO 9001：2015 REACH

2-(Thiophen-2-yl)ethylamine

Rotigotine Impurity 17

2-Thiopheneethylamine, 96%

30433-91-1

423-27-0

30433-14-3

8349-17-0

C6H9SN

AMINE

Building Blocks

Heterocyclic Building Blocks

Thiophenes

Building Blocks

C4 to C6

Chemical Synthesis

Heterocyclic Building Blocks

Building Blocks

Heterocyclic Building Blocks

Thiophenes

Amines

Heterocyclic Compounds

Ticlopidine Clopidogrel

Anilines, Aromatic Amines and Nitro Compounds

Thiophene&Benzothiophene