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Thiophene-2-ethylamine

Product Name
Thiophene-2-ethylamine
CAS No.
30433-91-1
Chemical Name
Thiophene-2-ethylamine
Synonyms
2-(thiophen-2-yl)ethan-1-aMine;2-THIOPHENEETHYLAMINE;2-(2-AMINOETHYL)THIOPHENE;2-Thien-2-yL;ThiopheneEthaMine;RARECHEM AL BW 0099;2-Thiopheneethamine;2-Thiopheneethylamin;2-ThiophenethylaMine;THIOPHENE ETHYLAMINE
CBNumber
CB4853460
Molecular Formula
C6H9NS
Formula Weight
127.21
MOL File
30433-91-1.mol
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Thiophene-2-ethylamine Property

Melting point:
202 °C
Boiling point:
200-201 °C/750 mmHg (lit.)
Density 
1.087 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.551(lit.)
Flash point:
190 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
pka
9.47±0.10(Predicted)
form 
Liquid
Specific Gravity
1.087
color 
Colorless to yellow
Sensitive 
Air Sensitive
BRN 
106962
InChIKey
HVLUYXIJZLDNIS-UHFFFAOYSA-N
CAS DataBase Reference
30433-91-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36-37/39
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HazardClass 
8
PackingGroup 
II
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
423270
Product name
2-Thiopheneethylamine
Purity
96%
Packaging
1g
Price
$18
Updated
2024/03/01
Sigma-Aldrich
Product number
423270
Product name
2-Thiopheneethylamine
Purity
96%
Packaging
5g
Price
$148
Updated
2024/03/01
TCI Chemical
Product number
A1637
Product name
2-(2-Aminoethyl)thiophene
Purity
>98.0%(GC)
Packaging
25g
Price
$58
Updated
2024/03/01
TCI Chemical
Product number
A1637
Product name
2-(2-Aminoethyl)thiophene
Purity
>98.0%(GC)
Packaging
250g
Price
$365
Updated
2024/03/01
Alfa Aesar
Product number
A10920
Product name
2-Thiopheneethylamine, 98%
Packaging
1g
Price
$35.65
Updated
2024/03/01
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Thiophene-2-ethylamine Chemical Properties,Usage,Production

Chemical Properties

A colorless to yellow liquid with unstable properties requiring protection with nitrogen gas. It appears as a light yellow clear liquid, but turns red upon prolonged exposure.

Uses

[2-(Thiophene-2-yl)ethyl]amine is used in the synthesis of geldanamycin derivatives as HCV replication inhibitors targetting Hsp90.

Uses

2-Thiopheneethylamine (2-thiophene ethyl amine, 2-(thien-2-yl)ethylamine) is suitable to functionalize multiwall carbon nanotubes (MWCNT).
It may be used as a reactant in the synthesis of pyrimidine derivatives by reacting with various isothiocyanatoketones and acylguanidines derivatives by reacting with aroyl S-methylisothiourea.

General Description

2-Thiopheneethylamine (2-(thiophen-2-yl)ethanamine) is an aromatic amine. It undergoes microwave induced condensation with iminodiacetic acid to form the corresponding piperazine-2,6-dione derivatives. Its effect as a probable substitute to the pyridine ligand on the performance of poly(3-hexylthiophene)/CdSe hybrid solar cells has been investigated.

Synthesis

N,N-Dimethylformamide (DMF) reacts with thiophene to obtain 2-thiophenecarbaldehyde, then reacts with isopropyl chloroacetate to obtain 2-thiopheneacetaldehyde, and then reacts with hydroxylamine hydrochloride to obtain 2-thiopheneacetaldehyde oxime, and finally reduced to give 2-thiopheneethylamine.

References

[1] M. BARWIOLEK. Structural and spectral studies of silver(I) complexes with new Schiff bases derived from 2-thiopheneethylamine and their application in thin layer deposition by spin and dip coating techniques[J]. Polyhedron, 2017, 124: Pages 12-21. DOI:10.1016/j.poly.2016.12.011.
[2] BHUSHAN D. VARPE S B J. Schiff Base of Isatin with 2-Thiopheneethylamine and Its Mannich Bases: Synthesis, Docking, and In Vitro Anti-Inflammatory and Antitubercular Activity[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 2: 372-379. DOI:10.1134/S1068162022020030.
[3] JUN YAN LEK. Understanding the Effect of Surface Chemistry on Charge Generation and Transport in Poly (3-hexylthiophene)/CdSe Hybrid Solar Cells[J]. ACS Applied Materials & Interfaces, 2011, 3 2: 287-292. DOI:10.1021/am100938f.
[4] SANDEEP KUMAR. Efficient synthesis of piperazine-2,6-dione and 4-(1H-indole-2-carbonyl)piperazine-2,6-dione derivatives and their evaluation for anticancer activity[J]. Medicinal Chemistry Research, 2013, 22 10: 4600-4609. DOI:10.1007/s00044-012-0438-7.

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Thiophene-2-ethylamine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
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View Lastest Price from Thiophene-2-ethylamine manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
2-Thiopheneethylamine 30433-91-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2023-09-18
Henan Aochuang Chemical Co.,Ltd.
Product
Thiophene-2-ethylamine 30433-91-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13
Career Henan Chemical Co
Product
Thiophene-2-ethylamine 30433-91-1
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10MT
Release date
2018-12-21

30433-91-1, Thiophene-2-ethylamineRelated Search:


  • 20(2-thienyl)ethylamine
  • 2-(2'-Thienyl) ethyl amine/ Thiophene-2-ethylamine
  • 2-(2-Aminoethyl)thiophene~Thiophene-2-ethylamine
  • 2-Thiopheneethylamin
  • Thiophene-2-Ethylamine ,99%
  • 2-(2-Thienyl)ethanamine
  • 2-Thiopheneethanamine
  • Thiophene-2-ethanamine
  • Thiophene-2-ethylamine,98%
  • 2-Thiophen-2-ylethanamine
  • 2-(2-thienyl)ethanamine(SALTDATA: FREE)
  • 2-ThiophenethylaMine
  • 2-(Thien-2-yl)ethylamine
  • 2-(thiophen-2-yl)ethan-1-aMine
  • ThiopheneEthaMine
  • [2-(Thiophene-2-yl)ethyl]aMine
  • THIOPHENE ETHYLAMINE
  • THIOPHENE-2-ETHYLAMINE
  • THIOPHENE-2-ETHYLAMINE HCL SALT
  • RARECHEM AL BW 0099
  • 2-(2-AMINOETHYL)THIOPHENE
  • 2-(2'-THIENYL)ETHYL AMINE
  • 2-(2-THIENYL)ETHYLAMINE
  • 2-(2-THIENYL)-1-ETHANAMINE
  • 2-(2-THIENYL)-1-ETHANAMINE HYDROCHLORIDE
  • 2-AMINOETHYLTHIOPHENE
  • 2-THIOPHENEETHYLAMINE
  • B-2-THIENYLETHYLAMINE
  • .beta.-2-Thienylethylamine
  • Thiophen-2-ylacetyl chloride
  • 2-Thiopheneethamine
  • 2-(2-Aminoethyl)thiophene &gt
  • 2-Thien-2-yL
  • Thiophene-2-ethylamine ISO 9001:2015 REACH
  • 2-(Thiophen-2-yl)ethylamine
  • Rotigotine Impurity 17
  • 30433-91-1
  • 423-27-0
  • 30433-14-3
  • C6H9SN
  • AMINE
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiophenes
  • Building Blocks
  • C4 to C6
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiophenes
  • Amines
  • Heterocyclic Compounds
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