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5-Methoxy-pyridin-3-ylamine

Product Name
5-Methoxy-pyridin-3-ylamine
CAS No.
64436-92-6
Chemical Name
5-Methoxy-pyridin-3-ylamine
Synonyms
5-Me;5-Methoxy-pyridin-3-;5-Methoxy-3-pyridinamine;5-Methoxypyridin-3-amine;5-Methoxy-3-aminopyridine;3-Amino-5-methoxypyridine;3-Pyridinamine, 5-methoxy-;5-Methoxy-pyridin-3-ylamine;5-Methoxy-pyridin-3-amine ,98%;5-Fluoro-2,6-dimethyl-4-pyrimidinamine
CBNumber
CB4875561
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
64436-92-6.mol
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5-Methoxy-pyridin-3-ylamine Property

Melting point:
64-65 °C(Solv: benzene (71-43-2))
Boiling point:
166-168 °C(Press: 15 Torr)
Density 
1.139±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
5.80±0.10(Predicted)
Appearance
Brown to reddish brown Solid
InChI
InChI=1S/C6H8N2O/c1-9-6-2-5(7)3-8-4-6/h2-4H,7H2,1H3
InChIKey
CTQPCFFQBYXOAJ-UHFFFAOYSA-N
SMILES
C1=NC=C(OC)C=C1N
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Safety

Risk Statements 
41
Safety Statements 
26-39
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories
Product number
4H56-1-9H
Product name
5-Methoxypyridin-3-amine
Purity
95%
Packaging
250mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA45403
Product name
3-Amino-5-methoxypyridine
Packaging
1g
Price
$125.5
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-9H
Product name
5-Methoxypyridin-3-amine
Purity
95%
Packaging
1g
Price
$135
Updated
2021/12/16
Matrix Scientific
Product number
057365
Product name
5-Methoxypyridin-3-amine
Purity
95%
Packaging
1g
Price
$163
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA45403
Product name
3-Amino-5-methoxypyridine
Packaging
2g
Price
$193.8
Updated
2021/12/16
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5-Methoxy-pyridin-3-ylamine Chemical Properties,Usage,Production

Synthesis

50720-12-2

64436-92-6

General procedure for the synthesis of 3-bromo-5-methoxypyridine from 3-bromo-5-methoxypyridine: 3-bromo-5-methoxypyridine (500 mg, 2.66 mmol), ammonium hydroxide (15 mL), and cobalt sulfate pentahydrate (33 mg, 0.13 mmol) were placed in a hermetically sealed tube and heated in a microwave reactor for 20 hours at 140 °C. After completion of the reaction, the reaction mixture was cooled to room temperature and the crude product was subjected to liquid-liquid separation between ethyl acetate and water. The organic layer was washed sequentially with water (3 times) and saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 84 mg of solid product in 25% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.72 (d, J = 5.4 Hz, 2H), 6.51 (t, J = 2.4 Hz, 1H), 3.79 (s, 3H) ppm; HPLC-MS: m/z 125.0.

References

[1] Organic Process Research and Development, 2012, vol. 16, # 5, p. 788 - 797
[2] Advanced Synthesis and Catalysis, 2013, vol. 355, # 4, p. 627 - 631
[3] European Journal of Medicinal Chemistry, 2015, vol. 106, p. 50 - 59
[4] Patent: US2007/167497, 2007, A1. Location in patent: Page/Page column 26
[5] Patent: US2014/336182, 2014, A1. Location in patent: Paragraph 0315

5-Methoxy-pyridin-3-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methoxy-pyridin-3-ylamine Suppliers

China 153 Germany 1 India 1 United Kingdom 3 United States 18 Global 176
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from 5-Methoxy-pyridin-3-ylamine manufacturers

Career Henan Chemical Co
Product
3-Amino-5-methoxypyridine 64436-92-6
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-25

64436-92-6, 5-Methoxy-pyridin-3-ylamineRelated Search:

3-Amino-4-pyrazolecarbonitrile 2-Methylamino-3-amino-6-methoxypyridine 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID 5-METHOXY-PYRIDIN-2-YLAMINE 2-Chloro-3-methoxy-5-nitropyridine 5-Methoxy-pyridin-3-ylamine 3-Amino-2,6-dibromo-5-ethoxypyridine 3-Methoxy-5-nitropyridin-2-ol 3-Amino-6-methoxypyridine-2-carboxylic acid 3-AMINO-6-METHOXY-2-METHYLAMINO-PYRIDINE, DIHYDROCHLORIDE SPECIALITY CHEMICALS 6-METHOXY-PYRIDIN-2-YLAMINE 2-Amino-3-methoxypyridine 2-METHOXY-PYRIDIN-3-YLAMINE 2-METHOXY-5-AMINOPYRIDINE 6-METHOXY-PYRIDIN-3-YLAMINE,6-METHOXY-PYRIDIN-3-YLAMINE 5-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 2,3-Diamino-6-methoxypyridine 5-AMINO-2-METHOXY-ISONICOTINIC ACID 6-Bromo-2-methoxy-pyridin-3-ylamine ,97%,6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE

  • 5-Methoxy-pyridin-3-ylamine
  • 3-Amino-5-methoxypyridine
  • 5-Methoxy-3-pyridinamine
  • 5-Methoxy-3-aminopyridine
  • 5-Methoxypyridin-3-amine
  • 5-Methoxy-pyridin-3-amine ,98%
  • 5-Methoxy-pyridin-3-
  • 3-Pyridinamine, 5-methoxy-
  • 5-Fluoro-2,6-dimethyl-4-pyrimidinamine
  • 5-Me
  • 64436-92-6
  • 64436-93-2
  • Heterocyclic Compounds