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Methoxy-PEG-propionicacid-N-succinimidylester

Product Name
Methoxy-PEG-propionicacid-N-succinimidylester
CAS No.
174569-25-6
Chemical Name
Methoxy-PEG-propionicacid-N-succinimidylester
Synonyms
m-PEG17-NHS ester;Methyl-PEGn-NHS (n=12,13,24);m-PEGn-NHS ester;mPEG24-NHS;MPEGn-SPA 2K, 5K, 10K, 20K;Methoxy-PEG-NHS average M.W. 2000;alpha-[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-omega-methoxypoly(oxy-1,2-ethanediyl)
CBNumber
CB51074968
Molecular Formula
(C2H4O)nC8H11NO5
Formula Weight
0
MOL File
174569-25-6.mol
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Methoxy-PEG-propionicacid-N-succinimidylester Property

storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM, DMF
form 
solid
color 
white to off-white
α-end
methoxy
Ω-end
NHS ester
InChI
InChI=1S/C10H15NO6/c1-15-6-7-16-5-4-10(14)17-11-8(12)2-3-9(11)13/h2-7H2,1H3
InChIKey
IMSXKORGOVQCNT-UHFFFAOYSA-N
SMILES
O(N1C(CCC1=O)=O)C(=O)CCO{-}CC{+n}OC
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-21104
Product name
m-PEG12-NHSester
Purity
98%
Packaging
100mg
Price
$175
Updated
2021/12/16
BroadPharm
Product number
BP-22250
Product name
m-PEG25-NHSester
Purity
97%
Packaging
100mg
Price
$220
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG1880
Product name
MeO-dPEG(3)-NHS
Packaging
100mg
Price
$270
Updated
2021/12/16
BroadPharm
Product number
BP-24281
Product name
m-PEG17-NHSester
Purity
98%
Packaging
50mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-22248
Product name
m-PEG37-NHSester
Purity
97%
Packaging
100mg
Price
$320
Updated
2021/12/16
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Methoxy-PEG-propionicacid-N-succinimidylester Chemical Properties,Usage,Production

Description

m-PEG12-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reagent type: chemical modification reagent
reactivity: amine reactive

IC 50

PEGs

References

[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Methoxy-PEG-propionicacid-N-succinimidylester Preparation Products And Raw materials

Raw materials

Preparation Products

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Methoxy-PEG-propionicacid-N-succinimidylester Suppliers

China 35 Germany 1 United States 2 Global 38
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

174569-25-6, Methoxy-PEG-propionicacid-N-succinimidylesterRelated Search:

DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) METHYL ISOCYANOACETATE Benzyl isocyanide Ferric acetylacetonate TERT-BUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE N-BUTYLISOCYANIDE PHENYLSELENOL Tris(2,4-pentanedionato)chroMiuM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) SALCOMINE Ethyl isocyanoacetate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Cupric acetylacetonate Aluminum acetylacetonate Tosylmethyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE

  • MPEGn-SPA 2K, 5K, 10K, 20K
  • alpha-[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-omega-methoxypoly(oxy-1,2-ethanediyl)
  • Methyl-PEGn-NHS (n=12,13,24)
  • m-PEG17-NHS ester
  • m-PEGn-NHS ester
  • mPEG<sub>24</sub>-NHS
  • Methoxy-PEG-NHS average M.W. 2000
  • 174569-25-6
  • C2H4OnC8H11NO5
  • C38H71NO20
  • C54H103NO28
  • Polydispersed PEG