ChemicalBook > CAS DataBase List > 5-Pyrimidinecarboxylic acid

5-Pyrimidinecarboxylic acid

Product Name
5-Pyrimidinecarboxylic acid
CAS No.
4595-61-3
Chemical Name
5-Pyrimidinecarboxylic acid
Synonyms
AKOS 91242;Pyrimidine-5-carb;RARECHEM AK ML 0570;5-Carboxypyrimidine;5-Pyrimidinecarboxylicaci;PyriMidin-5-carboxylic acid;5-PYRIMIDINECARBOXYLIC ACID;PYRIMIDINE-5-CARBOXYLIC ACID;PYRIMIDINE-5-CARBOXILIC ACID;Pyrimidine-5-carboxylic a...
CBNumber
CB5108813
Molecular Formula
C5H4N2O2
Formula Weight
124.1
MOL File
4595-61-3.mol
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5-Pyrimidinecarboxylic acid Property

Melting point:
259 °C
Boiling point:
318.7±15.0 °C(Predicted)
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.74±0.10(Predicted)
form 
Solid
color 
White to Yellow to Orange
λmax
275nm(H2O)(lit.)
InChIKey
IIVUJUOJERNGQX-UHFFFAOYSA-N
CAS DataBase Reference
4595-61-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36
Safety Statements 
22-26-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003995
Product name
pyrimidine-5-carboxylic acid
Purity
Aldrich
Packaging
250mg
Price
$87.5
Updated
2025/07/31
TCI Chemical
Product number
P1909
Product name
Pyrimidine-5-carboxylic Acid
Purity
>97.0%(GC)(T)
Packaging
1g
Price
$314
Updated
2025/07/31
TRC
Product number
P997373
Product name
pyrimidine-5-carboxylic acid
Packaging
100mg
Price
$75
Updated
2021/12/16
Usbiological
Product number
296388
Product name
Pyrimidine-5-carboxylic acid
Packaging
1g
Price
$355
Updated
2021/12/16
Chem-Impex
Product number
43675
Product name
Pyrimidine-5-carboxylicacid,≥97%(GC)
Purity
≥97%(GC)
Packaging
1G
Price
$431.02
Updated
2021/12/16
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5-Pyrimidinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White to off-white solid

Uses

Pyrimidine-5-carboxylic Acid is used in the preparation of heterocyclic compounds as an antiviral agent.

Synthesis

40929-50-8

4595-61-3

General procedure for the synthesis of pyrimidine-5-carboxylic acid from ethyl pyrimidine-5-carboxylate: 19.50 mL (149 mmol) of ethyl pyrimidine-5-carboxylate was mixed with 40 mL of 4 M sodium hydroxide solution at room temperature, and the reaction was oscillated for 0.1 hour. Subsequently, 40 mL of 4 M hydrochloric acid solution was added for neutralization. The precipitate formed in the reaction was separated by filtration, washed with petroleum ether and then dried. Finally, 14.80 g of pyrimidine-5-carboxylic acid was obtained in a yield of 80% of the theoretical value.

References

[1] Patent: US2007/259855, 2007, A1. Location in patent: Page/Page column 17-18

5-Pyrimidinecarboxylic acid Preparation Products And Raw materials

Raw materials

Nitrogen Carbon dioxide Ethyl chloroformate Tetrahydrofuran 5-Bromopyrimidine Sulfuric acid n-Butyllithium Sodium carbonate

Preparation Products

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View Lastest Price from 5-Pyrimidinecarboxylic acid manufacturers

Dideu Industries Group Limited
Product
5-Pyrimidinecarboxylic acid 4595-61-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Pyrimidinecarboxylic acid 4595-61-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Pyrimidinecarboxylic acid 4595-61-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

4595-61-3, 5-Pyrimidinecarboxylic acidRelated Search:

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