Methyl 3-amino-2-thiophenecarboxylate

Product Name: Methyl 3-amino-2-thiophenecarboxylate
CAS No.: 22288-78-4
Chemical Name: Methyl 3-amino-2-thiophenecarboxylate
Synonyms: METHYL 3-AMINOTHIOPHENE-2-CARBOXYLATE;M3AT2C;AKOS 92421;ina-5545-2;Methyl3-am;AKOS B020093;Methyl 3-amino-2-;3-Amino-2-thenoate;RARECHEM AM UC 0123;Methyl 3-amino-2-thi
CBNumber: CB5123399
Molecular Formula: C6H7NO2S
Formula Weight: 157.19
MOL File: 22288-78-4.mol

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Methyl 3-amino-2-thiophenecarboxylate Property

Melting point:: 62-64 °C (lit.)
Boiling point:: 100-102 °C/0.1 mmHg (lit.)
Density: 1.274 (estimate)
refractive index: 1.5500 (estimate)
Flash point:: 100-102°C/0.1mm
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Fine Crystalline Powder
pka: 1.86±0.10(Predicted)
color: Beige to beige-brown
Water Solubility: Slightly soluble in water.
BRN: 1365614
InChI: InChI=1S/C6H7NO2S/c1-9-6(8)5-4(7)2-3-10-5/h2-3H,7H2,1H3
InChIKey: TWEQNZZOOFKOER-UHFFFAOYSA-N
SMILES: C1(C(OC)=O)SC=CC=1N
CAS DataBase Reference: 22288-78-4(CAS DataBase Reference)
EPA Substance Registry System: 2-Thiophenecarboxylic acid, 3-amino-, methyl ester (22288-78-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36/37/39-22
WGK Germany: 3
RTECS: XM8347500
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 232904
Product name: Methyl 3-amino-2-thiophenecarboxylate
Purity: 99%
Packaging: 10g
Price: $43.15
Updated: 2025/07/31

Sigma-Aldrich

Product number: 232904
Product name: Methyl 3-amino-2-thiophenecarboxylate
Purity: 99%
Packaging: 50g
Price: $208.05
Updated: 2025/07/31

TCI Chemical

Product number: A1039
Product name: Methyl 3-Amino-2-thiophenecarboxylate
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $51
Updated: 2025/07/31

TCI Chemical

Product number: A1039
Product name: Methyl 3-Amino-2-thiophenecarboxylate
Purity: >98.0%(GC)(T)
Packaging: 100g
Price: $157
Updated: 2025/07/31

TRC

Product number: A612075
Product name: 3-Amino-2-methoxycarbonylthiophene
Packaging: 100g
Price: $360
Updated: 2021/12/16

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Methyl 3-amino-2-thiophenecarboxylate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Methyl 3-amino-2-thiophenecarboxylate was used in:

the synthesis of 4-nitro and 4-aminothienyl ureas
total synthesis of quinazolinocarboline alkaloids
preparation of thienopyrimidinone analogs

Uses

Methyl 3-amino-2-thiophenecarboxylate is the starting material for synthesising Belvarafenib. Belvarafenib is a small-molecule RAF dimer (type II) inhibitor with potential antitumour activity.

General Description

Methyl 3-amino-2-thiophenecarboxylate reacts with hydrazonoyl chlorides in the presence of triethylamine to yield corresponding N-arylamidrazones.

Methyl 3-amino-2-thiophenecarboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate 1.3-Dichloropropene Sodium methoxide solution Acrylonitrile

Preparation Products

2,4-DICHLOROTHIENO[3,2-D]PYRIMIDINE 3-(Acetylamino)thiophene-2-carboxylic acid 3-(1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLIC ACID 2,4-Dichlorothieno[3,2-d]pyrimidine Methyl 3-aminosulfonylthiophene-2-carboxylate METHYL 3-CHLOROTHIOPHENE-2-CARBOXYLATE 3-CHLOROTHIOPHENE-2-CARBOXAMIDE METHYL 3-[(2-BROMOACETYL)AMINO]THIOPHENE-2-CARBOXYLATE 2,4-DIHYDROXYTHIENO[3,2-D]PYRIMIDINE

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Methyl 3-amino-2-thiophenecarboxylate Suppliers

Americas 1 Austria 1 Belgium 4 Canada 1 China 347 Europe 3 France 2 Germany 10 India 22 Japan 3 Russia 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 21 United States 58 Global 478

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View Lastest Price from Methyl 3-amino-2-thiophenecarboxylate manufacturers

Shandong Vital Biotechnology Co., Ltd.

Product: Methyl3-amino-2-thiophenecarboxylate 22288-78-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100tons
Release date: 2025-11-20

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Methyl 3-amino-2-thiophenecarboxylate 22288-78-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-25

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Methyl 3-amino-2-thiophene carboxylate 22288-78-4
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-26

22288-78-4, Methyl 3-amino-2-thiophenecarboxylate Related Search:

METSULFURON METHYL 2-Thiophenecarboxylic acid Methylparaben Kresoxim-methyl Methyl anthranilate Methyl benzoate Methyl acrylate Bensulfuron methyl Methyl 2-iodobenzoate Methyl formate Trimethoxymethane Methyl acetate RESMETHRIN 3-AMINOTHIOPHENE methyl 3-bromo-6-methylpicolinate Methyl 3-amino-2-pyrazinecarboxylate Thiophanate-methyl Methyl

AMino-2-thiophenecarboxylate

AMino thiophene - 2-3 - carboxylic acid Methyl ester

Methyl3-aMino-2-thiophenecarbo

RARECHEM AM UC 0123

3-amino-2-thiophenecarboxylicacimethylester

ina-5545-2

Methyl3-amino-2-thenoate

3-AMINO-2-METHOXYCARBONYLTHIOPHENE

3-AMINO-2-THIOPHENECARBOXYLIC ACID METHYL ESTER

3-AMINOTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

AKOS 92421

AKOS B020093

ASINEX-REAG BAS 05504796

LABOTEST-BB LT00112337

M3AT2C

METHYL 3-AMINO-2-THIOPHENECARBOXYLATE

METHYL-3-AMINO-2-THIOPHENE FORMATE

METHYL 3-AMINOTHIOPHENE-2-CARBOXYLATE

METHYL 3-AMINO-2-THIOPHENECARBOXYLATE, 9 9%

Methyl 3-aminothiophene-2-carboxylate, 98+%

3-AMINO-2-THIOPHENE METHYLFORMATE

Name: 3-Aminothiophene-2-carboxylic acid methyl ester

Methyl-3-Aminothiophene-2-Carb

3-amino-2-thiophenecarboxylate

3-aminothiophene-2-carboxyL

Methyl 3-amino-2-

3-Aminothiophen-2-carboxylic acid methyl ester

Methyl 3-amino-2-thiophenecarboxylate ,98%

Methyl3-am

Methy1-3-amino-2-thiophene carboxylate

3-Amino-2-thenoate

3-aminothiophene-2-carboxylate

Methyl 3-aminothiophene-2-carboxylate ,95%

Methyl 3-amino-2-thi

Methyl 3-aMino-2-thiophenecarboxylate, 99% 10GR

Methyl 3-aMino-2-thiophenecarboxylate, 99% 50GR

2-Methoxycarbonyl-3-aMino-thiophene

3-aMino-2-carboMethoxythiophene

Methyl 3-Amino-2-thiophenecarboxylate &gt

3-amino-2-carboxylate methyl thiophene

Methyl 3-amino-2-thiophenoate

Methyl 3-amino-2-thiophenecarboxylate USP/EP/BP

Methyl 3-aminothiophene-2-carboxylateQ: What is Methyl 3-aminothiophene-2-carboxylate Q: What is the CAS Number of Methyl 3-aminothiophene-2-carboxylate Q: What is the storage condition of Methyl 3-aminothiophene-2-carboxylate Q: What are the applications of Methyl 3-aminothiophene-2-carboxylate

Methyl-3-amino2-thiopene carboxylate

Methyl-3-aminothiophen-3-carboxylate

22288-78-4

22288-74-4

C6H7NO2S

Heterocyclic Building Blocks

Thiophenes

Building Blocks

API intermediates

Thiophenes & Benzothiophenes

Pharmaceutical intermediate

Sulphur Derivatives

INTERMEDIATESOFTENOXICAM

Esters

Thiophenes & Benzothiophenes