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6-hydroxydexamethasone

Product Name
6-hydroxydexamethasone
CAS No.
55879-47-5
Chemical Name
6-hydroxydexamethasone
Synonyms
6-hydroxydexamethasone;6β-hydroxy Dexamethasone;Dexamethasone Impurity 12;Dexamethasone 6β-Hydroxy Impurity;Dexamethasone 6beta-Hydroxy Impurity;6-Hydroxydexamethasone Solution, 100ppm;(6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CBNumber
CB51341435
Molecular Formula
C22H29FO6
Formula Weight
408.46
MOL File
55879-47-5.mol
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6-hydroxydexamethasone Property

Melting point:
259-262°C
Boiling point:
613.2±55.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Dioxane (Very Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
12.06±0.70(Predicted)
color 
White to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22099
Product name
6β-hydroxy Dexamethasone
Purity
≥98%
Packaging
500μg
Price
$214
Updated
2023/06/20
Cayman Chemical
Product number
22099
Product name
6β-hydroxy Dexamethasone
Purity
≥98%
Packaging
1mg
Price
$405
Updated
2023/06/20
TRC
Product number
H939500
Product name
6β-HydroxyDexamethasone
Packaging
2.5mg
Price
$215
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0002203
Product name
6-BETA-HYDROXY DEXAMETHASONE
Purity
95.00%
Packaging
5MG
Price
$496.21
Updated
2021/12/16
AK Scientific
Product number
3637CA
Product name
6beta-Hydroxydexamethasone
Packaging
1mg
Price
$559
Updated
2021/12/16
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6-hydroxydexamethasone Chemical Properties,Usage,Production

Description

6β-hydroxy Dexamethasone is a metabolite of dexamethasone (Item Nos. 11015 | 20340) that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans. The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.

Chemical Properties

Off-White Solid

Uses

The hydrophilic metabolite of Dexamethasone (D298800).

6-hydroxydexamethasone Preparation Products And Raw materials

Raw materials

Preparation Products

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6-hydroxydexamethasone Suppliers

BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14336
Advantage
58

55879-47-5, 6-hydroxydexamethasoneRelated Search:


  • 6-hydroxydexamethasone
  • Dexamethasone 6β-Hydroxy Impurity
  • Dexamethasone Impurity 12
  • 6-Hydroxydexamethasone Solution, 100ppm
  • (6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • Dexamethasone 6beta-Hydroxy Impurity
  • 6β-hydroxy Dexamethasone
  • 55879-47-5
  • C22H29FO6
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids