ChemicalBook > CAS DataBase List > berberrubine

berberrubine

Product Name: berberrubine
CAS No.: 15401-69-1
Chemical Name: berberrubine
Synonyms: Berberrubine chloride;Chileninone;Beroline;grubbiness;Nerberrubine;berberrubine;Beroline chloride;9-Berberoline chloride;Berberubine chloride form;Berberrubine/Berberrubine chloride
CBNumber: CB51356211
Molecular Formula: C19H16ClNO4
Formula Weight: 357.78764
MOL File: 15401-69-1.mol

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berberrubine Property

Melting point:: 245℃ (DEC.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Off-White to Dark Yellow
Stability:: Hygroscopic
InChI: InChI=1S/C19H15NO4.ClH/c1-22-16-3-2-11-6-15-13-8-18-17(23-10-24-18)7-12(13)4-5-20(15)9-14(11)19(16)21;/h2-3,6-9H,4-5,10H2,1H3;1H
InChIKey: GYFSYEVKFOOLFZ-UHFFFAOYSA-N
SMILES: [Cl-].O1C([H])([H])OC2=C1C([H])=C1C(=C2[H])C2C([H])=C3C([H])=C([H])C(=C(C3=C([H])[N+]=2C([H])([H])C1([H])[H])O[H])OC([H])([H])[H]

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B200095
Product name: BerberrubineChloride
Packaging: 1mg
Price: $50
Updated: 2021/12/16

TRC

Product number: B200095
Product name: BerberrubineChloride
Packaging: 5mg
Price: $150
Updated: 2021/12/16

TRC

Product number: B200095
Product name: BerberrubineChloride
Packaging: 2.5mg
Price: $100
Updated: 2021/12/16

Usbiological

Product number: 300000
Product name: Berberrubine
Packaging: 10mg
Price: $390
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb593783
Product name: Berberrubine
Packaging: 20mg
Price: $391
Updated: 2021/12/16

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berberrubine Chemical Properties,Usage,Production

Chemical Properties

Soluble in acidic solution, insoluble in petroleum ether, chloroform and other solvents. Derived from the roots of Thalictrum polygamun Muhl.

Uses

Berberrubine Chloride is a novel alkaloid with novel nitric-oxide donating activity. Antitumor and an antimicrobial agent.

Definition

ChEBI: Berberrubine is an alkaloid.

in vivo

Berberrubine (oral administration; 10-20 mg/kg; 7 days) has a beneficial effect in a mouse colitis model^[3].

Animal Model:	DSS (HY-116282) treated male Balb/c mice aged 6 weeks old^[3]
Dosage:	10 and 20 mg/kg
Administration:	Oral administration (p.o.); 7 days
Result:	Significantly reduced the disease activity index (DAI) with prolonged colon length and increased bodyweight at dose of 20 mg/kg. Significantly ameliorated the DSS-induced colonic pathological alternations and decreased histological scores. Markedly attenuated colonic inflammation by alleviating inflammatory cell infiltration and inhibiting myeloperoxidase (MPO) and cytokines (TNF-α, IFN-γ, IL-1β, IL-6, IL-4 and IL-10) productions in DSS mice. Substantially upregulated the expression of tight junction proteins (zonula occludens-1, zonula occludens-2, claudin-1, occludin) and mRNA expression of mucins (mucin-1 and mucin-2), and decreased the Bax/Bcl-2 ratio.

berberrubine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from berberrubine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: berberrubine 15401-69-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Shanghai Standard Technology Co., Ltd.

Product: Berberrubine 15401-69-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥90%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-27

Baoji Guokang Healthchem co.,ltd

Product: berberrubine 15401-69-1
Price: US $95.00/mg
Min. Order: 20mg
Purity: 99%
Supply Ability: 10kg
Release date: 2021-06-08

15401-69-1, berberrubineRelated Search:

Citric acid Schisandrin A Tetrahydroberberine Hydroxysafflor yellow A BERBAMINE DIHYDROCHLORIDE BERBAMINE BERBERINE ACID SULFATE Salicylic acid Resveratrol (+)-Camptothecin Rutin Coptisine chloride Glycyrrhizic acid epiberberine Potassium iodide Berberine hydrochloride BERBERINE CHLORIDE Berberine

5,6-Dihydro-9-hydroxy-10-methoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride

9-Berberoline chloride

9-Demethoxy-9-hydroxyberberinium chloride

Berberrubine chloride

Beroline chloride

berberrubine

Chileninone

Nerberrubine

9-Hydroxy-10-methoxy-5,6-dihydro-[1,3]dioxolo-[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chlo

Berberubine chloride form

Beroline

BERBERRUBINE,HYDROCHLORIDE,DIHYDRATE

9-hydroxy-10-methoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

grubbiness

10-methoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium-9-olate

Berberrubine/Berberrubine chloride

Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9-hydroxy-10-methoxy-, chloride (1:1)

9-Berberoline Chloride|||Beroline|||Beroline Chloride|||Berberrubine|||9-Berberoline

Berberrubine chloride, 10 mM in DMSO

15401-69-1

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract