ChemicalBook > CAS DataBase List > 4'-Fluoro-2'-hydroxyacetophenone

4'-Fluoro-2'-hydroxyacetophenone

Product Name
4'-Fluoro-2'-hydroxyacetophenone
CAS No.
1481-27-2
Chemical Name
4'-Fluoro-2'-hydroxyacetophenone
Synonyms
1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one;1-(4-fluoro-2-hydroxyphenyl)ethanone;4-FLUORO-2-HYDROXYACETOPHENONE;4'-Fluoro-2'-hydroxy;4-FLUORO-2-HYDROXYACETOPHE;uoro-2'-hydroxyacetophenone;4-Fluoro-2-hydroxyacethophenone;4'-Fluoro-2'-hydroxyacetophenone;4'-Fluoro-2'-hydroxyacetophenone>4'-Fluoro-2'-hydroxyacetophenone98%
CBNumber
CB5147045
Molecular Formula
C8H7FO2
Formula Weight
154.14
MOL File
1481-27-2.mol
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4'-Fluoro-2'-hydroxyacetophenone Property

Melting point:
32-34°C
Boiling point:
65°C 2mm
Density 
1.1850 (estimate)
Flash point:
98°C
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to lump
pka
9.17±0.10(Predicted)
color 
White to Almost white
BRN 
2249799
InChI
InChI=1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3
InChIKey
HLTBTUXAMVOKIH-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(F)C=C1O)C
CAS DataBase Reference
1481-27-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29147000
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
466964
Product name
4′-Fluoro-2′-hydroxyacetophenone
Purity
98%
Packaging
5g
Price
$52.82
Updated
2025/07/31
TCI Chemical
Product number
F0723
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
>97.0%(GC)
Packaging
5g
Price
$61
Updated
2025/07/31
TCI Chemical
Product number
F0723
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
>97.0%(GC)
Packaging
25g
Price
$243
Updated
2025/07/31
TRC
Product number
F597380
Product name
4''-Fluoro-2''-hydroxyacetophenone
Packaging
5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J93085
Product name
4'-Fluoro-2'-hydroxyacetophenone
Packaging
5g
Price
$25
Updated
2021/12/16
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4'-Fluoro-2'-hydroxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

Colorless to yellow liquid

Uses

4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.

Preparation

Preparation by Fries rearrangement of 3-fluorophenyl acetate with aluminium chloride without solvent at 160–180° (75%) (88–90%).

General Description

4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n.

4'-Fluoro-2'-hydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Fluoro-2'-hydroxyacetophenone Suppliers

Americas 1 Austria 1 China 207 Europe 3 France 1 Germany 4 India 13 Italy 1 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 16 United States 29 Global 279
Taizhou Wealsun Biotech Co., Ltd
Tel
18351140886; 18351140886
Email
wealsunbio@126.com
Country
China
ProdList
108
Advantage
58
Suzhou Lyran Biopharma And Technology CO.,LTD.
Tel
18949975665; 18949975665
Email
1184800090@qq.com
Country
China
ProdList
347
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 4'-Fluoro-2'-hydroxyacetophenone manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4'-Fluoro-2'-hydroxyacetophenone 1481-27-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Career Henan Chemical Co
Product
4'-Fluoro-2'-hydroxyacetophenone 1481-27-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-30

1481-27-2, 4'-Fluoro-2'-hydroxyacetophenoneRelated Search:

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  • 4-FLUORO-2-HYDROXYACETOPHENONE
  • 4-Fluoro-2-hydroxyacethophenone, 98%
  • 4'-Fluoro-2'-hydroxyacetophenone 98%
  • 4'-Fluoro-2'-hydroxyacetophenone98%
  • 4'-fluoro-2'-hydroxyacetophenone,1-(4-fluoro-2-hydroxyphenyl)ethanone
  • 4-FLUORO-2-HYDROXYACETOPHE
  • uoro-2'-hydroxyacetophenone
  • 1-(4-fluoro-2-hydroxyphenyl)ethanone
  • 4'-Fluoro-2'-hydroxy
  • 1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one
  • 4'-Fluoro-2'-hydroxyacetophenone&gt
  • Ethanone, 1-(4-fluoro-2-hydroxyphenyl)-
  • 4'-Fluoro-2'-hydroxyacetophenone
  • 4-Fluoro-2-hydroxyacethophenone
  • 1481-27-2
  • 1181-27-2
  • FC6H3OHCOCH3
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • Carbonyl Compounds
  • C7 to C8
  • Aromatic Acetophenones & Derivatives (substituted)
  • ketone
  • Adehydes, Acetals & Ketones
  • Fluorine Compounds
  • Phenols
  • C7 to C8
  • Carbonyl Compounds
  • Ketones