ChemicalBook > CAS DataBase List > 4-BROMO-3-HYDROXYPYRIDINE

4-BROMO-3-HYDROXYPYRIDINE

Product Name
4-BROMO-3-HYDROXYPYRIDINE
CAS No.
161417-28-3
Chemical Name
4-BROMO-3-HYDROXYPYRIDINE
Synonyms
4-Bromopyridin-3-ol;4-BROMO-3-PYRIDINOL;3-Pyridinol, 4-bromo-;4-boro-3-hydroxypyridine;4-BROMO-3-HYDROXYPYRIDINE;4-BROMO-3-HYDROXYOPYRIDINE;4-BROMO-3-HYDROXYPYRIDINE ISO 9001：2015 REACH
CBNumber
CB5147797
Molecular Formula
C5H4BrNO
Formula Weight
174
MOL File
161417-28-3.mol
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4-BROMO-3-HYDROXYPYRIDINE Property

Melting point:
134-136°C
Boiling point:
316.2±22.0 °C(Predicted)
Density 
1.788±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Sparingly), Ethyl Acetate
form 
Solid
pka
6.57±0.10(Predicted)
color 
White to Off-White
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC
Product number
B684473
Product name
4-Bromo-3-hydroxypyridine
Packaging
250mg
Price
$65
Updated
2021/12/16
TRC
Product number
B684473
Product name
4-Bromo-3-hydroxypyridine
Packaging
5g
Price
$525
Updated
2021/12/16
Apolloscientific
Product number
OR301092
Product name
4-Bromo-3-hydroxypyridine
Purity
96%
Packaging
10g
Price
$551
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-9-04
Product name
4-Bromo-3-hydroxypyridine
Purity
96%
Packaging
10g
Price
$608
Updated
2021/12/16
ChemScene
Product number
CS-W006061
Product name
4-Bromo-3-hydroxypyridine
Purity
99.98%
Packaging
25g
Price
$705
Updated
2021/12/16
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4-BROMO-3-HYDROXYPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Synthesis

98976-81-9

161417-28-3

The general procedure for the synthesis of 4-bromo-3-hydroxypyridine from the compound (CAS: 98976-81-9) is as follows: to a solution of 4-bromo-3-pyridinyl diethylcarbamate (1.24 g, 4.50 mmol) in methanol (10 mL) was added methanolic solution of sodium methanolate (2.04 g, 9.40 mmol) at 20°C and the resulting mixture was refluxed for 1.5 hours. Upon completion of the reaction, methanol was removed by distillation under reduced pressure, ethyl acetate (15 mL) and water (1 mL) were added, and then the pH was adjusted to 9 with 20% aqueous sulfuric acid. the organic layer was separated, and the residue was washed with ethyl acetate (3 x 5 mL). The organic layers were combined, dried and concentrated with anhydrous sodium sulfate. The crude product was purified by rapid chromatography on silica gel, eluting sequentially with hexane/ethyl acetate (1:1 and 1:2) to give 691 mg (89% yield) of 4-bromo-3-hydroxypyridine.TLC Rf value was 0.38 (1:2 hexane/ethyl acetate). Mass spectra (DCI/NH3) m/e 174 (with 79 Br) and 176 (M+H)+ (with 81 Br).1H NMR (CDCl3, 300 MHz) δ: 8.43 (d, J=1.5 Hz, 1H, ArH), 8.02 (d, J=7.2 Hz, 1H, ArH), 7.54 (dd, J=7.2,1.5 Hz. 1H, ArH).

References

[1] Patent: US5914328, 1999, A
[2] Patent: US5948793, 1999, A

4-BROMO-3-HYDROXYPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-3-HYDROXYPYRIDINE Suppliers

Canada 1 China 124 Europe 1 Germany 2 India 2 United Kingdom 5 United States 15 Global 150
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 4-BROMO-3-HYDROXYPYRIDINE manufacturers

Dideu Industries Group Limited
Product
4-BROMO-3-HYDROXYPYRIDINE 161417-28-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-24
Career Henan Chemical Co
Product
4-BROMO-3-HYDROXYPYRIDINE 161417-28-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2020-01-13

161417-28-3, 4-BROMO-3-HYDROXYPYRIDINERelated Search:

2,4,6-TRIBROMO-3-PYRIDINOL 4-BROMO-2-HYDROXYPYRIDINE 97%,4-BROMO-2-HYDROXYPYRIDINE 4-BROMO-3-METHOXYPYRIDINE 3-Bromo-2-methoxy-5-trifluoromethylpyridine 4-BROMO-3-HYDROXYPYRIDINE 2-BROMO-3-HYDROXYPYRIDINE (2-BROMO-3-PYRIDINOL),2-Bromo-3-pyridinol(2-Bromo-3-hydroxypyridine),2-BROMO-3-HYDROXYPYRIDINE 97%,2-BROMO-3-HYDROXYPYRIDINE 4-Amino-3-bromo-2-hydroxypyridine 2-amino-5-bromopyridin-3-ol 5-Bromo-2-hydroxypyridine-4-carboxylic acid METHYL 5-BROMO-2-HYDROXYPYRIDINE-3-CARBOXYLATE 3,5-DIBROMO-2-HYDROXYPYRIDINE 2-Bromo-4-Hydroxypyridine 2-BROMO-6-HYDROXYPYRIDINE 2-BROMO-5-HYDROXYPYRIDINE,6-BROMO-3-HYDROXYPYRIDINE,2-BROMO-5-HYDROXYPYRIDINE ,98% 5-BROMO-2-HYDROXYPYRIDINE, 97%%,3-Bromo-6-hydroxypyridine,5-BROMO-2-HYDROXYPYRIDINE 5-BROMO-2-HYDROXYPYRIDINE-3-CARBOXYLIC ACID 3-AMINO-5-BROMO-2-HYDROXYPYRIDINE 3-BROMO-5-HYDROXYPYRIDINE 98.5+%,5-Bromo-3-hydroxypyridine 5-Bromo-3-pyridinol,3-BROMO-5-HYDROXYPYRIDINE,5-BROMO-3-HYDROXYPYRIDINE

  • 4-BROMO-3-HYDROXYPYRIDINE
  • 4-BROMO-3-PYRIDINOL
  • 4-BROMO-3-HYDROXYOPYRIDINE
  • 3-Pyridinol, 4-bromo-
  • 4-Bromopyridin-3-ol
  • 4-boro-3-hydroxypyridine
  • 4-BROMO-3-HYDROXYPYRIDINE ISO 9001：2015 REACH
  • 161417-28-3
  • Pyridines
  • Pyridines, Pyrimidines, Purines and Pteredines
  • pharmacetical
  • Pyridine
  • Chemical Amines
  • Amines
  • Aromatics
  • Heterocycles