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Methyl 5-Methyl-2-Nitrobenzoate

Product Name
Methyl 5-Methyl-2-Nitrobenzoate
CAS No.
20587-30-8
Chemical Name
Methyl 5-Methyl-2-Nitrobenzoate
Synonyms
Methyl 6-nitro-m-toluate;5-Methyl-2-Nitrobenzoate Methyl;Methyl 5-Methyl-2-Nitrobenzoate;6-Nitro-m-toluic Acid Methyl Ester;Methyl 5-Methyl-2-nitrobenzoate >5-Methyl-2-nitrobenzoic acid methyl ester;Benzoic acid, 5-methyl-2-nitro-, methyl ester;5-methyl-2-nitrobenzoic acid methyl ester 90%;2-(Ethoxycarbonyl)-4-methylnitrobenzene, 3-(Ethoxycarbonyl)-4-nitrotoluene;2-(Methoxycarbonyl)-4-methylnitrobenzene, 3-(Methoxycarbonyl)-4-nitrotoluene
CBNumber
CB51564263
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
20587-30-8.mol
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Methyl 5-Methyl-2-Nitrobenzoate Property

Melting point:
77-79℃
Boiling point:
305.1±22.0 °C(Predicted)
Density 
1.255
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
color 
White to Almost white
InChIKey
KFOICDVZQKFCGM-UHFFFAOYSA-N
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S914665
Product name
METHYL 5-METHYL-2-NITROBENZOATE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
S914665
Product name
METHYL 5-METHYL-2-NITROBENZOATE
Purity
Aldrich
Packaging
250mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
M2544
Product name
Methyl 5-Methyl-2-nitrobenzoate
Purity
>98.0%(GC)
Packaging
5g
Price
$36
Updated
2025/07/31
TCI Chemical
Product number
M2544
Product name
Methyl 5-Methyl-2-nitrobenzoate
Purity
>98.0%(GC)
Packaging
25g
Price
$119
Updated
2025/07/31
TRC
Product number
B451623
Product name
METHYL 5-METHYL-2-NITROBENZOATE
Packaging
500mg
Price
$75
Updated
2021/12/16
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Methyl 5-Methyl-2-Nitrobenzoate Chemical Properties,Usage,Production

Synthesis

67-56-1

3113-72-2

20587-30-8

5-Methyl-2-nitrobenzoic acid (8 g, 44.198 mmol) was dissolved in methanol (80 mL) and the solution was cooled to 0°C. Sulfuric acid (5 mL) was added slowly and dropwise with stirring. Subsequently, the reaction mixture was heated to 90 °C and stirred continuously at this temperature for 16 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent 50% ethyl acetate/hexane). After completion of the reaction, excess methanol was removed by distillation under reduced pressure. The residue was poured into water (150 mL) and extracted with ethyl acetate (150 mL x 2). The organic phases were combined and washed sequentially with saturated sodium bicarbonate solution (50 mL x 2) and brine (20 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 5-methyl-2-nitrobenzoate (yield: 8 g, 93%). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.86-7.84 (d, 1H, J = 8Hz), 7.48 (s, 1H), 7.40-7.38 (d, 1H, J = 8Hz), 3.91 (s, 3H), 3.47 (s, 3H).

References

[1] Journal of Heterocyclic Chemistry, 1984, vol. 21, p. 1807 - 1816
[2] Patent: WO2015/38417, 2015, A1. Location in patent: Paragraph 151
[3] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 12, p. 4309 - 4315
[4] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 7, p. 2209 - 2224
[5] Chemische Berichte, 1909, vol. 42, p. 433

Methyl 5-Methyl-2-Nitrobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 5-Methyl-2-Nitrobenzoate Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from Methyl 5-Methyl-2-Nitrobenzoate manufacturers

Qingdao RENAS Polymer Material Co., Ltd.
Product
methyl 5-methyl-2-nitrobenzoate 20587-30-8
Price
US $0.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
10 tons
Release date
2025-05-12
Career Henan Chemical Co
Product
Methyl 5-Methyl-2-Nitrobenzoate 20587-30-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-03

20587-30-8, Methyl 5-Methyl-2-NitrobenzoateRelated Search:


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  • 5-methyl-2-nitrobenzoic acid methyl ester 90%
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  • Benzoic acid, 5-methyl-2-nitro-, methyl ester
  • 6-Nitro-m-toluic Acid Methyl Ester
  • 20587-30-8