ChemicalBook > CAS DataBase List > 3-Aminopyridine

3-Aminopyridine

Product Name
3-Aminopyridine
CAS No.
462-08-8
Chemical Name
3-Aminopyridine
Synonyms
pyridin-3-amine;462-08-0;462-08-0;3APY;3-pyridinamine;NSC 15040;AKOS 90977;3-aminepyridin;3-PYRIDYLAMINE;B-PYRIDYLAMINE
CBNumber
CB5178708
Molecular Formula
C5H6N2
Formula Weight
94.11
MOL File
462-08-8.mol
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3-Aminopyridine Property

Melting point:
60-63 °C(lit.)
Boiling point:
248 °C(lit.)
Density 
1.0308 (estimate)
refractive index 
1.5560 (estimate)
Flash point:
124 °C
storage temp. 
Poison room
solubility 
>1000g/l
form 
Liquid
pka
6.04(at 25℃)
color 
Clear colorless to yellow
PH
10 (100g/l, H2O, 20℃)
Water Solubility 
It is soluble in water as well as soluble in alcohol, benzene.
Sensitive 
Air Sensitive & Hygroscopic
Merck 
14,473
BRN 
105692
InChIKey
CUYKNJBYIJFRCU-UHFFFAOYSA-N
LogP
0.110
CAS DataBase Reference
462-08-8(CAS DataBase Reference)
NIST Chemistry Reference
3-Pyridinamine(462-08-8)
EPA Substance Registry System
3-Aminopyridine (462-08-8)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
23/24/25-33-36/37/38-25
Safety Statements 
36/37/39-45-37/39-28B-26
RIDADR 
UN 2671 6.1/PG 2
WGK Germany 
3
RTECS 
US1650000
F 
3-8-9-23
Hazard Note 
Toxic/Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333999
Toxicity
LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A78209
Product name
3-Aminopyridine
Purity
99%
Packaging
25g
Price
$47.6
Updated
2024/03/01
Sigma-Aldrich
Product number
A78209
Product name
3-Aminopyridine
Purity
99%
Packaging
100g
Price
$57.6
Updated
2024/03/01
TCI Chemical
Product number
A0413
Product name
3-Aminopyridine
Purity
>99.0%(GC)(T)
Packaging
25g
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
A0413
Product name
3-Aminopyridine
Purity
>99.0%(GC)(T)
Packaging
100g
Price
$96
Updated
2024/03/01
Alfa Aesar
Product number
A13216
Product name
3-Aminopyridine, 99%
Packaging
50g
Price
$34.65
Updated
2024/03/01
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3-Aminopyridine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,

Uses

3-Aminopyrodine is also used as an intermediate for agrochemicals, pharmaceuticals and colorants. These are involved in photosensitizer chemistry, luminescent materials, metal complex chemistry and liquid crystal. Aminopyridine is used as a monomer for polymerization. It is also used in the Production of cationic dyes and Apa amoxicillin sodium raw materials.

Uses

manufacture of pharmaceuticals and dyes.

Synthesis Reference(s)

Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2
The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047

Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.]

3-Aminopyridine Preparation Products And Raw materials

Raw materials

Nicotinamide Potassium hydroxide Lead tetraacetate tert-Butanol Aluminum oxide

Preparation Products

2,6-Dichloropyridin-3-amine 1,5-NAPHTHYRIDINE-2-CARBOXYLICACID 2,6-Dibromopyridin-3-amine 3-IODO-2-NITROPYRIDINE 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE N-(4-FORMYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE TERT-BUTYL 4-FORMYLPYRIDIN-3-YLCARBAMATE Pirenzepine 3-Iodopyridine 3-HYDRAZINOPYRIDINE Dihydrochloride
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View Lastest Price from 3-Aminopyridine manufacturers

Hebei Duling International Trade Co. LTD
Product
3-Aminopyridine 462-08-8
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2023-03-03
Dideu Industries Group Limited
Product
3-Aminopyridine 462-08-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-29
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-Aminopyridine 462-08-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

462-08-8, 3-AminopyridineRelated Search:

Acetaminophen 3-Amino-2-bromopyridine 3-Amino-2-pyridinecarboxylic acid 2-Chloro-3-cyanopyridine 2-CHLORO-3,5-DINITROPYRIDINE 3,4-Diaminopyridine 2-CHLORO-3-NITROPYRIDINE 2-Amino-5-nitropyridine 2-(2-AMINOETHYLAMINO)-5-NITROPYRIDINE 2-Methoxy-5-nitropyridine 2-methoxy-5-aminopyridine 5-Amino-2-chloropyridine 3-Amino-2-Chloropyridine 2-Chloro-3-Aminopyridine (3alpha)-3-chloro-Cholest-4-ene 4-Dimethylaminopyridine 2-Chloro-5-nitropyridine 4-Aminopyridine;4-AP; Pyridin-4-amine,4-Aminopyridine (RTC is agent for this item in Europe) 2-Aminopyridine

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  • 462-08-8
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