N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
- Product Name
- N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
- CAS No.
- 312917-14-9
- Chemical Name
- N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
- Synonyms
- CS-320;JNK-5A;SC-20267;SC-202671;TCS JNK 5a;F0016-0404;SC-202671, >98%;TCS JNK 5a, >98%;JNK Inhibitor IX;JNK Inhibitor IX, >=98%
- CBNumber
- CB52518872
- Molecular Formula
- C20H16N2OS
- Formula Weight
- 332.42
- MOL File
- 312917-14-9.mol
N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Property
- Melting point:
- 88-90oC
- Boiling point:
- 486.8±45.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
- form
- Tan solid
- pka
- 11.95±0.20(Predicted)
- color
- Off-white
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 420136
- Product name
- JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem
- Packaging
- 5mg
- Price
- $245
- Updated
- 2024/03/01
- Product number
- 15624
- Product name
- JNK Inhibitor IX
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 15624
- Product name
- JNK Inhibitor IX
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 15624
- Product name
- JNK Inhibitor IX
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $225
- Updated
- 2024/03/01
- Product number
- 15624
- Product name
- JNK Inhibitor IX
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $419
- Updated
- 2024/03/01
N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Chemical Properties,Usage,Production
Description
JNK inhibitor IX (312917-14-9) inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38α and a panel of 30 other kinases.1?Induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.2
Uses
JNK Inhibitor IX is a potent and selective inhibitor of JNK2 and JNK3. Neuroresearch & Neuroprotective Product.
Definition
ChEBI: N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-naphthalenecarboxamide is a naphthalenecarboxamide.
storage
Store at RT
References
1) Angell?et al. (2007),?N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3; Med. Chem. Lett.,?17?1296 2) Jang?et al.?(2014),?Inhibition of JNK2 and JNK3 by JNK inhibitor IX induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells?; Biochem. Biophys. Res. Commun.,?452?845
N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide manufacturers
- Product
- N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide 312917-14-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%~99%
- Supply Ability
- per week 100kg
- Release date
- 2019-09-05