ZLJ-6
- Product Name
- ZLJ-6
- CAS No.
- 1051931-39-5
- Chemical Name
- ZLJ-6
- Synonyms
- ZLJ-6;ZLJ-6 Exclusive;QEJPXTVPNIOEHZ-VEZAGKLZSA-N
- CBNumber
- CB52592894
- Molecular Formula
- C13H17N3O6S2
- Formula Weight
- 375.421
- MOL File
- 1051931-39-5.mol
ZLJ-6 Property
- storage temp.
- Store at -20°C
- solubility
- ≤10mg/ml in DMSO;10mg/ml in dimethyl formamide
- form
- crystalline solid
N-Bromosuccinimide Price
- Product number
- 13271
- Product name
- ZLJ-6
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 13271
- Product name
- ZLJ-6
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 13271
- Product name
- ZLJ-6
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $302
- Updated
- 2024/03/01
- Product number
- 13271
- Product name
- ZLJ-6
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $660
- Updated
- 2024/03/01
- Product number
- C4357
- Product name
- ZLJ-6
- Packaging
- 25mg
- Price
- $753
- Updated
- 2021/12/16
ZLJ-6 Chemical Properties,Usage,Production
Description
ZLJ-
in vitro
zlj-6 was identified as a potent inhibitor of cyclooxygenase in human whole blood. it also inhibited the production of thromboxane b(2) and prostaglandin e(2) in calcium ionophore a23187-induced human and rat whole blood, and rat peritoneal leukocytes. zlj-6 suppressed the activity of 5-lipoxygenase in the rat basophilic leukemia (rbl-1) cell lysate and in intact cells and reduced the generation of leukotriene b(4) (ltb(4)) in a23187-stimulated human or rat whole blood, and rat peritoneal leukocytes [1].
in vivo
orally administered zlj-6 demonstrated potent anti-inflammatory activity in the carrageenin-induced paw oedema model in rats and showed analgesic activity in the acetic acid-induced abdominal construction model in mice. no gastrointestinal ulcers were found with the anti-inflammatory dose (30 mg/kg) in normal rats [1].
IC 50
0.73, 0.31, and 0.99 μm for cox-1, cox-2, and 5-lo, respectively
References
[1] li, l. ,ji, h.,sheng, l., et al. the anti-inflammatory effects of zlj-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. european journal of pharmacology 607 (1-3), 244-250 (2009).
ZLJ-6 Preparation Products And Raw materials
Raw materials
Preparation Products
ZLJ-6 Suppliers
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