D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-

Product Name: D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-
CAS No.: 898537-18-3
Chemical Name: D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-
Synonyms: TS-71;TS 071;(Lusefi);Luseogliflozin;TS 071; TS071; TS-71;Luseogliflozin USP/EP/BP;Tributyl Acetylcitrate Impurity 19;(1S)-1,5-Dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-D-glucitol;D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-;(2S,3R,4R,5S,6R)-2-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-6-(hydroxymethyl)thiane-3,4,5-triol
CBNumber: CB52627756
Molecular Formula: C23H30O6S
Formula Weight: 434.55
MOL File: 898537-18-3.mol

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D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Property

Melting point:: 155.0-157.0℃
Boiling point:: 624.5±55.0 °C(Predicted)
Density: 1.278±0.06 g/cm3(Predicted)
pka: 13.25±0.70(Predicted)
form: Solid
color: White to off-white
InChIKey: WHSOLWOTCHFFBK-ZQGJOIPISA-N
SMILES: [C@H]1(S[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C1=CC(CC2=CC=C(OCC)C=C2)=C(C)C=C1OC

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: L474950
Product name: Luseogliflozin
Packaging: 10mg
Price: $15490
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0012856
Product name: (1S)-1,5-DIDEOXY-1,5-EPITHIO-1-C-[5-[(4-ETHOXYPHENYL)METHYL]-2-METHOXY-4-METHYLPHENYL]-D-GLUCITOL
Purity: 95.00%
Packaging: 10G
Price: $1712.87
Updated: 2021/12/16

Crysdot

Product number: CD12013602
Product name: Luseogliflozin
Purity: 95+%
Packaging: 100mg
Price: $2183
Updated: 2021/12/16

Crysdot

Product number: CD12013602
Product name: Luseogliflozin
Purity: 95+%
Packaging: 25mg
Price: $872
Updated: 2021/12/16

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D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Chemical Properties,Usage,Production

Uses

Luseogliflozin is used n biological studies as a potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycemic activity.

Definition

ChEBI: Luseogliflozin is a diarylmethane.

in vivo

Luseogliflozin (10 mg/kg, oral, 7 days) improves hyperglycemia and promotes β-cell proliferation in mice^[2].

Animal Model:	C57BL/6J male mice induced by OSI-906^[2]
Dosage:	10 mg/kg/daily, 7 days
Administration:	Oral
Result:	Inhibited SGLT2 and significantly improved hyperglycemia in mice, but did not improve hyperinsulinemia.Had no effect on hepatic steatosis and adipose tissue atrophy, and improved the quality and proliferation of β cells.

IC 50

SGLT2: 2.26 nM (IC₅₀); SGLT1: 3990 nM (IC₅₀)

D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Preparation Products And Raw materials

Raw materials

Preparation Products

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D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Suppliers

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View Lastest Price from D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- manufacturers

Wuhan JiyunZen Tech Co., Ltd.

Product: Luseogliflozin Hydrate 898537-18-3
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-06-05

898537-18-3, D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-Related Search:

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Luseogliflozin,D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-

D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-

Luseogliflozin

(1S)-1,5-Dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-D-glucitol

TS 071

(2S,3R,4R,5S,6R)-2-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-6-(hydroxymethyl)thiane-3,4,5-triol

TS 071; TS071; TS-71

TS-71

(Lusefi)

Luseogliflozin USP/EP/BP

D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- USP/EP/BP

Tributyl Acetylcitrate Impurity 19

898537-18-3

C23H30O6S