2-Methoxy-4-pyridinecarboxylic acid
- Product Name
- 2-Methoxy-4-pyridinecarboxylic acid
- CAS No.
- 105596-63-2
- Chemical Name
- 2-Methoxy-4-pyridinecarboxylic acid
- Synonyms
- Zinc00336011;2-methoxy-4-picolinic acid;2-METHOXYISONICOTINIC ACID;2-METHOXYISONICOTONIC ACID;2-MethoxyisonicotinicAcid>2-Methoxypyridine-4-carboxyL;2-Methoxyisonicotinic acid 98%;2-Methoxy-4-pyridinecarboxylicaci;2-Methoxypyridin-4-carboxylic acid;2-METHOXY-4-PYRIDINECARBOXYLIC ACID
- CBNumber
- CB5292271
- Molecular Formula
- C7H7NO3
- Formula Weight
- 153.14
- MOL File
- 105596-63-2.mol
2-Methoxy-4-pyridinecarboxylic acid Property
- Melting point:
- 198-200 °C
- Boiling point:
- 383.0±22.0 °C(Predicted)
- Density
- 1.284±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 4.50±0.10(Predicted)
- form
- Solid or Crystalline Powder
- color
- White to pale brown
- InChI
- InChI=1S/C7H7NO3/c1-11-6-4-5(7(9)10)2-3-8-6/h2-4H,1H3,(H,9,10)
- InChIKey
- DPNDWFVORIGXQO-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC=CC(C(O)=O)=C1
- CAS DataBase Reference
- 105596-63-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-36
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 703680
- Product name
- 2-Methoxypyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $57
- Updated
- 2023/06/20
- Product number
- M2079
- Product name
- 2-Methoxyisonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $31
- Updated
- 2025/07/31
- Product number
- M2079
- Product name
- 2-Methoxyisonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $92
- Updated
- 2025/07/31
- Product number
- M263458
- Product name
- 2-Methoxyisonicotinic Acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- M263458
- Product name
- 2-Methoxyisonicotinic Acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
2-Methoxy-4-pyridinecarboxylic acid Chemical Properties,Usage,Production
Uses
2-Methoxy-4-pyridinecarboxylic acid is often used as an intermediate in pharmaceutical chemistry and organic synthesis. In organic synthesis transformation, the carboxyl group on the pyridine ring can be converted into acyl chloride, ester group and amide under certain reaction conditions without being affected by the pyridine ring, and can also be reduced to a hydroxyl group.
Synthesis
15855-06-8
105596-63-2
General procedure for the synthesis of 2-methoxy-4-pyridinecarboxylic acid from 2-chloro-6-methoxyisonicotinic acid: To a suspension of acetonitrile (150 mL) containing 2-methoxy-4-pyridinecarboxylic acid (1.94 g, 6.49 mmol) was added sodium iodide (4.90 g, 32.69 mmol) and trimethylmethylsilyl chloride (4.10 mL, 32.42 mmol). The reaction mixture was stirred at 40 °C for 3 days under nitrogen protection. After completion of the reaction, the mixture was cooled to 0 °C, the solid product was collected by filtration, washed with acetonitrile and dried to afford 1.66 g (90% yield) of the target compound, 2-methoxy-4-pyridinecarboxylic acid.LRMS: m/z 285 (M + 1)+; retention time: 2.86 min (Method B).
References
[1] Patent: WO2010/43377, 2010, A1. Location in patent: Page/Page column 64
[2] Yakugaku Zasshi, 1953, vol. 73, p. 845,846, 847
[3] Chem.Abstr., 1954, p. 10021
[4] Yakugaku Zasshi, 1953, vol. 73, p. 845,846, 847
[5] Chem.Abstr., 1954, p. 10021
2-Methoxy-4-pyridinecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methoxy-4-pyridinecarboxylic acid Suppliers
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
View Lastest Price from 2-Methoxy-4-pyridinecarboxylic acid manufacturers
- Product
- 2-Methoxy-4-pyridinecarboxylic acid 105596-63-2
- Price
- US $10.00-8.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-06
- Product
- 2-Methoxy-4-pyridinecarboxylic acid 105596-63-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-25
- Product
- 2-Methoxy-4-pyridinecarboxylic acid 105596-63-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24