Isoconazole nitrate

Product Name: Isoconazole nitrate
CAS No.: 24168-96-5
Chemical Name: Isoconazole nitrate
Synonyms: Fazol;R 15454;Travogyn;Travogen;Adestan G 100;Gyno-Travogen;Gyno-travozen;ISOCONAZOLE NITRATE;IsoconazoleNitrate>Isosorbide itraconazole
CBNumber: CB5317271
Molecular Formula: C18H15Cl4N3O4
Formula Weight: 479.14
MOL File: 24168-96-5.mol

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Isoconazole nitrate Property

Melting point:: 178-182°C
storage temp.: Sealed in dry,2-8°C
solubility: Very slightly soluble in water, soluble in methanol, slightly soluble in ethanol (96 per cent).
form: Solid
color: White to Off-White
Merck: 14,5160
CAS DataBase Reference: 24168-96-5(CAS DataBase Reference)

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Safety

RTECS: NI4772000
HS Code: 2933.29.4300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2232
Product name: Econazole Impurity D
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 500MG
Price: $143
Updated: 2024/03/01

Sigma-Aldrich

Product number: I0380000
Product name: Isoconazole nitrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: i0380000
Price: $153
Updated: 2024/03/01

TCI Chemical

Product number: I0834
Product name: Isoconazole Nitrate
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $88
Updated: 2024/03/01

TCI Chemical

Product number: I0834
Product name: Isoconazole Nitrate
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $222
Updated: 2022/04/27

Cayman Chemical

Product number: 30100
Product name: Isoconazole (nitrate)
Packaging: 1g
Price: $44
Updated: 2024/03/01

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Isoconazole nitrate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Fazol,Fournier,France,1979

Uses

Antibacterial; antifungal

Uses

Isoconazole Nitrate acts as an antibacterial in the local treatment of vaginitis; antifungal agent (1,2).

Manufacturing Process

To a stirred and refluxing solution of 40 parts of benzene and 35 parts of dimethylformamide (both solvents previously dried azeotropically) are added successively 1.6 parts of sodium hydride and 7.7 parts of α-(2,4- dichlorophenyl)imidazole-1-ethanol, (cooling on ice is necessary). After the addition is complete, stirring and refluxing is continued for 30 minutes. Then there are added 7.8 parts of 2.6-dichlorobenzyl chloride and the whole is stirred at reflux for another 3 hours. The reaction mixture is poured onto water and the product 1-[2,4-dichloro-b-(2,6-dichlorobenzyloxy)phenethyl] imidazole, is extracted with benzene. The extract is washed twice with water, dried, filtered and evaporated in vacuo. The base residue is dissolved in a mixture of acetone and diisopropyl ether and to this solution is added an excess of concentrated nitric acid solution. The precipitated nitrate salt is filtered off and recrystallized from a mixture of methanol and diisopropyl ether, yielding 1-[2,4-dichloro-b-(2,6-dichlorobenzyloxy)phenethyl]imidazole nitrate; melting point 179°C.

Therapeutic Function

Antibacterial, Antifungal

Isoconazole nitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Isoconazole nitrate Suppliers

Americas 1 Canada 1 China 183 Europe 3 France 1 Germany 2 India 8 Italy 1 Japan 1 United Kingdom 4 United States 26 Global 231

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View Lastest Price from Isoconazole nitrate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Isoconazole Nitrate 24168-96-5
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-21

Career Henan Chemical Co

Product: Isoconazole nitrate 24168-96-5
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-22

24168-96-5, Isoconazole nitrate Related Search:

(Trifluoromethoxy)benzene Miconazole nitrate Ethanol Ethyl acetate 4-Methoxyphenylacetone Ethylparaben Ethyl cyanoacetate NITRATE Thiamine nitrate p-Anisidine ISOXADIFEN-ETHYL p-(2-Methoxyethyl) phenol Econazole nitrate Dichlorodiphenylsilane Miconazole Nitrate Methoxydiethylborane Dichloromethylphenylsilane Anisole

1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1h-imidazole mononitrate

1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazolium nitrate

1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-, mononitrate (9CI)

Adestan G 100

Fazol

Gyno-Travogen

Imidazole, 1-[2,4-dichloro-b-[(2,6-dichlorobenzyl)oxy]phenethyl]-, mononitrate (8CI)

R 15454

Travogen

Travogyn

ISOCONAZOLE NITRATE

1-(2-(2,4-Dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)-1H-imidazole nitrate

1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)Methoxy]ethyl]-iMidazole Mononitrate

1-[2-(2,6-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole Nitrate

1h-imidazole-1-acetamide, 5-ethyl-n-methyl-2-nitro-

Gyno-travozen

Isosorbide itraconazole

1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole, nitrate (1:1)

Isoconazole nitrate CRS

IsoconazoleNitrate&gt

Isoconazole nitrate USP/EP/BP

TIANFU Isoconazole nitrate

Miconazole EP Impurity D as Nitrate

Miconazole Nitrate EP Impurity D as Nitrate

1-(2-((2,6-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate

Isoconazole Nitrate, ≥ 98.0%

24168-96-5

168-96-5

C18H14Cl4N2OHNO3C18H15Cl4N3O4

C18H14Cl4N20HNO3

Inhibitors

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Antifungal