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CP671305

Product Name
CP671305
CAS No.
445295-04-5
Chemical Name
CP671305
Synonyms
CS-2886;CP671305;UNII-9LH034R9R9;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
CBNumber
CB53175535
Molecular Formula
C23H19FN2O7
Formula Weight
454.4
MOL File
445295-04-5.mol
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CP671305 Property

storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
10mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
5mg
Price
$193
Updated
2024/03/01
ChemScene
Product number
CS-6774
Product name
CP671305
Purity
99.95%
Packaging
25mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
BC161230
Product name
CP 671305
Packaging
2mg
Price
$250
Updated
2021/12/16
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CP671305 Chemical Properties,Usage,Production

Description

CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.

CP671305 Preparation Products And Raw materials

Raw materials

Preparation Products

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CP671305 Suppliers

China 32 United Kingdom 1 United States 6 Global 39
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

445295-04-5, CP671305Related Search:

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE 4-Chloro-N,N-diethylbenzaMide, 97% 4-Chloro-N,N-di-n-propylbenzaMide, 97% TIMTEC-BB SBB006342 NSC781406 2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]- 4-Chloro-N,N-diisopropylbenzamide Pifithrin-μ 2-Pyridinecarbothioamide, N-2-pyridinyl- 1,3-Bis(4-aminophenyl)urea 5-(4-iodobenzylidene)rhodanine S3I-201 NSC228155 NSC632839hydrochloride NSC23005 Sodium HAMNO NSC 247030 NSC 42834

  • CP671305
  • CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5
  • UNII-9LH034R9R9
  • CS-2886
  • Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
  • (R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid
  • CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit
  • 445295-04-5
  • API