ChemicalBook > CAS DataBase List > 2-Chloroquinoline

2-Chloroquinoline

Product Name
2-Chloroquinoline
CAS No.
612-62-4
Chemical Name
2-Chloroquinoline
Synonyms
2CQ;2-chloro-quinolin;2-CHLOROQUINOLINE;Quinoline2-chloro-;2-Chloroquinoline,99%;2-Chloroquinoline >2-Chloroquinoline, 98%+;2-Chloroquinoline ,99.70%;2-Chloroquinoline, 99% 5GR;2-Chloroquinoline, 99% 1GR
CBNumber
CB5403688
Molecular Formula
C9H6ClN
Formula Weight
163.6
MOL File
612-62-4.mol
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2-Chloroquinoline Property

Melting point:
34-37 °C (lit.)
Boiling point:
266-267 °C (lit.)
Density 
1.23 g/mL at 25 °C (lit.)
refractive index 
1.6342 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
methanol: 0.1 g/mL, clear
form 
Crystalline Powder, Crystals and/or Chunks or Fused Mass
pka
0.41±0.40(Predicted)
color 
White to yellow
Water Solubility 
Insoluble
BRN 
112561
InChIKey
OFUFXTHGZWIDDB-UHFFFAOYSA-N
CAS DataBase Reference
612-62-4(CAS DataBase Reference)
NIST Chemistry Reference
Quinoline, 2-chloro-(612-62-4)
EPA Substance Registry System
Quinoline, 2-chloro- (612-62-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
VB2320000
F 
8
TSCA 
Yes
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C70401
Product name
2-Chloroquinoline
Purity
99%
Packaging
5g
Price
$147.6
Updated
2024/03/01
Sigma-Aldrich
Product number
C70401
Product name
2-Chloroquinoline
Purity
99%
Packaging
1g
Price
$89.5
Updated
2023/06/20
TCI Chemical
Product number
C0282
Product name
2-Chloroquinoline
Purity
>98.0%(GC)
Packaging
5g
Price
$66
Updated
2024/03/01
TCI Chemical
Product number
C0282
Product name
2-Chloroquinoline
Purity
>98.0%(GC)
Packaging
25g
Price
$262
Updated
2024/03/01
Alfa Aesar
Product number
B23443
Product name
2-Chloroquinoline, 99%
Packaging
25g
Price
$252
Updated
2021/12/16
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2-Chloroquinoline Chemical Properties,Usage,Production

Chemical Properties

white to yellowish crystals, powder, chunks or

Uses

2-Chloroquinoline is an intermediate used in the synthesis of various compounds that exhibits antifungal properties.

Uses

2-Chloroquinoline is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It reacts with benzotriazole, followed by cyclization with loss of nitrogen, gives the indolo[2,3-b]quinoline ring system for use in novel cytotoxic DNA topoisomerase II inhibitors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196i
Synthesis, p. 1013, 1987 DOI: 10.1055/s-1987-28152

Purification Methods

Purify it by crystallisation of its picrate to constant melting point (123-124o) from *benzene, regenerating the base and distilling it under vacuum [Cumper et al. J Chem Soc 1183 1962]. 2-Chloroquinoline can be crystallised from EtOH. Its picrate has m 123-124o (from EtOH). [Beilstein 20 H 359, 20/7 V 312.]

2-Chloroquinoline Preparation Products And Raw materials

Raw materials

Quinoline Ethanol Acetic anhydride N,N-Dimethylformamide Cesium carbonate Hydrogen peroxide Toluene Acetyl chloride Trichloroisocyanuric acid Phosphorus oxychloride Triethylamine 2-Quinolinol 1,4-Dioxane Tosyl chloride Phosphorus trichloride Benzene N-Chlorosuccinimide Ethyl acetate 2-Aminobenzaldehyde Hydrochloric acid Acetic acid Triphenylphosphine Pyridine

Preparation Products

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2-Chloroquinoline Suppliers

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View Lastest Price from 2-Chloroquinoline manufacturers

Henan Fengda Chemical Co., Ltd
Product
Chloroquinoline 612-62-4
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Henan Aochuang Chemical Co.,Ltd.
Product
2-Chloroquinoline 612-62-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27
Hebei Zhanyao Biotechnology Co. Ltd
Product
2-Chloroquinoline 612-62-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-14

612-62-4, 2-ChloroquinolineRelated Search:

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