Nandrolone
- Product Name
- Nandrolone
- CAS No.
- 434-22-0
- Chemical Name
- Nandrolone
- Synonyms
- 19-NORTESTOSTERONE;nortestosterone;NANDROLON;Nandrolone Base;NADROLONE;Nandrolone decanoat;C07254;NSC 3351;ndrolone;menidrabol
- CBNumber
- CB5681525
- Molecular Formula
- C18H26O2
- Formula Weight
- 274.4
- MOL File
- 434-22-0.mol
Nandrolone Property
- Melting point:
- 120-125 °C
- alpha
- D22 +55° (c = 0.93 in chloroform)
- Boiling point:
- 357.38°C (rough estimate)
- Density
- 1.0528 (rough estimate)
- refractive index
- 1.4800 (estimate)
- Flash point:
- 2℃
- storage temp.
- Controlled Substance, -20°C Freezer
- solubility
- Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
- form
- A crystalline solid
- pka
- 15.06±0.40(Predicted)
- color
- Dimorphic crystals from CH2Cl2/Et2O
- Water Solubility
- 3.09g/L(25 ºC)
- Merck
- 6365
- BRN
- 2055849
- InChIKey
- NPAGDVCDWIYMMC-IZPLOLCNSA-N
- CAS DataBase Reference
- 434-22-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Nandrolone(434-22-0)
Safety
- Hazard Codes
- Xn,T,F
- Risk Statements
- 20/21/22-64-40-61-60-36-11-38-19
- Safety Statements
- 22-24/25-36/37/39-45-36/37-53-16
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- RTECS
- KG7964000
- HS Code
- 29372900
- Hazardous Substances Data
- 434-22-0(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- N-050
- Product name
- Nandrolone solution
- Purity
- 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $170
- Updated
- 2024/03/01
- Product number
- BP257
- Product name
- Nandrolone
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $255
- Updated
- 2024/03/01
- Product number
- 1454008
- Product name
- Nandrolone
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 50mg
- Price
- $953
- Updated
- 2024/03/01
- Product number
- 21173
- Product name
- Nandrolone
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $38
- Updated
- 2024/03/01
- Product number
- 21173
- Product name
- Nandrolone
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
Nandrolone Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Originator
Durabolin,Organon,US,1959
Uses
An anabolic steroid. Controlled substance (anabolic steroid)
Definition
ChEBI: A 3-oxo Delta4-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17.
Manufacturing Process
An ice-cold solution of 1.5 grams of 19-nortestosterone and 1.5 ml of dry pyridine in 10 ml of dry benzene is prepared and a solution of 1.5 ml of β- phenylpropionyl chloride in 5 ml of dry benzene is added dropwise over a period of about 2 minutes with stirring. The resulting mixture is allowed to stand overnight under an atmosphere of nitrogen and then washed successively with cold 5% aqueous hydrochloric acid solution, cold 2.5% aqueous sodium hydroxide solution, and water. After drying over anhydrous sodium sulfate, the solvent is evaporated to give an almost colorless oil. Recrystallization from methanol gives white crystals of 19-nortestosterone 17- β-phenylpropionate, MP 91° to 92.5°C.
Therapeutic Function
Anabolic
Mechanism of action
Nandrolone facilitates formation of body muscle mass and strengthens the process of osseous tissue development. The main indications for using nandrolone, as well as other anabolic steroids, are abnormal protein anabolism, asthenia, diseases accompanied by protein loss, adrenal insufficiency, steroid diabetes, and prolonged condition of sluggishness.
Safety Profile
Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.
Synthesis
Nandrolone, 17|?-hydroxyester-4-en-3-one (29.1.7), is made from estradiol (28.1.17). The phenol hydroxyl group undergoes methylation by dimethylsulfate in the presence of sodium hydroxide, forming the corresponding methyl ether (29.3.1), and then the aromatic ring is reduced by lithium in liquid ammonia, which forms an enol ether (29.3.2). Hydrolyzing this compound with a mixture of hydrochloric and acetic acids leads to the formation of a keto group, and simultaneous isomerization of the double bond from C5¨CC10 to position C4¨CC5 gives the desired nandrolone (29.3.3) [16¨C19]. Upon necessity of using it in the form of acid esters, the product is acylated by corresponding acid derivatives.
Nandrolone Preparation Products And Raw materials
Raw materials
Preparation Products
Nandrolone Suppliers
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- United Kingdom
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View Lastest Price from Nandrolone manufacturers
- Product
- Nandrolone base 434-22-0
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-16
- Product
- Nandrolone 434-22-0
- Price
- US $230.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2023-04-04
- Product
- Nandrolone 434-22-0
- Price
- US $25.00/Box
- Min. Order
- 1Box
- Purity
- 99.99%
- Supply Ability
- 10000000000
- Release date
- 2023-12-05