Azamethiphos

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Description References

Product Name: Azamethiphos
CAS No.: 35575-96-3
Chemical Name: Azamethiphos
Synonyms: PHOSPHOROTHIOATE;azametifos;Azametiphos;AZAMETHIFOS;snip;SNIP(R);GS 40616;ALFACRON;SNIP(TM);cga18809
CBNumber: CB5687123
Molecular Formula: C9H10ClN2O5PS
Formula Weight: 324.68
MOL File: 35575-96-3.mol

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Azamethiphos Property

Melting point:: 88-93°C
Boiling point:: 428.8±55.0 °C(Predicted)
Density: 1.566±0.06 g/cm3(Predicted)
vapor pressure: 4.9 x 10^-6 Pa (20 °C)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
Water Solubility: 1100 mg l^-1 (20 °C)
pka: 0.94±0.20(Predicted)
color: White to off-white
CAS DataBase Reference: 35575-96-3(CAS DataBase Reference)
NIST Chemistry Reference: Phosphorothioic acid, s-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2h)-yl)methyl] o,o-dimethyl ester(35575-96-3)
EPA Substance Registry System: Azamethiphos (35575-96-3)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36-40-21-67-36/37/38
Safety Statements: 26-36/37-24/25-23
RIDADR: UN 1593 6.1/PG 3
WGK Germany: 3
RTECS: TE8070000
HS Code: 29349990
Toxicity: LD50 orl-rat: 1180 mg/kg PEMNDP 9,44,91

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H331Toxic if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 45331
Product name: Azamethiphos
Purity: PESTANAL
Packaging: 250mg
Price: $67.3
Updated: 2024/03/01

Alfa Aesar

Product number: H66105
Product name: S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95%
Packaging: 1g
Price: $81.3
Updated: 2023/06/20

Alfa Aesar

Product number: H66105
Product name: S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95%
Packaging: 5g
Price: $332
Updated: 2021/12/16

Alfa Aesar

Product number: H66105
Product name: S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95%
Packaging: 250mg
Price: $27.1
Updated: 2023/06/20

TRC

Product number: A801300
Product name: Azamethiphos
Packaging: 1g
Price: $65
Updated: 2021/12/16

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Azamethiphos Chemical Properties,Usage,Production

Description

Azamethiphos is an organothiophosphate insecticide. It can be used as a veterinary drug used in the salmon fish farming for controlling parasites such as salmon lice (Lepeophtheirus salmonis), a marine ectoparasitic copepod on salmonid species. Its primary target is on the acetylcholinesterase, a serine hydrolase involved in neurotransmission at cholinergic synapses and neuromuscular junctions.

References

Intorre, L, et al. "Safety of azamethiphos in eel, seabass and trout." Pharmacological Research the Official Journal of the Italian Pharmacological Society 49.2(2004):171. Kaur, K, et al. "Mechanism behind Resistance against the Organophosphate Azamethiphos in Salmon Lice (Lepeophtheirus salmonis). " Plos One 10.4(2015):e0124220.

Chemical Properties

white to light yellow crystal powde

Uses

Azamethiphos is used to control flies and other insect pests in animal houses and also public hygiene and health pests such as mosquitoes and cockroaches. It has recently been used to control sea lice in salmon.

Uses

Synergistic insecticidal and acaricidal organophosphorus compound

Definition

ChEBI: Azamethiphos is an organic thiophosphate, an organothiophosphate insecticide, an organochlorine insecticide and an organochlorine acaricide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an agrochemical. It is functionally related to an oxazolo[4,5-b]pyridin-2(3H)-one.

Safety Profile

Moderately toxic by ingestion andskin contact. When heated to decomposition it emits toxicvapors of NOx, SOx, POx, and Cl^- .

Metabolic pathway

Azamethiphos is metabolised in mammals via hydrolysis, followed by opening of the oxazolinone ring and conjugation of the resultant aminopyridinol as the glucuronide and sulfate ester.

Metabolism

Azamethiphos is metabolized via the cleavage of phosphorothiolate C?S bond, followed by N-demethylation and opening of the oxazolinone ring and conjugation of the resultant aminochloropyridinol as the glucuronide and sulfate ester.

Toxicity evaluation

Acute oral LD₅₀ for rats is 1180 mg/kg. Inhalation LC50 (4 h) for rats is >560 mg/m3 air. ADI is 0.025 mg/kg.

Degradation

Azamethiphos is unstable in alkalis and acids. The DT₅₀ values at pH 5,7 and 9 were 800,260 and 4.3 hours, respectively (PM).

Azamethiphos Preparation Products And Raw materials

Raw materials

Sulfur Thio ammonium salt formaldehyde Chlorine Dimethyl sulfide Oxazole Dimethyl phosphite

Preparation Products

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Azamethiphos Suppliers

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View Lastest Price from Azamethiphos manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Azamethiphos 35575-96-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-24

Hebei Chuanghai Biotechnology Co,.LTD

Product: Azamethiphos 35575-96-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.8%
Supply Ability: 100tons
Release date: 2024-08-12

Hebei Mojin Biotechnology Co.,Ltd

Product: Azamethiphos 35575-96-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-08-21

35575-96-3, AzamethiphosRelated Search:

Zoledronic acid Zoledronic acid hydrate 3-Chloro-5-methoxypyridine Phenol, 2,4,5-trichloro-, O-ester with O,O-dimethyl phosphorothioate O-(2-Diethylamino-6-methylpyrimidin-4-yl) O,O-dimethyl phosphorothioate ),)-dimethylo,o-[3-methyl-4-(methylthio)phenyl]phosphorothioat O,O-Diethyl O-[p-(Methylsulfinyl)phenyl] phosphorothioate,o,o-diethylo-(4-(methylsulfinyl)phenyl)phosphorothioate[qr Azamethiphos-D-6 O,O-Diethyl O-2,5-dichloro-4-bromophenyl-phosphorothioate,o,o-diethylo-2,5-dichloro-4-bromophenyl-phosphorothioat O,O-Dimethyl S-1,2-bis(ethoxycarbonyl)ethyl phosphorothioate,Diethyl mercaptosuccinate S-ester with O,O-dimethyl phosphorothioate Temephos o,o-diethyls-(2-eththioethyl)phosphorothioat 5-Chloro-3-pyridinol 2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one Azamethiphos 2-Amino-3-methoxypyridine o,o-diethylo-(4-methyl-7-coumarinyl)phosphorothioat o,o,-dimethylo-(4-cyanophenyl)phosphorothioat

6-Chloro-3-(dimethoxyphosphorylsulfanylmethyl)-[1,3]oxazolo[4,5-b]pyridin-2-one

Phosphorothioic acid, S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl ester

Alfracron

GS 40616

O，O-dimethyl-S-[6-chloro-2-oxooxazolo [4,5-b] pyridin-3 (2H)-yl] methyl phosphorothionate

Thiophosphoric acid S-(6-chloro-2-oxo-2,3-dihydrooxazolo[4,5-b]pyridin-3-ylmethyl)O,O-dimethyl ester

Thiophosphoric acid S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl]O,O-dimethyl ester

Azamethiphos 100ug/ml in Methylene chloride 5ml [35575-96-3]

Azamethiphos (100ug/ml in Methylene chloride)

ciba-geigy18809

o,o-dimethylester

phosphorothioicacid,s-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2h)-yl)methyl)

s-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2h)-yl)methyl)o,o-dimethylphosphor

s-(6-chlorooxazolo(4,5-b)pyridin-2(3h)-on-3-ylmethyl)o,o-dimethylphosphorot

snip

AZAMETHIPHOS

ALFACRON

ALFACRON(R)

ALIFICRON(R)

azametifos

Oxazolo(4,5-b)pyridine, phosphorothioic acid deriv.

S-(6-chloro-oxazolo[4,5-b]pyridin-2(3H)-on-3-ylmethyl) O,O-dimethyl phosphorothioate

Azamethiphos 0

Azamethiphos solution

S-((6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl) O,O-dimethyl phosphorothioate

S-6-CHLORO-2,3-DIHYDRO-2-OXO-1,3-OXAZOLO[4.5-B]PYRIDIN-3-YLMETHYL-O,O-DIMETHYLPHOSPHOROTHIOATE

S-6-CHLORO-2,3-DIHYDRO-2-OXO-OXAZOLO-[4,5-B]PYRIDIN-3-YLMETHYL O,O-DIMETHYL

S-6-CHLORO-2,3-DIHYDRO-2-OXO-OXAZOLO[4.5-B]PYRIDIN-3-YLMETHYL-O,O-DIMETHYL PHOSPHOROTHIOATE

S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl thiophosphate

SNIP(R)

SNIP(TM)

PHOSPHOROTHIOATE

5-b)pyridin-2(3h)-on-3-thiophosphorsaeure-o-dimethyl-s-(6-chlor-oxazolo(4

cga18809

AZAMETHIOPHOS PESTANAL

AZAMETHIPHOS PESTANAL, 250 MG

Azamethiphos-Pesticides

Azametiphos

S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-Dimethyl Ester Phosphorothioic Acid

Salmosan

azamethiphos (bsi,iso)

S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate

AZAMETHIFOS

Azamethiphos Solution, 100ppm

SNIP(TM)(100UG/MLINMETHYLENECHLORIDE)

O,O-DIMETHYL-S-(6-CHLORO-OXAZOLO(4,5-B)-PYRIDIN-2(3H)-ONE-3-YL-METHYL)-THIOPHOSPHATE

S-[6-chloro-oxazolo(4,5-b)pyridin-2(3H)-on-yl-methyl]-O,O-dimethyl-phospophorothioate

S-[(6-Chloro-2-oxooxazolo[4,5-β]pyridin-3(2H)-yl)methyl] O,O-Dimethyl Ester Phosphorothioic Acid

5-chloro-3-[(dimethoxyphosphorylthio)methyl]-1,3-benzoxazol-2-one

AZAMETHYPHOS

PHOSPHOROTHIOATE Hot sell

Azamethiphos Standard

Azamethiphos@1000 μg/mL in Methanol

Azamethiphos @100 μg/mL in MeOH

Azamethiphos Solution in Acetone, 100μg/mL

4'-Benzophenonetetracarboxylic dianhydride

Azamethiophos

Azamethiphos CAS 35575-96-3