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H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH

Product Name
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
CAS No.
143413-47-2
Chemical Name
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
Synonyms
(ARG)9;RRRRRRRRR;Peptide R9;R 9 peptide;Nonaarginine;(Arg)9 peptide;H-RRRRRRRRR-NH2;Poly Arginine 9;Nona-L-arginine;R9/Nonaarginine
CBNumber
CB5706464
Molecular Formula
C54H110N36O10
Formula Weight
1423.69
MOL File
143413-47-2.mol
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H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Property

Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
Sequence
H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Aaron Chemicals
Product number
AR009BQF
Product name
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
Purity
97%
Packaging
100mg
Price
$220
Updated
2021/12/16
Aaron Chemicals
Product number
AR009BQF
Product name
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
Purity
97%
Packaging
250mg
Price
$326
Updated
2021/12/16
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H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Chemical Properties,Usage,Production

Biological Activity

(Arg)9 (Nona-L-arginine; Peptide R9) is a cell-permeable polypeptide with IC50 value of 0.78 μM for neuroprotection in a glutamate model experimental model.

in vitro

Poly-arginine (eg (Arg)9) and arginine-rich peptides (eg TAT, penetratin), which belong to a class of peptides with cell-penetrating properties are neuroprotective. It provides significant neuroprotection in a dose–response manner following glutamic acid exposure (IC 50 =0.78 μM). Following kainic acid exposure, (Arg)9 is neuroprotective, but less effective than in the glutamic acid model (IC 50 =0.81 μM). (Arg)9 also shows neuroprotection following in vitro ischemia (IC 50 =6 μM).

in vivo

(Arg)9) (D-isoform) is neuroprotective in rat stroke models. (Arg)9) is highly neuroprotective, with efficacy increasing with increasing arginine content, has the capacity to reduce glutamic acid-induced neuronal calcium influx and requires heparan sulfate preotoglycan-mediated endocytosis to induce a neuroprotective effect. (Arg)9) (D-isoform) administered intravenously at a dose of 1000 nmol/kg 30 min after reduces permanent middle cerebral artery occlusion (MCAO) infarct volume .

target

IC50: 0.78 μM (neuroprotection)

H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH Suppliers

China 68 United States 8 Global 76
MedChemexpress LLC
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sales@medchemexpress.cn
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BOC Sciences
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View Lastest Price from H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH manufacturers

Career Henan Chemical Co
Product
H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH 143413-47-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

143413-47-2, H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OHRelated Search:

GO-203 TAT (48 - 57) K9 D-R9 2-ADAMANTANECARBONYL-ARG-PHE-NH2 TRIFLUOROACETATE LCKLSL HUWENTOXIN IV CALCIUM-LIKE PEPTIDE DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS COG-1410 HNGF6A PHRIXOTOXIN 3 GIP (1-39) H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH (ARG)9, TAMRA-LABELED (ARG)9, FAM-LABELED H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH H-ARG-ARG-ARG-ARG-OH

  • H-RRRRRRRRR-NH2
  • RRRRRRRRR
  • (ARG)9
  • H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
  • Nonaarginine
  • H(-Arg)9-OH, Nonaarginine
  • (Arg)9 peptide
  • Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg
  • Poly Arginine 9|(Arg)9 peptide|RRRRRRRRR
  • Poly Arginine 9|(Arg)9 NJ-Peptide
  • Poly Arginine 9
  • L-Arginine,L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-
  • Nona-L-arginine
  • Peptide R9
  • L-Arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginine
  • R 9 peptide
  • (6S,9S,12S,15S,18S,21S,24S,27S,30S)-1,6-Diamino-9,12,15,18,21,24,27,30-octakis(3-guanidinopropyl)-1-imino-7,10,13,16,19,22,25,28-octaoxo-2,8,11,14,17,20,23,26,29-nonaazahentriacontan-31-oic acid
  • R9/Nonaarginine
  • 143413-47-2
  • C54H110N36O10
  • peptide