PHRIXOTOXIN 3

Product Name: PHRIXOTOXIN 3
CAS No.: 880886-00-0
Chemical Name: PHRIXOTOXIN 3
Synonyms: PHRIXOTOXIN 3
CBNumber: CB14724231
Molecular Formula: C176H269N51O48S6
Formula Weight: 0
MOL File: Mol file

More

Less

PHRIXOTOXIN 3 Property

storage temp.: Store at -20°C
form: Powder
Water Solubility: Soluble to 1 mg/ml in water

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 4914
Product name: Phrixotoxin3
Packaging: 100U
Price: $292
Updated: 2021/12/16

Usbiological

Product number: 256242
Product name: Phrixotoxin 3
Packaging: 100ug
Price: $593
Updated: 2021/12/16

ApexBio Technology

Product number: B5764
Product name: Phrixotoxin3
Packaging: 100ug
Price: $423
Updated: 2021/12/16

More

Less

PHRIXOTOXIN 3 Chemical Properties,Usage,Production

Description

Potent blocker of voltage-gated sodium channels (IC50 values are 0.6, 42, and 72 nM for NaV2, NaV3 and NaV5 respectively). Blocks inward sodium currents in a voltage-dependent manner.

Uses

Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC50s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current[1].

IC 50

Nav1.3: 42 nM (IC₅₀); Nav1.4: 72 nM (IC₅₀); Nav1.5: 610 nM (IC₅₀); Nav1.2: 0.6 nM (IC₅₀); Nav1.1: 288 nM (IC₅₀)

storage

Store at -20°C

References

[1] Bosmans F, et, al. Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Comparative Study Mol Pharmacol. 2006 Feb; 69(2): 419-29. DOI:10.1124/mol.105.015941

PHRIXOTOXIN 3 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PHRIXOTOXIN 3 Suppliers

China 25 Japan 1 United Kingdom 1 United States 4 USA 1 Global 32

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-0571-88211921 19105816207
Email: sales4@gotopbio.com
Country: China
ProdList: 5144
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6979
Advantage: 58

880886-00-0, PHRIXOTOXIN 3Related Search:

PKA Inhibitor Fragment (6-22) amide H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH BeKm 1 antibacterial protein ll-37 amide (human) 2-ADAMANTANECARBONYL-ARG-PHE-NH2 TRIFLUOROACETATE LCKLSL H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH HUWENTOXIN IV CALCIUM-LIKE PEPTIDE DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS COG-1410 GIP (1-39) HNGF6A

PHRIXOTOXIN 3

880886-00-0

C176H269N51O48S6