ChemicalBook > CAS DataBase List > BeKm 1

BeKm 1

Product Name
BeKm 1
CAS No.
524962-01-4
Chemical Name
BeKm 1
CBNumber
CB93343114
Molecular Formula
C174H261N51O52S6
Formula Weight
4091.63464
MOL File
524962-01-4.mol
More
Less

BeKm 1 Property

storage temp. 
Store at -20°C
form 
Solid
color 
White to off-white
Sequence
Arg-Pro-Thr-Asp-Ile-Lys-Cys-Ser-Glu-Ser-Tyr-Gln-Cys-Phe-Pro-Val-Cys-Lys-Ser-Arg-Phe-Gly-Lys-Thr-Asn-Gly-Arg-Cys-Val-Asn-Gly-Phe-Cys-Asp-Cys-Phe (Disulfide bridge:Cys13-Cys33;Cys17-Cys35;Cys7-Cys28)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

BeKm 1 Chemical Properties,Usage,Production

Description

Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart.

Uses

BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease[1].

References

[1] Milnes JT, et al. Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin. FEBS Lett. 2003;547(1-3):20-26. DOI:10.1016/s0014-5793(03)00662-8

BeKm 1 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BeKm 1 Suppliers

Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
15397062932
Email
sales1@gotopbio.com
Country
China
ProdList
2923
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-0571-88211921 19105816207
Email
sales4@gotopbio.com
Country
China
ProdList
5144
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6979
Advantage
58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd.
Tel
0571-85350119 15888826472
Email
15888826472@163.com
Country
China
ProdList
2729
Advantage
58
Shanghai HongTide Biotechnology Co.,Ltd.
Tel
15318089928
Email
alex@hanhonggroup.com
Country
China
ProdList
4604
Advantage
58