BeKm 1

Product Name: BeKm 1
CAS No.: 524962-01-4
Chemical Name: BeKm 1
CBNumber: CB93343114
Molecular Formula: C174H261N51O52S6
Formula Weight: 4091.63464
MOL File: 524962-01-4.mol

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BeKm 1 Property

storage temp.: Store at -20°C
form: Solid
color: White to off-white
Sequence: Arg-Pro-Thr-Asp-Ile-Lys-Cys-Ser-Glu-Ser-Tyr-Gln-Cys-Phe-Pro-Val-Cys-Lys-Ser-Arg-Phe-Gly-Lys-Thr-Asn-Gly-Arg-Cys-Val-Asn-Gly-Phe-Cys-Asp-Cys-Phe (Disulfide bridge:Cys13-Cys33;Cys17-Cys35;Cys7-Cys28)

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Hazard and Precautionary Statements (GHS)

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BeKm 1 Chemical Properties,Usage,Production

Description

Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart.

Uses

BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease[1].

References

[1] Milnes JT, et al. Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin. FEBS Lett. 2003;547(1-3):20-26. DOI:10.1016/s0014-5793(03)00662-8

BeKm 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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BeKm 1 Suppliers

China 21 United Kingdom 1 United States 2 Global 24

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524962-01-4