FMOC-L-ALANINOL
- Product Name
- FMOC-L-ALANINOL
- CAS No.
- 161529-13-1
- Chemical Name
- FMOC-L-ALANINOL
- Synonyms
- FMOC-ALA-OL;(9H-fluoren-9-yl)methyl 1-hydroxypropan-2-ylcarbamate;Fmoc-L-Ala-OL;FMOC-ALANINOL;FMOC-L-ALANINOL;CAS:161529-13-1;Fmoc-DL-Alaninol;N-FMOC-L-ALANINOL;N-Fmoc-L-alaninol,95%;N-ALPHA-FMOC-L-ALANINOL
- CBNumber
- CB5710425
- Molecular Formula
- C18H19NO3
- Formula Weight
- 297.35
- MOL File
- 161529-13-1.mol
FMOC-L-ALANINOL Property
- Melting point:
- 120 °C
- Boiling point:
- 503.9±33.0 °C(Predicted)
- Density
- 1.210±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 11.48±0.46(Predicted)
- form
- Solid
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 161529-13-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F594920
- Product name
- Fmoc-l-alaninol
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 276984
- Product name
- Fmoc-L-alaninol
- Packaging
- 1g
- Price
- $333
- Updated
- 2021/12/16
- Product number
- 03171
- Product name
- Fmoc-L-alaninol
- Purity
- ≥ 99% (HPLC)
- Packaging
- 25G
- Price
- $430
- Updated
- 2021/12/16
- Product number
- AAA0001643
- Product name
- N-FMOC-L-ALANINOL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $751
- Updated
- 2021/12/16
- Product number
- AAA0001643
- Product name
- N-FMOC-L-ALANINOL
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1079.35
- Updated
- 2021/12/16
FMOC-L-ALANINOL Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Synthesis
35661-39-3
161529-13-1
GENERAL METHODS: To a tetrahydrofuran (THF, 10 mL) solution of N-fluorenylmethoxycarbonyl-L-alanine (10 mmol) was added a solution of N,N-diisopropylethylamine (DIPEA, 11 mmol, 1.42 mL) and a solution of ethyl acetate (EtOAc) (20 mmol, 6.36 mL) of 50% propylphosphonic anhydride (T3P) at 0 °C and stirred for about 10 min. Then sodium borohydride (NaBH4) aqueous solution (10 mmol, 388 mg, dissolved in 0.3 mL of water) was slowly added to the reaction mixture at the same temperature, and the progress of the reaction was monitored by thin layer chromatography (TLC) until the reaction was completed. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure, and the crude product was extracted with ethyl acetate (EtOAc), and the organic phase was washed sequentially with 5% aqueous citric acid (10 mL x 2), 5% aqueous sodium carbonate (Na2CO3) (10 mL x 2), water and saturated saline. The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and the solvent was evaporated under reduced pressure to obtain the target product, N-fluorenylmethoxycarbonyl-L-alaninol.
References
[1] Journal of Organic Chemistry, 2001, vol. 66, # 25, p. 8454 - 8462
[2] Tetrahedron Letters, 2000, vol. 41, # 32, p. 6131 - 6135
[3] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[4] Journal of Molecular Liquids, 2014, vol. 198, p. 94 - 100
[5] RSC Advances, 2014, vol. 4, # 87, p. 46947 - 46950
FMOC-L-ALANINOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from FMOC-L-ALANINOL manufacturers
- Product
- Fmoc-L-Ala-Ol 161529-13-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98+
- Supply Ability
- 1T+
- Release date
- 2024-01-15
- Product
- FMOC-L-ALANINOL 161529-13-1
- Price
- US $1.00/g
- Min. Order
- 100g
- Purity
- >98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-01-14
- Product
- Fmoc-Ala-Ol 161529-13-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2019-07-23