ChemicalBook > CAS DataBase List > Fmoc-Pro-OH

Fmoc-Pro-OH

Product Name
Fmoc-Pro-OH
CAS No.
71989-31-6
Chemical Name
Fmoc-Pro-OH
Synonyms
FMOC-PRO-OH;FMOC-PRO;FMOC-L-;FMOC-L-PRO-OH;FMOC-L-PRO;FMOC-PRO-OH H2O;FMOC-PROLINE;L-PROLINE-N-FMOC;FMOC-L-PRO-OH H2O;N-(9-FLUORENYLMETHOXYCARBONYL)-L-PYRROLIDINE-2-CARBOXYLIC ACID
CBNumber
CB8189794
Molecular Formula
C20H19NO4
Formula Weight
337.37
MOL File
71989-31-6.mol
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Fmoc-Pro-OH Property

Melting point:
117-118 °C(lit.)
alpha 
-32 º (c=1,DMF)
Boiling point:
473.68°C (rough estimate)
Density 
1.2486 (rough estimate)
refractive index 
-32.5 ° (C=1, DMF)
storage temp. 
Store below +30°C.
solubility 
Soluble in methanol. (almost transparency.)
form 
Solid
pka
3.95±0.20(Predicted)
color 
White to Off-White
optical activity
[α]20/D 32±1°, c = 1% in DMF
BRN 
3596735
Concentration
0.1 mCi/ml
Solvent
Ethanol
Specific Activity
50-60 mCi/mmol
CAS DataBase Reference
71989-31-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
HS Code 
2933 99 80
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
25g
Price
$36.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
100g
Price
$70
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
250g
Price
$162
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
1kg
Price
$554
Updated
2024/03/01
Sigma-Aldrich
Product number
47636
Product name
Fmoc-Pro-OH
Purity
≥99.0% (HPLC)
Packaging
5G
Price
$36.4
Updated
2024/03/01
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Fmoc-Pro-OH Chemical Properties,Usage,Production

Description

Fmoc-Pro-OH is easily dissolved in DMF or NMP. Proline fails to produce a blue-to purple color in the Kaiser test. The Isatin test may be used to test the completion of couplings to proline residues.

Chemical Properties

white to light yellow crystal powder.

Uses

L-Proline-N-Fmoc is N-Fmoc protected L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.

Preparation

To a solution of (S)-pyrrolidine-2-carboxylic acid (1 g, 8.7 mmol) in 1,4-dioxane (4 mL) and water (15 mL), K2CO3 (3.24 g, 23 mmol) was added, followed by the addition of 9-fluorenylmethyl chloroformate (2.3 g, 8.3 mmol). The resulting mixture was stirred overnight at room temperature and then treated with water (10 mL). The resulting mixture was extracted with diethyl ether (2 x 20 mL), and the aqueous phase was made acidic with 1M HCl to a pH of 2-3, followed by extraction with dichloromethane (3 x 50 mL). The combined organic layers were dried using anhydrous sodium sulfate and concentrated to yield Fmoc-Pro-OH as a white solid in a 95% yield (2.8 g).

General Description

The product number for this product was previously 04-12-1031.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Fmoc-Pro-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Pro-OH Suppliers

Americas 1 Belgium 1 Canada 2 China 387 Europe 5 France 2 Germany 7 Hungary 1 India 40 Israel 2 Italy 2 Japan 8 Poland 1 Switzerland 7 United Kingdom 18 United States 76 Global 560
Wuhan Grand Hoyo Co., Ltd.
Tel
15377006636
Email
670196467@qq.com
Country
China
ProdList
30
Advantage
58
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
GenChem & GenPharm (Changzhou) Co., Ltd.
Tel
0519-85720003 18861157602
Fax
0519-85720007
Email
sales03@genchem.cn
Country
China
ProdList
111
Advantage
58
Chengdu Tachem Co., Ltd
Tel
028-61682518; 19983060238
Email
sales@tachem.cn
Country
China
ProdList
103
Advantage
58
Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019
Email
boyu2024@163.com
Country
China
ProdList
2735
Advantage
58
Zepeptide Biotechnology (Shijiazhuang) Co., LTD
Tel
13383293380 18032131480
Email
649498984@qq.com
Country
China
ProdList
75
Advantage
58
Nanjing Yihua Biotechnology Co., Ltd
Tel
15952064210
Email
184982398@qq.com
Country
China
ProdList
280
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
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View Lastest Price from Fmoc-Pro-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Pro-OH 71989-31-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-13
WUHAN FORTUNA CHEMICAL CO., LTD
Product
FMOC-L-Proline 71989-31-6
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-08-28
Henan Fengda Chemical Co., Ltd
Product
Fmoc-Pro-OH 71989-31-6
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-02

71989-31-6, Fmoc-Pro-OHRelated Search:

L-Proline Fmoc-Aib-OH Fmoc-Asp(OtBu)-OH Fmoc-Lys(Boc)-OH L-PROLINE-(4-3H(N)) L-Fmoc-Aspartic acid alpha-tert-butyl ester cis-4-Hydroxy-L-proline N-(9-Fluorenylmethoxycarbonyloxy)succinimide D-Proline Fmoc-Phe-OH 9-Fluorenylmethyl chloroformate 9-Fluorenemethanol FMOC-L-Methionine FMOC-S-trityl-L-cysteine Fmoc-Trp(Boc)-OH Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Tyr(tBu)-OH Nalpha-FMOC-L-Tryptophan

  • N-9-FLUORENYLMETHYLOXYCARBONYL-L-PROLINE
  • N-(9-FLUOROENYLMETHOXYCARBONYL)-L-SERINE
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-PYRROLIDINE-2-CARBOXYLIC ACID
  • N-ALPHA-FMOC-L-PROLINE
  • 9-FLUORENYLMETHOXYCARBONYL-L-PROLINE
  • FMOC-L-PRO-OH
  • FMOC-L-PRO-OH H2O
  • FMOC-L-PROLINE
  • FMOC-L-PRO
  • FMOC-PROLINE
  • FMOC-PRO-OH
  • FMOC-PRO-OH H2O
  • FMOC-PYRD(2)-OH
  • FMOC-PRO
  • 1-(9H-fluoren-9-ylmethyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
  • FMOC-L-PROLINE 99+%
  • N-FMOC-PRO-OH ( N-FMOC-L-PROLINE)
  • L-Proline-UL-13C5, 15N-N-FMOC
  • L-PROLINE-N-FMOC
  • Fmoc-L-proline Fmoc-Pro-OH
  • (S)-1-(((9H-fluoren-9-yl)Methoxy)carbonyl)pyrrolidine-2-carboxylic acid
  • FMoc-Pro-OH >=99.0% (HPLC)
  • MOC-L-Proline
  • (S)-Fmoc-pyrrolidine-2-carboxylic acid
  • Fmoc-L-proline≥ 99.7% (HPLC, Chiral purity)
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Pro-OH
  • FMOC-L-
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE(FMOC-L-PRO-OH)
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-PROLINE MONOHYDRATE
  • N-FMOC-L-PRO
  • N-FMOC-L-PROLINE
  • N-FMOC-PRO-OH
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE MONOHYDRATE
  • N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-PROLINE
  • 1-(9H-fFuoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
  • N-(9-Fluorenylmethoxycarbonyl)-L-proline ,98%
  • FMOC-L-PROLINE extrapure
  • N-(9-Fluorenylmethoxycarbonyl)-L-proline, Fmoc-L-proline
  • (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester
  • 1-(9H-Fluorene-9-ylmethoxycarbonyl)proline
  • 1-[(9H-Fluorene-9-yl)methoxycarbonyl]-L-proline
  • 1-[(9H-Fluorene-9-ylmethoxy)carbonyl]-L-proline
  • N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-proline
  • N-alpha-(9-fluorenylmethyloxycarbonyl)-L-proline
  • Fmoc-L-prolone
  • Fmoc-L-proline ,98%
  • Fmoc-Proline-OH
  • (2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
  • FMOC-L-PRO-OH(71989-31-6)
  • FMOC-Pro-OH 98%
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-proline&gt
  • FMOC-PRO-OH 250 G
  • FMOC-PRO-OH 100 G
  • 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (2S)-
  • (2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylicaci
  • FMOC-L-Proline USP/EP/BP