ChemicalBook > CAS DataBase List > Fmoc-Pro-OH

Fmoc-Pro-OH

Product Name
Fmoc-Pro-OH
CAS No.
71989-31-6
Chemical Name
Fmoc-Pro-OH
Synonyms
FMOC-PRO-OH;FMOC-PRO;FMOC-L-;FMOC-L-PRO-OH;FMOC-L-PRO;FMOC-PRO-OH H2O;FMOC-PROLINE;L-PROLINE-N-FMOC;FMOC-L-PRO-OH H2O;N-(9-FLUORENYLMETHOXYCARBONYL)-L-PYRROLIDINE-2-CARBOXYLIC ACID
CBNumber
CB8189794
Molecular Formula
C20H19NO4
Formula Weight
337.37
MOL File
71989-31-6.mol
More
Less

Fmoc-Pro-OH Property

Melting point:
117-118 °C(lit.)
alpha 
-32 º (c=1,DMF)
Boiling point:
473.68°C (rough estimate)
Density 
1.2486 (rough estimate)
refractive index 
-32.5 ° (C=1, DMF)
storage temp. 
Store below +30°C.
solubility 
Soluble in methanol. (almost transparency.)
form 
Solid
pka
3.95±0.20(Predicted)
color 
White to Off-White
optical activity
[α]20/D 32±1°, c = 1% in DMF
BRN 
3596735
Concentration
0.1 mCi/ml
Solvent
Ethanol
Specific Activity
50-60 mCi/mmol
CAS DataBase Reference
71989-31-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
HS Code 
2933 99 80
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
25g
Price
$36.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
100g
Price
$70
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
250g
Price
$162
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52017
Product name
Fmoc-Pro-OH
Purity
Novabiochem?
Packaging
1kg
Price
$554
Updated
2024/03/01
Sigma-Aldrich
Product number
47636
Product name
Fmoc-Pro-OH
Purity
≥99.0% (HPLC)
Packaging
5G
Price
$36.4
Updated
2024/03/01
More
Less

Fmoc-Pro-OH Chemical Properties,Usage,Production

Description

Fmoc-Pro-OH is easily dissolved in DMF or NMP. Proline fails to produce a blue-to purple color in the Kaiser test. The Isatin test may be used to test the completion of couplings to proline residues.

Chemical Properties

white to light yellow crystal powder.

Uses

L-Proline-N-Fmoc is N-Fmoc protected L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.

Preparation

To a solution of (S)-pyrrolidine-2-carboxylic acid (1 g, 8.7 mmol) in 1,4-dioxane (4 mL) and water (15 mL), K2CO3 (3.24 g, 23 mmol) was added, followed by the addition of 9-fluorenylmethyl chloroformate (2.3 g, 8.3 mmol). The resulting mixture was stirred overnight at room temperature and then treated with water (10 mL). The resulting mixture was extracted with diethyl ether (2 x 20 mL), and the aqueous phase was made acidic with 1M HCl to a pH of 2-3, followed by extraction with dichloromethane (3 x 50 mL). The combined organic layers were dried using anhydrous sodium sulfate and concentrated to yield Fmoc-Pro-OH as a white solid in a 95% yield (2.8 g).

General Description

The product number for this product was previously 04-12-1031.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Fmoc-Pro-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Fmoc-Pro-OH Suppliers

Americas 1 Belgium 1 Canada 2 China 389 Europe 5 France 2 Germany 7 Hungary 1 India 41 Israel 2 Italy 2 Japan 8 Poland 1 Switzerland 7 United Kingdom 18 United States 76 Global 563
Wuhan Grand Hoyo Co., Ltd.
Tel
15377006636
Email
670196467@qq.com
Country
China
ProdList
30
Advantage
58
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
GenChem & GenPharm (Changzhou) Co., Ltd.
Tel
0519-85720003 18861157602
Fax
0519-85720007
Email
sales03@genchem.cn
Country
China
ProdList
111
Advantage
58
Chengdu Tachem Co., Ltd
Tel
028-61682518; 19983060238
Email
sales@tachem.cn
Country
China
ProdList
103
Advantage
58
Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019
Email
boyu2024@163.com
Country
China
ProdList
2730
Advantage
58
Zepeptide Biotechnology (Shijiazhuang) Co., LTD
Tel
13383293380 18032131480
Email
649498984@qq.com
Country
China
ProdList
75
Advantage
58
Nanjing Yihua Biotechnology Co., Ltd
Tel
13429882898
Email
1096323105@qq.com
Country
China
ProdList
280
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Sichuan Tongsheng Amino acids Co.,Ltd.
Tel
0838-2809458 13350585791
Fax
+86-838-2274207
Email
pharm@biots.cn
Country
China
ProdList
333
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9511
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8835
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Suzhou Guide Fine Material Co.Ltd.
Tel
136-16210669 13914021065
Fax
0512-66627360
Email
sales@guide-chemicals.com
Country
China
ProdList
271
Advantage
60
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Emeishan Hongsen Biopharmaceutical Co., Ltd.
Tel
0833-6186278 19162541913;
Fax
0833-5590359
Email
sales@hongshengpharm.com
Country
China
ProdList
109
Advantage
60
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9894
Advantage
55
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Nanjing Redwood Fine Chemical Co., Ltd.
Tel
13851620508 13851620508
Fax
86-025-58905816
Email
shirly@redwood.com.cn
Country
China
ProdList
218
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
More
Less

View Lastest Price from Fmoc-Pro-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Pro-OH 71989-31-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-13
WUHAN FORTUNA CHEMICAL CO., LTD
Product
FMOC-L-Proline 71989-31-6
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-08-28
Henan Fengda Chemical Co., Ltd
Product
Fmoc-Pro-OH 71989-31-6
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-02

71989-31-6, Fmoc-Pro-OHRelated Search:

L-Proline Fmoc-Aib-OH Fmoc-Asp(OtBu)-OH Fmoc-Lys(Boc)-OH L-PROLINE-(4-3H(N)) L-Fmoc-Aspartic acid alpha-tert-butyl ester cis-4-Hydroxy-L-proline N-(9-Fluorenylmethoxycarbonyloxy)succinimide D-Proline Fmoc-Phe-OH 9-Fluorenylmethyl chloroformate 9-Fluorenemethanol FMOC-L-Methionine FMOC-S-trityl-L-cysteine Fmoc-Trp(Boc)-OH Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Tyr(tBu)-OH Nalpha-FMOC-L-Tryptophan

  • N-9-FLUORENYLMETHYLOXYCARBONYL-L-PROLINE
  • N-(9-FLUOROENYLMETHOXYCARBONYL)-L-SERINE
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-PYRROLIDINE-2-CARBOXYLIC ACID
  • N-ALPHA-FMOC-L-PROLINE
  • 9-FLUORENYLMETHOXYCARBONYL-L-PROLINE
  • FMOC-L-PRO-OH
  • FMOC-L-PRO-OH H2O
  • FMOC-L-PROLINE
  • FMOC-L-PRO
  • FMOC-PROLINE
  • FMOC-PRO-OH
  • FMOC-PRO-OH H2O
  • FMOC-PYRD(2)-OH
  • FMOC-PRO
  • 1-(9H-fluoren-9-ylmethyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
  • FMOC-L-PROLINE 99+%
  • N-FMOC-PRO-OH ( N-FMOC-L-PROLINE)
  • L-Proline-UL-13C5, 15N-N-FMOC
  • L-PROLINE-N-FMOC
  • Fmoc-L-proline Fmoc-Pro-OH
  • (S)-1-(((9H-fluoren-9-yl)Methoxy)carbonyl)pyrrolidine-2-carboxylic acid
  • FMoc-Pro-OH >=99.0% (HPLC)
  • MOC-L-Proline
  • (S)-Fmoc-pyrrolidine-2-carboxylic acid
  • Fmoc-L-proline≥ 99.7% (HPLC, Chiral purity)
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Pro-OH
  • FMOC-L-
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE(FMOC-L-PRO-OH)
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-PROLINE MONOHYDRATE
  • N-FMOC-L-PRO
  • N-FMOC-L-PROLINE
  • N-FMOC-PRO-OH
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-PROLINE MONOHYDRATE
  • N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-PROLINE
  • 1-(9H-fFuoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
  • N-(9-Fluorenylmethoxycarbonyl)-L-proline ,98%
  • FMOC-L-PROLINE extrapure
  • N-(9-Fluorenylmethoxycarbonyl)-L-proline, Fmoc-L-proline
  • (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester
  • 1-(9H-Fluorene-9-ylmethoxycarbonyl)proline
  • 1-[(9H-Fluorene-9-yl)methoxycarbonyl]-L-proline
  • 1-[(9H-Fluorene-9-ylmethoxy)carbonyl]-L-proline
  • N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-proline
  • N-alpha-(9-fluorenylmethyloxycarbonyl)-L-proline
  • Fmoc-L-prolone
  • Fmoc-L-proline ,98%
  • Fmoc-Proline-OH
  • (2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
  • FMOC-L-PRO-OH(71989-31-6)
  • FMOC-Pro-OH 98%
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-proline&gt
  • FMOC-PRO-OH 250 G
  • FMOC-PRO-OH 100 G
  • 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (2S)-
  • (2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylicaci
  • FMOC-L-Proline USP/EP/BP