Fmoc-Pro-OH
- Product Name
- Fmoc-Pro-OH
- CAS No.
- 71989-31-6
- Chemical Name
- Fmoc-Pro-OH
- Synonyms
- FMOC-PRO-OH;FMOC-PRO;FMOC-L-;FMOC-L-PRO-OH;FMOC-L-PRO;FMOC-PRO-OH H2O;FMOC-PROLINE;L-PROLINE-N-FMOC;FMOC-L-PRO-OH H2O;N-(9-FLUORENYLMETHOXYCARBONYL)-L-PYRROLIDINE-2-CARBOXYLIC ACID
- CBNumber
- CB8189794
- Molecular Formula
- C20H19NO4
- Formula Weight
- 337.37
- MOL File
- 71989-31-6.mol
Fmoc-Pro-OH Property
- Melting point:
- 117-118 °C(lit.)
- alpha
- -32 º (c=1,DMF)
- Boiling point:
- 473.68°C (rough estimate)
- Density
- 1.2486 (rough estimate)
- refractive index
- -32.5 ° (C=1, DMF)
- storage temp.
- Store below +30°C.
- solubility
- Soluble in methanol. (almost transparency.)
- form
- Solid
- pka
- 3.95±0.20(Predicted)
- color
- White to Off-White
- optical activity
- [α]20/D 32±1°, c = 1% in DMF
- BRN
- 3596735
- Concentration
- 0.1 mCi/ml
- Solvent
- Ethanol
- Specific Activity
- 50-60 mCi/mmol
- CAS DataBase Reference
- 71989-31-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- HS Code
- 2933 99 80
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.52017
- Product name
- Fmoc-Pro-OH
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $36.5
- Updated
- 2024/03/01
- Product number
- 8.52017
- Product name
- Fmoc-Pro-OH
- Purity
- Novabiochem?
- Packaging
- 100g
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 8.52017
- Product name
- Fmoc-Pro-OH
- Purity
- Novabiochem?
- Packaging
- 250g
- Price
- $162
- Updated
- 2024/03/01
- Product number
- 8.52017
- Product name
- Fmoc-Pro-OH
- Purity
- Novabiochem?
- Packaging
- 1kg
- Price
- $554
- Updated
- 2024/03/01
- Product number
- 47636
- Product name
- Fmoc-Pro-OH
- Purity
- ≥99.0% (HPLC)
- Packaging
- 5G
- Price
- $36.4
- Updated
- 2024/03/01
Fmoc-Pro-OH Chemical Properties,Usage,Production
Description
Fmoc-Pro-OH is easily dissolved in DMF or NMP. Proline fails to produce a blue-to purple color in the Kaiser test. The Isatin test may be used to test the completion of couplings to proline residues.
Chemical Properties
white to light yellow crystal powder.
Uses
L-Proline-N-Fmoc is N-Fmoc protected L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.
Preparation
To a solution of (S)-pyrrolidine-2-carboxylic acid (1 g, 8.7 mmol) in 1,4-dioxane (4 mL) and water (15 mL), K2CO3 (3.24 g, 23 mmol) was added, followed by the addition of 9-fluorenylmethyl chloroformate (2.3 g, 8.3 mmol). The resulting mixture was stirred overnight at room temperature and then treated with water (10 mL). The resulting mixture was extracted with diethyl ether (2 x 20 mL), and the aqueous phase was made acidic with 1M HCl to a pH of 2-3, followed by extraction with dichloromethane (3 x 50 mL). The combined organic layers were dried using anhydrous sodium sulfate and concentrated to yield Fmoc-Pro-OH as a white solid in a 95% yield (2.8 g).
General Description
The product number for this product was previously 04-12-1031.
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Fmoc-Pro-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-Pro-OH Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from Fmoc-Pro-OH manufacturers
- Product
- Fmoc-L-Pro-OH 71989-31-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-12-13
- Product
- FMOC-L-Proline 71989-31-6
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg
- Release date
- 2021-08-28
- Product
- Fmoc-Pro-OH 71989-31-6
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-02