Uses
ChemicalBook > CAS DataBase List > 2,4-DICHLORO-3-NITRO-QUINOLINE

2,4-DICHLORO-3-NITRO-QUINOLINE

Uses
Product Name
2,4-DICHLORO-3-NITRO-QUINOLINE
CAS No.
132521-66-5
Chemical Name
2,4-DICHLORO-3-NITRO-QUINOLINE
Synonyms
Zinc02551827;AURORA KA-4144;2,4-Dichlor-3-nitro-chinolin;3-NITRO-2,4-DICHLORO QUINOLINE;2,4-DICHLORO-3-NITRO-QUINOLINE;Quinoline, 2,4-dichloro-3-nitro-;2,4-Dichloro-3-nitroquinoline 95%;Benzaldehyde,4-methoxy-4-(phenylmethoxy)-;2,4-DICHLORO-3-NITRO-QUINOLINE ISO 9001：2015 REACH
CBNumber
CB5773772
Molecular Formula
C9H4Cl2N2O2
Formula Weight
243.05
MOL File
132521-66-5.mol
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2,4-DICHLORO-3-NITRO-QUINOLINE Property

Melting point:
102 °C(Solv: methanol (67-56-1); ethyl acetate (141-78-6))
Boiling point:
359.7±37.0 °C(Predicted)
Density 
1.593±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
-4.98±0.50(Predicted)
color 
White to Off-White
InChI
InChI=1S/C9H4Cl2N2O2/c10-7-5-3-1-2-4-6(5)12-9(11)8(7)13(14)15/h1-4H
InChIKey
RSFJVCHKGRUCIC-UHFFFAOYSA-N
SMILES
N1C2C(=CC=CC=2)C(Cl)=C([N+]([O-])=O)C=1Cl
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Safety

HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D439308
Product name
2,4-Dichloro-3-nitroquinoline
Packaging
50mg
Price
$125
Updated
2021/12/16
SynQuest Laboratories
Product number
4H54-5-2U
Product name
2,4-Dichloro-3-nitroquinoline
Packaging
250mg
Price
$376
Updated
2021/12/16
SynQuest Laboratories
Product number
4H54-5-2U
Product name
2,4-Dichloro-3-nitroquinoline
Packaging
1g
Price
$824
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0142593
Product name
2,4-DICHLORO-3-NITRO-QUINOLINE
Purity
97.00%
Packaging
1G
Price
$1022.18
Updated
2021/12/16
Matrix Scientific
Product number
128520
Product name
2,4-Dichloro-3-nitroquinoline
Purity
97%
Packaging
1g
Price
$495
Updated
2021/12/16
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2,4-DICHLORO-3-NITRO-QUINOLINE Chemical Properties,Usage,Production

Uses

2,4-Dichloro-3-nitroquinoline has antitumor activity.

Uses

2,4-Dichloro-3-nitroquinoline has antitumor activity.

Synthesis

15151-57-2

132521-66-5

(2) Synthesis of 2,4-dichloro-3-nitroquinoline: In a 20 mL round-bottomed flask, 3-nitroquinoline-2,4-diol (1 g, 4.85 mmol), phosphorus trichloride (appropriate amount) and N,N-dimethylaniline (0.19 mL) were added sequentially. The reaction mixture was stirred at 90 °C for 2 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature, slowly poured into ice water, and stirring was continued for 0.5 hours. The precipitate precipitated was collected by filtration and dried under vacuum overnight. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=5:1, v/v) to give 0.7 g of white solid product in 59.4% yield.

References

[1] Medicinal Chemistry Research, 2014, vol. 23, # 6, p. 2964 - 2975
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 11, p. 4450 - 4465
[3] Patent: WO2013/67597, 2013, A1. Location in patent: Page/Page column 78
[4] Patent: WO2018/191746, 2018, A1. Location in patent: Paragraph 0391
[5] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 8, p. 921 - 926

2,4-DICHLORO-3-NITRO-QUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DICHLORO-3-NITRO-QUINOLINE Suppliers

Austria 1 China 76 Germany 2 India 6 United Kingdom 2 United States 13 Global 100
Aurora Fine Chemicals Ltd.
Tel
--
Fax
--
Email
aurora@aurorafinechemicals.com
Country
Austria
ProdList
6625
Advantage
72
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View Lastest Price from 2,4-DICHLORO-3-NITRO-QUINOLINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2,4-DICHLORO-3-NITRO-QUINOLINE 132521-66-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-06-21
Career Henan Chemical Co
Product
2,4-DICHLORO-3-NITRO-QUINOLINE 132521-66-5
Price
US $1.00/KG
Min. Order
1KG
Purity
97%
Supply Ability
200KG
Release date
2018-08-15

132521-66-5, 2,4-DICHLORO-3-NITRO-QUINOLINERelated Search:

2,4-DIBROMO-3-CHLOROPYRIDINE 7-Benzyl-2,4-dichloro-5,6... 2,4-Dibromothiazole-5-methanol 2,4-DIBROMO-5-NITROPYRIDINE 2,4-dichloro-6-phenylpyrimidine 2,4-dichloro-5-iodo-6-methylpyrimidine CHEMPACIFIC 38112 2,4-DIBROMOBENZOTHIAZOLE 5-Thiazolecarboxylic acid, 2,4-dibromo- 4-Chloro-3-nitropyridine hydrochloride 4-Chloro-3-nitropyridine 3-Amino-4-chloropyridine 4-Chloro-3-nitroquinoline 2,4-Dichloro-3-nitropyridine Ethyl 5-Bromoindole-2-carboxylate 2,4-DICHLORO-3-NITRO-QUINOLINE 2,4-DICHLORO-3-AMINOPYRIDINE 2-CHLORO-3-NITROQUINOLINE

  • AURORA KA-4144
  • 2,4-DICHLORO-3-NITRO-QUINOLINE
  • 3-NITRO-2,4-DICHLORO QUINOLINE
  • 2,4-Dichlor-3-nitro-chinolin
  • Zinc02551827
  • 2,4-Dichloro-3-nitroquinoline 95%
  • Quinoline, 2,4-dichloro-3-nitro-
  • 2,4-DICHLORO-3-NITRO-QUINOLINE ISO 9001：2015 REACH
  • Benzaldehyde,4-methoxy-4-(phenylmethoxy)-
  • 132521-66-5