canadine
- Product Name
- canadine
- CAS No.
- 5096-57-1
- Chemical Name
- canadine
- Synonyms
- C03329;(-)-Canadine;(S)-Canadine;(S)-Tetrahydroberberine;(13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-
- CBNumber
- CB5939134
- Molecular Formula
- C20H21NO4
- Formula Weight
- 339.39
- MOL File
- 5096-57-1.mol
canadine Property
- Melting point:
- 135°
- alpha
- D22 -308°; -317° (c = 0.28; 0.4, both in methanol)
- Boiling point:
- 475.36°C (rough estimate)
- Density
- 1.2270 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Refrigerator
- solubility
- Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
- form
- Solid
- pka
- 6.53±0.20(Predicted)
- color
- Pale Yellow to Light Yellow
Safety
- RIDADR
- 1544
- HazardClass
- 6.1(b)
- PackingGroup
- III
N-Bromosuccinimide Price
- Product number
- C175180
- Product name
- (S)-(-)-Canadine
- Packaging
- 250mg
- Price
- $1455
- Updated
- 2021/12/16
- Product number
- 55371
- Product name
- (S)-(-)-Canadine
- Packaging
- 250mg
- Price
- $2200
- Updated
- 2021/12/16
- Product number
- PXT0002233
- Product name
- L-CANADINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.05
- Updated
- 2021/12/16
- Product number
- CD32001189
- Product name
- Canadine
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $640
- Updated
- 2021/12/16
- Product number
- CFN98810
- Product name
- Canadine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $463
- Updated
- 2021/12/16
canadine Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
(S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as n ew antipsychotic agents.
Uses
(S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
Definition
ChEBI: (S)-canadine is the (S)-enantiomer of canadine. It has a role as a plant metabolite. It is functionally related to a (S)-nandinine. It is an enantiomer of a (R)-canadine.
target
P450 (e.g. CYP17)
canadine Preparation Products And Raw materials
Raw materials
Preparation Products
canadine Suppliers
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View Lastest Price from canadine manufacturers
- Product
- Canadine 5096-57-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-16