ChemicalBook > CAS DataBase List > 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID

3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID

Product Name
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
CAS No.
67-30-1
Chemical Name
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
Synonyms
TETRAC;tetraiodothyroaceticacid;Liothyronine EP Impurity D;Levothyroxine – Impurity D;Levothyroxine EP Impurity D;Liothyronine Sodium Impurity D;3,5,3’,5’-tetraiodothyroacetique;Liothyronine Sodium EP Impurity D;3,3’,5,5’-tetraiodo-thyroaceticaci;Levothyroxine Sodium EP Impurity D
CBNumber
CB6124010
Molecular Formula
C14H8I4O4
Formula Weight
747.83
MOL File
67-30-1.mol
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3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Property

Melting point:
219-220 °C (decomp)
Boiling point:
544.8±50.0 °C(Predicted)
Density 
2.727±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
acetone: soluble19.60 - 20.40mg/mL, clear, colorless (or faintly yellow to yellow)
form 
powder to crystal
pka
3.98±0.10(Predicted)
color 
White to Yellow to Green
InChIKey
PPJYSSNKSXAVDB-UHFFFAOYSA-N
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Safety

Hazard Codes 
T+
Risk Statements 
28
Safety Statements 
45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
CY1585800
HS Code 
2916.39.7900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3787
Product name
3,3′,5,5′-Tetraiodothyroacetic acid
Packaging
25mg
Price
$138
Updated
2024/03/01
Sigma-Aldrich
Product number
T3787
Product name
3,3′,5,5′-Tetraiodothyroacetic acid
Packaging
100mg
Price
$409
Updated
2024/03/01
TCI Chemical
Product number
T3730
Product name
3,3',5,5'-Tetraiodothyroacetic Acid
Packaging
100MG
Price
$229
Updated
2024/03/01
TCI Chemical
Product number
T3730
Product name
3,3',5,5'-Tetraiodothyroacetic Acid
Packaging
500MG
Price
$695
Updated
2024/03/01
TRC
Product number
T296125
Product name
3,5,3'',5''-TetraiodoThyroaceticAcid
Packaging
50mg
Price
$100
Updated
2021/12/16
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3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Chemical Properties,Usage,Production

Uses

Thyroid hormone analogue

Uses

3,3′,5,5′-Tetraiodothyroacetic acid has been used:

  • as a positive control to study the effects of ioxynil (IOX)
  • diethylstilbestrol (DES) exposure on zebrafish embryos
  • to study its effects on long-term potentiation (LTP) and long-term depression (LTD) in the dentate gyrus in urethane-anesthetized male rats
  • to determine its influence on the actions of thyroid-stimulating hormone
  • thyroid-stimulating immunoglobulins in orbital fibroblast

Definition

ChEBI: A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'.

Biochem/physiol Actions

Studies in rats have reported that Tetrac may regulate TSH secretion under in vivo conditions1.

3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Suppliers

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View Lastest Price from 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID manufacturers

Career Henan Chemical Co
Product
2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid 67-30-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-09

67-30-1, 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACIDRelated Search:

3,3',5-TRIIODOTHYROACETIC ACID 3,5-Diiodo-L-thyronine 3,3',5-TRIIODOTHYROPROPIONIC ACID Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED 3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID REVERSE T3 N-ForMyl Thyroxine 3,5,3',5'-Tetraiodo Thyroaldehyde 3-IODO-L-TYROSINE 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetaMide 3,3',5-Triiodo-L-thyronine 3,5,3',5'-Tetraiodo Thyrolactic Acid 2',6'-Pipecoloxylidide 2-Piperidone 3,5-Diiodo-L-tyrosine dihydrate 3,4-Dimethoxy-L-phenylalanine Levothyroxine EP Impurity B Sodium levothyroxine

  • 3,3’,5,5’-tetraiodo-thyroaceticaci
  • 3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)-benzeneaceticaci
  • 3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneaceticacid
  • acide3,5,3’,5’-tetraiodothyroacetique
  • Levothyroxine – Impurity D
  • Liothyronine EP Impurity D
  • tetraiodothyroaceticacid
  • 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylacetic acid
  • 3,5-DIIODO-4-(4-HYDROXY-3,5-DIIODOPHENOXY)PHENYLACETIC ACID
  • 4-[4-HYDROXY-3,5-DIIODOPHENOXY]-3,5-DIIODOBENZENEACETIC ACID
  • 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
  • [3,5-Diiodo-4-(3,5-diiodo-4-hydroxyphenoxy)phenyl]acetic acid
  • 2-[3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)phenyl]acetic acid
  • 3,5,3',5'-Tetraiodothyroacetic acid
  • 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetic acid, Tetrac
  • Benzeneacetic acid,4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-
  • Levothyroxine EP Impurity D
  • TETRAC
  • (4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-aceticaci
  • Levothyroxine Impurity 4（Levothyroxine EP Impurity D）
  • Levothyroxine impurity 14/Liothyronine EP Impurity D/2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid
  • Levothyroxine EP Impurity D/ T4-Acetic Acid (Liothyronine EP Impurity D/ Tetraiodothyroacetic Acid)
  • Liothyronine EP Impurity D (Tetraiodothyroacetic Acid/ Levothyroxine EP Impurity D/ T4-Acetic Acid)
  • 3,5,3’,5’-tetraiodothyroacetique
  • Liothyronine Sodium Impurity D
  • Levothyroxine Sodium EP Impurity D
  • Liothyronine Sodium EP Impurity D
  • Levothyroxine EP Impurity-D (T4 acetic acid)
  • 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
  • 3，5，3’，5’-Tetraiodo Thyroacetic Acid
  • 67-30-1
  • C14H8I4O4
  • C14H8O4I4
  • Aromatic Phenylacetic Acids and Derivatives
  • Aromatics
  • Drug Analogues
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals