3-BROMO-5-NITROBENZALDEHYDE

Product Name: 3-BROMO-5-NITROBENZALDEHYDE
CAS No.: 355134-13-3
Chemical Name: 3-BROMO-5-NITROBENZALDEHYDE
Synonyms: 3-BROMO-5-NITROBENZALDEHYDE;3-Nitro-5-bromo-benzaldehyde;3-Bromo-5-formylnitrobenzene;3-Fluoro-5-nitrobenzaldehyde;Benzaldehyde,3-bromo-5-nitro-;3-Bromo-5-nitrobenzaldehyde 95%;3-BroMo-5-nitrobenzaldehyde, 97+%
CBNumber: CB61471016
Molecular Formula: C7H4BrNO3
Formula Weight: 230.02
MOL File: 355134-13-3.mol

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3-BROMO-5-NITROBENZALDEHYDE Property

Melting point:: 101-106 °C
Boiling point:: 306.9±27.0 °C(Predicted)
Density: 1.781
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in Methanol
form: Powder
color: Pale brown

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38-43
Safety Statements: 26-36/37
WGK Germany: 3
HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 702986
Product name: 3-Bromo-5-nitrobenzaldehyde
Purity: 97%
Packaging: 250mg
Price: $69.5
Updated: 2023/01/07

Sigma-Aldrich

Product number: 702986
Product name: 3-Bromo-5-nitrobenzaldehyde
Purity: 97%
Packaging: 1g
Price: $125
Updated: 2023/01/07

TCI Chemical

Product number: B4982
Product name: 3-Bromo-5-nitrobenzaldehyde
Packaging: 1G
Price: $73
Updated: 2025/07/31

TCI Chemical

Product number: B4982
Product name: 3-Bromo-5-nitrobenzaldehyde
Packaging: 5G
Price: $219
Updated: 2025/07/31

TRC

Product number: B699445
Product name: 3-Bromo-5-nitrobenzaldehyde
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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3-BROMO-5-NITROBENZALDEHYDE Chemical Properties,Usage,Production

Uses

3-Fluoro-5-nitrobenzaldehyde is used as a reactant in the design and synthesis of selective activators of cardiac myosin.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 5867, 2007 DOI: 10.1021/jo070477u

Synthesis

99-61-6

355134-13-3

General procedure for the synthesis of 3-bromo-5-nitrobenzaldehyde from m-nitrobenzaldehyde: 3-nitrobenzaldehyde (1.0 g, 6.6 mmol) was dissolved in concentrated sulfuric acid (4.0 mL) at room temperature, followed by batchwise addition of N-bromosuccinimide (1.4 g, 7.9 mmol). The reaction mixture was heated to 65 °C and maintained at this temperature for 1 hour. After completion of the reaction, it was cooled to room temperature and the reaction solution was slowly poured into ice water, the solid was precipitated and collected by filtration. The crude product was dried with anhydrous sodium sulfate and purified by recrystallization through a solvent mixture of ethyl acetate/petroleum ether (1:10, v/v) to finally obtain 3-bromo-5-nitrobenzaldehyde (1.3 g, 82% yield) as white crystals. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 10.09 (s, 1H), 8.79-8.55 (m, 2H), 8.51 (s, 1H).

References

[1] Journal of Medicinal Chemistry, 2018, vol. 61, # 12, p. 5235 - 5244
[2] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5867 - 5869
[3] European Journal of Medicinal Chemistry, 2016, vol. 116, p. 46 - 58
[4] Journal of the American Chemical Society, 2007, vol. 129, # 15, p. 4512 - 4513
[5] Patent: WO2009/153313, 2009, A1. Location in patent: Page/Page column 185

3-BROMO-5-NITROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-5-NITROBENZALDEHYDE Suppliers

Americas 1 China 110 Europe 1 Germany 1 India 8 Japan 1 Switzerland 1 United Kingdom 2 United States 13 Global 138

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View Lastest Price from 3-BROMO-5-NITROBENZALDEHYDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 3-Bromo-5-nitrobenzaldehyde 355134-13-3
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-08

Henan Aochuang Chemical Co.,Ltd.

Product: 3-BROMO-5-NITROBENZALDEHYDE 355134-13-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

Career Henan Chemical Co

Product: 3-BROMO-5-NITROBENZALDEHYDE 355134-13-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

355134-13-3, 3-BROMO-5-NITROBENZALDEHYDERelated Search:

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE 3-Bromo-5-nitrobenzoic acid 3-BROMO-5-NITROBENZALDEHYDE 5-BroMo-3-nitrosalicylaldehyde 3-BROMO-5-NITROBENZAMIDE 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE 3-BROMO-4-NITROBENZALDEHYDE 4-BROMO-2-NITROBENZALDEHYDE 4-BROMO-3-NITRO-BENZALDEHYDE 2-NITRO 5-BROMO-BENZALDEHYDE 3-BROMO-4-METHYL-5-NITROBENZOIC ACID RARECHEM AL BE 0950 CHEMBRDG-BB 6625984 5'-BROMO-2'-HYDROXY-3'-NITROPROPIOPHENONE 1-BROMO-2-NITROBENZALDEHYDE-D4 3-bromo-2-nitrobenzaldehyde 2-Bromo-6-nitrobenzaldehyde 1-BROMO-4-NITROBENZALDEHYDE-D4

3-BROMO-5-NITROBENZALDEHYDE

3-Bromo-5-nitrobenzaldehyde 95%

3-Fluoro-5-nitrobenzaldehyde

Benzaldehyde,3-bromo-5-nitro-

3-BroMo-5-nitrobenzaldehyde, 97+%

3-Bromo-5-formylnitrobenzene

3-Nitro-5-bromo-benzaldehyde

355134-13-3

355134-13-1

Nitro CompoundsChemical Synthesis

Aldehydes

C7Organic Building Blocks

Carbonyl Compounds

New Products for Chemical Synthesis

Nitrogen Compounds

Organic Building Blocks