ChemicalBook > CAS DataBase List > 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid

1-N-Cbz-3-Methylpiperidine-3-carboxylic acid

Product Name
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid
CAS No.
174543-78-3
Chemical Name
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid
Synonyms
1-N-Cbz-3-Methylpiperidine-3-carboxylic;1-Cbz-3-Methylpiperidine-3-carboxylic Acid;1-Cbz-3-methyl-3-piperidinecarboxylic acid;N-Cbz-3-Methylpiperidine-3-carboxylic acid;1-N-Cbz-3-Methylpiperidine-3-carboxylic acid;1-Cbz-3-methyl-3-piperidinecarboxylic acid - [M13677];1-[(benzyloxy)carbonyl]-3-methylpiperidine-3-carboxylic acid;3-Methyl-1,3-piperidinedicarboxylic acid 1-(phenylmethyl) ester;1,3-Piperidinedicarboxylic acid, 3-methyl-, 1-(phenylmethyl) ester
CBNumber
CB61503942
Molecular Formula
C15H19NO4
Formula Weight
277.32
MOL File
174543-78-3.mol
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1-N-Cbz-3-Methylpiperidine-3-carboxylic acid Property

Boiling point:
440.3±45.0 °C(Predicted)
Density 
1.224
storage temp. 
Store at room temperature
pka
4.52±0.20(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C227923
Product name
1-N-Cbz-3-Methylpiperidine-3-carboxylicAcid
Packaging
500mg
Price
$130
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-1-QX
Product name
1-[(Benzyloxy)carbonyl]-3-methylpiperidine-3-carboxylic acid
Purity
97.0%
Packaging
250mg
Price
$140
Updated
2021/12/16
AK Scientific
Product number
5153AJ
Product name
1-N-Cbz-3-methylpiperidine-3-carboxylicacid
Packaging
5g
Price
$471
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0117377
Product name
1-N-CBZ-3-METHYL-PIPERIDINE-3-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$501.62
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC150111
Product name
1-N-Cbz-3-methyl-piperidine-3-carboxylicacid
Packaging
1g
Price
$582
Updated
2021/12/16
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1-N-Cbz-3-Methylpiperidine-3-carboxylic acid Chemical Properties,Usage,Production

Synthesis

664364-60-7

174543-78-3

Step C: 3-Benzyl 3-ethyl-3-methylpiperidine-1,3-dicarboxylate (3.0 g, 10.0 mmol) was dissolved in ethanol (15 mL) and aqueous LiOH solution (15.0 mL, 30.1 mmol) was added. The reaction mixture was stirred at 86 °C for 1 hour. After completion of the reaction, ethanol was removed by distillation under reduced pressure. Ether (30 mL) was added to the residue for extraction and the aqueous layer was separated. The aqueous layer was acidified to pH 3-4 with saturated potassium bisulfate solution and then extracted with ethyl acetate (50 mL). The organic layer was washed with brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give 1-(benzyloxycarbonyl)-3-methylpiperidine-3-carboxylic acid (2.6 g, 92% yield) as an oil.

References

[1] Patent: WO2009/140320, 2009, A1. Location in patent: Page/Page column 73
[2] Patent: US2006/149070, 2006, A1. Location in patent: Page/Page column 41

1-N-Cbz-3-Methylpiperidine-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid manufacturers

Shanghai Rlavie Technology Co ltd
Product
1-Cbz-3-Methylpiperidine-3-carboxylic Acid 174543-78-3
Price
US $0.00/KG
Min. Order
0.001KG
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-05-10

174543-78-3, 1-N-Cbz-3-Methylpiperidine-3-carboxylic acidRelated Search:

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  • 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid
  • 3-Methyl-1,3-piperidinedicarboxylic acid 1-(phenylmethyl) ester
  • 1-[(benzyloxy)carbonyl]-3-methylpiperidine-3-carboxylic acid
  • N-Cbz-3-Methylpiperidine-3-carboxylic acid
  • 1-Cbz-3-methyl-3-piperidinecarboxylic acid
  • 1-Cbz-3-Methylpiperidine-3-carboxylic Acid
  • 1,3-Piperidinedicarboxylic acid, 3-methyl-, 1-(phenylmethyl) ester
  • 1-N-Cbz-3-Methylpiperidine-3-carboxylic
  • 1-Cbz-3-methyl-3-piperidinecarboxylic acid - [M13677]
  • 174543-78-3