Uses
ChemicalBook > CAS DataBase List > 4-Methylbenzenesulfonhydrazide

4-Methylbenzenesulfonhydrazide

Uses
Product Name
4-Methylbenzenesulfonhydrazide
CAS No.
1576-35-8
Chemical Name
4-Methylbenzenesulfonhydrazide
Synonyms
TSH;P-TOLUENESULFONYL HYDRAZIDE;PTSH;TOSYLHYDRAZIDE;Tosylhydrazine;TOLUENE-4-SULFONIC ACID HYDRAZIDE;P-TOLUENESULFONHYDRAZIDE;P-TOLUENESULFONYLHYDRAZINE;Toluol-4-sulfonohydrazid;p-Toluenesulfonohydrazide
CBNumber
CB6156664
Molecular Formula
C7H10N2O2S
Formula Weight
186.23
MOL File
1576-35-8.mol
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4-Methylbenzenesulfonhydrazide Property

Melting point:
103-108 °C(lit.)
Boiling point:
340.5±35.0 °C(Predicted)
Density 
1.42g/cm3
vapor pressure 
0Pa at 20℃
refractive index 
1.5400 (estimate)
Flash point:
60°C
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
5g/l
form 
Powder
pka
9.39±0.10(Predicted)
color 
White or off-white to slightly grayish
Water Solubility 
5 g/L (15 ºC)
Sensitive 
Moisture Sensitive
BRN 
610130
Stability:
Light Sensitive
InChIKey
ICGLPKIVTVWCFT-UHFFFAOYSA-N
LogP
0.55 at 25℃
CAS DataBase Reference
1576-35-8(CAS DataBase Reference)
EPA Substance Registry System
Benzenesulfonic acid, 4-methyl-, hydrazide (1576-35-8)
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Safety

Hazard Codes 
F,Xn
Risk Statements 
11-22-44-2017/11/22
Safety Statements 
16-26
RIDADR 
UN 3226 4.1
WGK Germany 
3
RTECS 
MW0210000
TSCA 
Yes
HazardClass 
4.1
PackingGroup 
II
HS Code 
29280090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
132004
Product name
p-Toluenesulfonyl hydrazide
Purity
97%
Packaging
25g
Price
$54.9
Updated
2024/03/01
Sigma-Aldrich
Product number
132004
Product name
p-Toluenesulfonyl hydrazide
Purity
97%
Packaging
100g
Price
$105
Updated
2024/03/01
Sigma-Aldrich
Product number
RAB0502
Product name
Human Thyroid Stimulating Hormone ELISA Kit
Purity
for serum, plasma, cell culture supernatants and urine
Packaging
1kit
Price
$552
Updated
2024/03/01
Alfa Aesar
Product number
A13529
Product name
p-Toluenesulfonyl hydrazide, 98%
Packaging
25g
Price
$29.8
Updated
2024/03/01
Alfa Aesar
Product number
A13529
Product name
p-Toluenesulfonyl hydrazide, 98%
Packaging
100g
Price
$63.6
Updated
2024/03/01
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4-Methylbenzenesulfonhydrazide Chemical Properties,Usage,Production

Uses

p-Toluenesulfonyl Hydrazide is a reactant that has been used in the synthesis of paspaline.

Chemical Properties

white to off-white powder

Uses

4-Methylbenzenesulfonhydrazide was widely used reagent for the preparation of tosylhydrazones.

Application

p-Toluenesulfonyl hydrazide is used as a reagent for the preparation of tosylhydrazones. It was used to prepare dipyrazolo[1,5-a:4',3'-c]pyridines and 1,2,3-selenadiazole derivatives.

Reactions

4-Methylbenzenesulfonhydrazide as hydrogen donor in reduction reactions:A base-mediated semihydrogenation of ynamides using 4-Methylbenzenesulfonhydrazide (p-toluenesulfonyl hydrazide) as an inexpensive and easy-to-handle hydrogen donor provides the thermodynamically unfavorable Z-enamides exclusively without overhydrogenation and reduction of other functional groups.

Flammability and Explosibility

Not classified

Purification Methods

Dissolve the 4-Methylbenzenesulfonhydrazide in hot MeOH (~1g/4mL), filter through Celite and precipitate the material by adding 2-2.5 volumes of distilled H2O. Dry it in air or in a vacuum. [Fiedman et al. Org Synth Coll Vol V 1055 1973, Beilstein 11 II 66.]

4-Methylbenzenesulfonhydrazide Preparation Products And Raw materials

Raw materials

Hydrazine sulfate Tosyl chloride

Preparation Products

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4-Methylbenzenesulfonhydrazide Suppliers

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View Lastest Price from 4-Methylbenzenesulfonhydrazide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Methylbenzenesulfonhydrazide 1576-35-8
Price
US $99.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-10
Baoji Guokang Bio-Technology Co., Ltd.
Product
4-Methylbenzenesulfonhydrazide 1576-35-8
Price
US $42.00/KG
Min. Order
25KG
Purity
98%
Supply Ability
1-10mt
Release date
2021-06-04
Shouguang Nuomeng Chemical Co Ltd.
Product
P-Toluenesulfonyl hydrazine, TSH, 4-Methylbenzenesulfonhydrazide 1576-35-8
Price
US $6200.00/T
Min. Order
1KG
Purity
98%
Supply Ability
200 tons per month
Release date
2020-07-18

1576-35-8, 4-MethylbenzenesulfonhydrazideRelated Search:

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