4-Methylbenzenesulfonhydrazide

Uses

Product Name: 4-Methylbenzenesulfonhydrazide
CAS No.: 1576-35-8
Chemical Name: 4-Methylbenzenesulfonhydrazide
Synonyms: TSH;P-TOLUENESULFONYL HYDRAZIDE;PTSH;TOSYLHYDRAZIDE;Tosylhydrazine;TOLUENE-4-SULFONIC ACID HYDRAZIDE;P-TOLUENESULFONHYDRAZIDE;P-TOLUENESULFONYLHYDRAZINE;Toluol-4-sulfonohydrazid;p-Toluenesulfonohydrazide
CBNumber: CB6156664
Molecular Formula: C7H10N2O2S
Formula Weight: 186.23
MOL File: 1576-35-8.mol

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4-Methylbenzenesulfonhydrazide Property

Melting point:: 103-108 °C(lit.)
Boiling point:: 340.5±35.0 °C(Predicted)
Density: 1.42g/cm3
vapor pressure: 0Pa at 20℃
refractive index: 1.5400 (estimate)
Flash point:: 60°C
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: 5g/l
form: Powder
pka: 9.39±0.10(Predicted)
color: White or off-white to slightly grayish
Water Solubility: 5 g/L (15 ºC)
Sensitive: Moisture Sensitive
BRN: 610130
Stability:: Light Sensitive
InChIKey: ICGLPKIVTVWCFT-UHFFFAOYSA-N
LogP: 0.55 at 25℃
CAS DataBase Reference: 1576-35-8(CAS DataBase Reference)
EPA Substance Registry System: Benzenesulfonic acid, 4-methyl-, hydrazide (1576-35-8)

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Safety

Hazard Codes: F,Xn
Risk Statements: 11-22-44-2017/11/22
Safety Statements: 16-26
RIDADR: UN 3226 4.1
WGK Germany: 3
RTECS: MW0210000
TSCA: Yes
HazardClass: 4.1
PackingGroup: II
HS Code: 29280090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 132004
Product name: p-Toluenesulfonyl hydrazide
Purity: 97%
Packaging: 25g
Price: $54.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 132004
Product name: p-Toluenesulfonyl hydrazide
Purity: 97%
Packaging: 100g
Price: $105
Updated: 2024/03/01

Sigma-Aldrich

Product number: RAB0502
Product name: Human Thyroid Stimulating Hormone ELISA Kit
Purity: for serum, plasma, cell culture supernatants and urine
Packaging: 1kit
Price: $552
Updated: 2024/03/01

Alfa Aesar

Product number: A13529
Product name: p-Toluenesulfonyl hydrazide, 98%
Packaging: 25g
Price: $29.8
Updated: 2024/03/01

Alfa Aesar

Product number: A13529
Product name: p-Toluenesulfonyl hydrazide, 98%
Packaging: 100g
Price: $63.6
Updated: 2024/03/01

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4-Methylbenzenesulfonhydrazide Chemical Properties,Usage,Production

Uses

p-Toluenesulfonyl Hydrazide is a reactant that has been used in the synthesis of paspaline.

Chemical Properties

white to off-white powder

Uses

4-Methylbenzenesulfonhydrazide was widely used reagent for the preparation of tosylhydrazones.

Application

p-Toluenesulfonyl hydrazide is used as a reagent for the preparation of tosylhydrazones. It was used to prepare dipyrazolo[1,5-a:4',3'-c]pyridines and 1,2,3-selenadiazole derivatives.

Reactions

4-Methylbenzenesulfonhydrazide as hydrogen donor in reduction reactions:A base-mediated semihydrogenation of ynamides using 4-Methylbenzenesulfonhydrazide (p-toluenesulfonyl hydrazide) as an inexpensive and easy-to-handle hydrogen donor provides the thermodynamically unfavorable Z-enamides exclusively without overhydrogenation and reduction of other functional groups.

Flammability and Explosibility

Not classified

Purification Methods

Dissolve the 4-Methylbenzenesulfonhydrazide in hot MeOH (~1g/4mL), filter through Celite and precipitate the material by adding 2-2.5 volumes of distilled H2O. Dry it in air or in a vacuum. [Fiedman et al. Org Synth Coll Vol V 1055 1973, Beilstein 11 II 66.]

4-Methylbenzenesulfonhydrazide Preparation Products And Raw materials

Raw materials

Hydrazine sulfate Tosyl chloride

Preparation Products

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4-Methylbenzenesulfonhydrazide Suppliers

Belgium 1 Canada 1 China 468 Europe 4 Germany 6 India 15 Japan 4 Switzerland 1 The Netherlands 1 United Kingdom 9 United States 33 Global 543

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
ProdList: 6896
Advantage: 91

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View Lastest Price from 4-Methylbenzenesulfonhydrazide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 4-Methylbenzenesulfonhydrazide 1576-35-8
Price: US $99.00-35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-10

Baoji Guokang Bio-Technology Co., Ltd.

Product: 4-Methylbenzenesulfonhydrazide 1576-35-8
Price: US $42.00/KG
Min. Order: 25KG
Purity: 98%
Supply Ability: 1-10mt
Release date: 2021-06-04

Shouguang Nuomeng Chemical Co Ltd.

Product: P-Toluenesulfonyl hydrazine, TSH, 4-Methylbenzenesulfonhydrazide 1576-35-8
Price: US $6200.00/T
Min. Order: 1KG
Purity: 98%
Supply Ability: 200 tons per month
Release date: 2020-07-18

1576-35-8, 4-MethylbenzenesulfonhydrazideRelated Search:

p-Toluenesulfonyl semicarbazide Tosylmethyl isocyanide Toluenesulfonamide p-Anisaldehyde 4-Methoxyphenol 4-Methylphenylsulfonylurea p-Anisidine Tosyl azide 4-Nitrobenzonitrile 4-Methoxybenzyl cyanide p-Toluenesulfonamide p-Toluidine Tosyl chloride Maleic hydrazide antioxidant 1024 1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

n-toluolsulphonylhydrazine

p-toluenesulfohydrazide

p-tolylsulfonyl-hydrazin

4-METHYL-1-BENZENESULFONYL HYDRAZIDE

P-Benzene Sulfonyl Hydrazine

p-Toluenesulfonic acid hydrazide, p-Toluenesulfonyl hydrazide, Tosylhydrazide

Foamer TSH

p-Toluenesulfonhydrazide, p-Toluenesulfonic acid hydrazide, p-Toluenesulfonyl hydrazide, Tosylhydrazide

p-Toluenesulfonhydrazide ,95%

1-Tosylhydrazine

p-Methylbenzenesulfonohydrazide

Tosylhydrazine

4-Methylbenzenesulfonhydrazide,97%

p-Toluenesulfonyl hydrazide,p-Toluenesulfonhydrazide, p-Toluenesulfonic acid hydrazide, p-Toluenesulfonyl hydrazide, Tosylhydrazide

4-Methylbenzenesulfo

4-Methylbenzenesulfonhydrazide, 97% 100GR

4-Methylbenzenesulfonhydrazide, 97% 25GR

4-TOLUENESULFONOHYDRAZIDE FOR SYNTHESIS

TSH 4-Methylbenzenesulfonhydrazide

p-Toluenesulfonyl hydrazide 97%

p-Toluenesulfonyl hydrazide, 98%+

Thyroid Stimulating Hormone (TSH) SA ELISA Kit

ANTI-TSH antibody produced in mouse

Human Thyroid Stimulating Hormone ELISA Kit

P-Toluenesulfonyl Hydrazide (TSH)

<i>p</i>-Toluenesulfonyl Hydrazide

P-Toluenesulfonyl hydrazine, TSH, 4-Methylbenzenesulfonhydrazide

Posaconazole Impurity DBGS Free Base

4-Methylbenzenesulfonhydrazide

4-METHYLBENZENESULFONYL HYDRAZIDE

4-TOLUENESULFONYL HYDRAZIDE

4-TOLUENESULFONIC ACID HYDRAZIDE

4-TOLUENESULFONOHYDRAZIDE

LABOTEST-BB LT00071719

P-TOLYLSULFONYLHYDRAZINE

P-TOLYL HYDRAZIDE

P-TOLUENESULPHONYL HYDRAZIDE

P-TOLUENESULFONYLHYDRAZINE

P-TOLUENESULFONIC ACID HYDRAZIDE

P-TOLUENESULFONYL HYDRAZIDE

P-TOLUENESULFONHYDRAZIDE

SPECS AC-907/25014186

TSH

TOLUENE-4-SULFONIC ACID HYDRAZIDE

TOLUENE-4-SULPHONHYDRAZIDE

toluene-4-sulphonohydrazide

TOLUENE-4-SULFONOHYDRAZIDE

TOSYLHYDRAZIDE

4-Methylbenzenesulphonyl hydrazide

p-Toluenesulfonohydrazide

p-Toluenesulphonohydrazide

PTSH

TOLUENE-P-SULFONYL HYDRAZIDE (TSH)

PARA-TOLUENESULFONHYDRAZIDE, 99%

P-TOLUENESULFONYL HYDRAZIDE,97%

P-Toluenesulfonyl hydrazide (PTSH)

4-methyl-benzenesulphonic acid, hydrazine

PARA-TOLUENESULPHONOHYDRAZIDE