5-Bromo-2-chloropyridine

Product Name: 5-Bromo-2-chloropyridine
CAS No.: 53939-30-3
Chemical Name: 5-Bromo-2-chloropyridine
Synonyms: N-methyl-1-(pyridin-3-yl)methanamine;CL025;2-CHLORO-5-BROMOPYRIDINE;5-BROMO-2-CHLOROPYRIDINE;3-Bromo-6-chloropyridine;2-cholro-5-broMopyridine;5-Bromo-2-chloro pyridne;5-bromo-2-chlorolpyridine;PYRIDINE, 5-BROMO-2-CHLORO-;2-chloro -5-pyridyl broMide
CBNumber: CB6177511
Molecular Formula: C5H3BrClN
Formula Weight: 192.44
MOL File: 53939-30-3.mol

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5-Bromo-2-chloropyridine Property

Melting point:: 65-69 °C (lit.)
Boiling point:: 208.1±20.0 °C(Predicted)
Density: 1.7783 (rough estimate)
refractive index: 1.5400 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -2.25±0.10(Predicted)
form: Crystalline Powder or Crystals
color: Off-white
BRN: 108887
InChI: InChI=1S/C5H3BrClN/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKey: PEAOEIWYQVXZMB-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=C(Br)C=C1
CAS DataBase Reference: 53939-30-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39-36/37/39
WGK Germany: 3
Hazard Note: Irritant
TSCA: T
HazardClass: IRRITANT, IRRITANT-HARMFUL
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 551902
Product name: 5-Bromo-2-chloropyridine
Purity: 95%
Packaging: 25g
Price: $125
Updated: 2024/03/01

Sigma-Aldrich

Product number: 551902
Product name: 5-Bromo-2-chloropyridine
Purity: 95%
Packaging: 5g
Price: $55.7
Updated: 2023/06/20

TCI Chemical

Product number: B2329
Product name: 5-Bromo-2-chloropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $24
Updated: 2024/03/01

TCI Chemical

Product number: B2329
Product name: 5-Bromo-2-chloropyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $94
Updated: 2024/03/01

Alfa Aesar

Product number: B24862
Product name: 5-Bromo-2-chloropyridine, 98%
Packaging: 5g
Price: $31.65
Updated: 2024/03/01

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5-Bromo-2-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromo-2-chloropyridine may be used in the preparation of following compounds:

Amino-2-chloropyridine via palladium-catalyzed amination.
5-Bromo-2-fluoropyridine via halogen-exchange reaction using anhydrous potassium fluoride.
2-Chloro-5-(2,5-dimethoxyphenyl)pyridine via Suzuki coupling with 2,5-dimethoxyphenylboronic acid.

Synthesis

6-Chloro-pyridin-3-ylamine was dissolved slowly with constant stirring in 48% HBr solution (50 mL) at r.t. and then the solution was cooled to -10 °C. A solution of sodium nitrite in cold water was added dropwise at -10 °C with constant stirring over 2 h, followed by a solution of copper (I) bromide in 48% HBr dropwise. The mixture was then stirred at r.t. until complete. The mixture was neutralized with sodium carbonate and extracted with ethyl acetate. The organic phase was washed with brine, dried over sodium sulfate, and concentrated. The residue was purified by column chromatography on silica gel (60-120 mesh) eluting with 1% ethyl acetate/petroleum ether to afford 5- bromo-2-chloropyridine.

5-Bromo-2-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloropyridine-5-boronic acid

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5-Bromo-2-chloropyridine Suppliers

Americas 1 Belgium 2 China 428 Europe 3 France 4 Germany 8 India 54 Ireland 1 Japan 2 Jordan 1 Poland 2 Russia 1 South Korea 1 Switzerland 3 Ukraine 3 United Kingdom 21 United States 64 Global 599

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
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Advantage: 66

Alfa Aesar, Thermo Fisher Scientific

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CHEMOS GmbH & Co. KG

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Email: chemos@chemos.de
Country: Germany
ProdList: 6727
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ratiochem GmbH

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ABCR GmbH & CO. KG

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ProdList: 6831
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PARAGOS

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ACTIVATE SCIENTIFIC GmbH

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Country: Germany
ProdList: 2856
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Service Chemical Inc.

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ProdList: 6350
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View Lastest Price from 5-Bromo-2-chloropyridine manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 2-Chloro-5-bromopyridine 53939-30-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-05

Henan Fengda Chemical Co., Ltd

Product: 2-Chloro-5-bromopyridine 53939-30-3
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

Hebei Mojin Biotechnology Co., Ltd

Product: 2-Chloro-5-bromopyridine 53939-30-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-08

53939-30-3, 5-Bromo-2-chloropyridineRelated Search:

1-Hexadecylpyridinium bromide 2-Chloro-5-chloromethylpyridine Clopidol 2-Chloro-5-fluoropyridine 2-Chloro-3-cyanopyridine 5-Amino-2-chloropyridine 2-chloro-5-cyanopyridine 3-Bromo-6-chloro-2-methylpyridine 6-Chloro-2-methyl-3-nitropyridine 2-Chloro-5-hydroxypyridine 2-CHLORO-5-METHOXYPYRIDINE 2-Chloro-5-nitropyridine 2-Chloro-5-iodopyridine 5-Bromo-2-chlorobenzoic acid pyridinium Chlorochromate Difluorochloromethane Bromine 2-Chloropyridine

5-BROMO-2-CHLOROPYRIDINE

2-CHLORO-5-BROMOPYRIDINE

PYRIDINE, 5-BROMO-2-CHLORO-

3-Bromo-6-chloropyridine

5-bromo-2-chlorolpyridine

5-Bromo-2-chloropyridine, 98+%

5-BROMO-2-CHLOROPYRIDINE 98%

2-CHLORO-5-BROMOPYRIDINE 5-BROMO-2-CHLORO-PYRIDINE

5-Bromo-2-chloropyridine 2-Chloro-5-Bromopyridine

N-methyl-1-(pyridin-3-yl)methanamine

2-cholro-5-broMopyridine

2-chlorine-5- broMine Pyridine

2-chloro -5-pyridyl broMide

5-broMo -2-chlorine pyridine

CL025

2-CHLORO-5-BROMOPYRIDINE 5-BROMO-2-CHLORO-PYR

5-BroMo-2-chloropyridine, 97+%

5-Bromo-2-chloro pyridne

5-Bromo-2-chloropyridine &gt

5-Bromo-2-chloropyridine ISO 9001：2015 REACH

53939-30-3

53930-30-3

52939-30-3

C5H3BrClN

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Building Blocks

Chloropyridines

Halopyridines

Bromopyridines

Pyridines derivates

Halogenated

Organohalides

Bromopyridines

Chloropyridines

Halopyridines

Boronic Acid

C5Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Variety of halogenated heterocyclic series

blocks

Bromides

Pyridines

Pyridine

pyridine derivative

Pyridine Series

Pyridines, Pyrimidines, Purines and Pteredines

compounds of pyridine

Risdiplam

bc0001