Methyl 3-chloro-4-fluorobenzoate
- Product Name
- Methyl 3-chloro-4-fluorobenzoate
- CAS No.
- 234082-35-0
- Chemical Name
- Methyl 3-chloro-4-fluorobenzoate
- Synonyms
- Chloro-4-fluorobenzoate;methyl 3-Chloro-6-fluorobenzoate;methyl 3-chloro-4-fluorobenzoate;3-Chloro-4-fluoro Methyl benzoate;Benzoic acid, 3-chloro-4-fluoro-, methyl ester
- CBNumber
- CB62546036
- Molecular Formula
- C8H6ClFO2
- Formula Weight
- 188.58
- MOL File
- 234082-35-0.mol
Methyl 3-chloro-4-fluorobenzoate Property
- Boiling point:
- 238℃
- Density
- 1.314
- Flash point:
- 102℃
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid-Liquid Mixture
- InChI
- InChI=1S/C8H6ClFO2/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4H,1H3
- InChIKey
- RUTYNTBIMOCJMW-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=CC=C(F)C(Cl)=C1
Safety
- HS Code
- 2916310090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H350May cause cancer
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M340435
- Product name
- Methyl3-Chloro-4-fluorobenzoate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 079448
- Product name
- Methyl3-chloro-4-fluorobenzoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- 2623-7-X5
- Product name
- Methyl 3-chloro-4-fluorobenzoate
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 076102
- Product name
- Methyl 3-chloro-4-fluorobenzoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $93
- Updated
- 2021/12/16
- Product number
- W4715
- Product name
- Methyl3-chloro-4-fluorobenzoate
- Packaging
- 10g
- Price
- $134
- Updated
- 2021/12/16
Methyl 3-chloro-4-fluorobenzoate Chemical Properties,Usage,Production
Chemical Properties
off-white powder
Uses
Methyl 3-chloro-4-fluorobenzoate is a halogenated organic compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.
Synthesis
67-56-1
65055-17-6
234082-35-0
Example 1 Preparation of methyl 3-chloro-4-fluorobenzoate In a 250 mL four-necked round-bottomed flask assembled with a mechanical stirrer, condenser tube and thermometer, 86.5 g of 3-chloro-4-fluorobenzoyl chloride was added. 28.1 g of anhydrous methanol was added slowly through a constant pressure dropping funnel. The reaction was exothermic and the temperature was raised to 60 °C spontaneously. The titration rate of methanol was controlled to maintain the reaction temperature at about 60 °C. The reaction mixture was stirred for 1 hour and the excess methanol was removed by distillation. A final 80 g of yellow oily material was obtained as methyl 3-chloro-4-fluorobenzoate in 97.29% yield.
References
[1] Patent: WO2003/95417, 2003, A1. Location in patent: Page/Page column 6
Methyl 3-chloro-4-fluorobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 3-chloro-4-fluorobenzoate manufacturers
- Product
- 3-Chloro-4-fluoro Methyl benzoate 234082-35-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-07
- Product
- Methyl 3-chloro-4-fluorobenzoate 234082-35-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.5%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 3-Chloro-4-fluoro Methyl benzoate 234082-35-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11