ChemicalBook > CAS DataBase List > 2-Amino-5-bromopyrimidine

2-Amino-5-bromopyrimidine

Product Name
2-Amino-5-bromopyrimidine
CAS No.
7752-82-1
Chemical Name
2-Amino-5-bromopyrimidine
Synonyms
5-BROMOPYRIMIDIN-2-AMINE;RUNA811;NSC 27269;TIMTEC-BB SBB000184;2-Amino-5-bromopyrimide;5-BROMO-2-PYRIMIDINAMINE;2-AMINO-5-BROMOPYRIMIDINE;5-BROMO-2-AMINOPYRIMIDINE;2-Amino-5-Bormopyrimidine;5-Bromopyrimidine-2-amine
CBNumber
CB6289294
Molecular Formula
C4H4BrN3
Formula Weight
174
MOL File
7752-82-1.mol
More
Less

2-Amino-5-bromopyrimidine Property

Melting point:
241-243 °C (lit.)
Boiling point:
340.7±34.0 °C(Predicted)
Density 
1.844±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Crystalline Powder, Crystals or Flakes
pka
1.93±0.10(Predicted)
color 
White to light beige
Water Solubility 
Insoluble
InChI
InChI=1S/C4H4BrN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)
InChIKey
UHRHPPKWXSNZLR-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Br)C=N1
CAS DataBase Reference
7752-82-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,N,Xi
Risk Statements 
22-36-50/53
Safety Statements 
26-60-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
Hazard Note 
Harmful
HazardClass 
IRRITANT, IRRITANT-HARMFUL
PackingGroup 
III
HS Code 
29335995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
303526
Product name
2-Amino-5-bromopyrimidine
Purity
98%
Packaging
1g
Price
$20.56
Updated
2025/07/31
Sigma-Aldrich
Product number
303526
Product name
2-Amino-5-bromopyrimidine
Purity
98%
Packaging
5g
Price
$34.51
Updated
2025/07/31
TCI Chemical
Product number
A1920
Product name
2-Amino-5-bromopyrimidine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$41
Updated
2025/07/31
TCI Chemical
Product number
A1920
Product name
2-Amino-5-bromopyrimidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$172
Updated
2025/07/31
Usbiological
Product number
B2840
Product name
5-Bromo-2-aminopyrimidine
Packaging
10g
Price
$425
Updated
2021/12/16
More
Less

2-Amino-5-bromopyrimidine Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

2-Amino-5-bromopyrimidine was employed:

  • in synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites
  • in synthesis of 2-phthalimido-5-bromopyrimidine
  • as intermediate for the preparation of sulfanilamides and amino acids containing the pyrimidine ring system. The products are potential antiviral agents

General Description

Crystal structure of 2-amino-5-bromopyrimidine was studied.

Synthesis

The synthesis of 2-Amino-5-bromopyrimidine is as follows:The 2-aminopyrimidine (2.5g, 26.29mmol) was dissolved in acetonitrile (25mL) was added N- bromosuccinimide (4.6g, 27.9mmol) under ice-cooling, stirred in the dark overnight at room temperature. Recovery of the solvent under reduced pressure, washed with water (100 mL) was washed, filtered off with suction, and dried in vacuo to give a white solid. Yield: 97%.

storage

Store in cool, well ventilated area. Keep container tightly closed. Light sensitive. Store under argon.

References

[1] Journal of Organic Chemistry, 2012, vol. 77, # 16, p. 6908 - 6916
[2] European Journal of Organic Chemistry, 2018, vol. 2018, # 43, p. 5921 - 5934
[3] Patent: CN106588884, 2017, A. Location in patent: Paragraph 0210; 0214; 0215; 0216
[4] Synthesis, 2004, # 17, p. 2809 - 2812
[5] Chemical Communications, 2017, vol. 53, # 44, p. 5997 - 6000

2-Amino-5-bromopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Amino-5-bromopyrimidine Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
More
Less

View Lastest Price from 2-Amino-5-bromopyrimidine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Amino-5-bromopyrimidine 7752-82-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-29
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Amino-5-bromopyrimidine 7752-82-1
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-12
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-5-bromopyrimidine 7752-82-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-14

7752-82-1, 2-Amino-5-bromopyrimidineRelated Search:


  • TIMTEC-BB SBB000184
  • 5-BROMOPYRIMIDIN-2-AMINE
  • 2-AMINO-5-BROMOPYRIMIDINE
  • 5-BROMO-2-PYRIMIDINAMINE
  • 5-BROMO-2-PYRIMIDINYLAMINE
  • 5-BROMO-2-AMINOPYRIMIDINE
  • 5-BROMOPYRIMIDIN-2-YLAMINE
  • 2-Amino-5-Bormopyrimidine
  • 2-Pyrimidinamine, 5-bromo-
  • 2-Amino-5-bromopyrimide
  • Pyrimidine, 2-amino-5-bromo-
  • 2-Amino-5-bromopyrimidine ,98%
  • 5-Bromopyrimidine-2-amine
  • 2-Amino-5-bromopyrimidine,97%
  • 5-bromopyrimidin-2-amine(SALTDATA: FREE)
  • NSC 27269
  • 5-Bromopyrimidin-2-amine, 2-Amino-5-bromo-1,3-diazine
  • 2-aMino-5-broMopyriMidine(5-broMo-2-aMinopyriMidine)
  • 2 - aMino - 5 - broMine pyriMidine
  • 2-Amino-5-bromopyrimidine &gt
  • RUNA811
  • 2-Amino-5-bromopyrimidine ISO 9001:2015 REACH
  • 5-Bromopyrimidin-2-amine, 98%
  • 7752-82-1
  • 7751-82-1
  • C4H4BrN3MW17400
  • C4H4BrN3
  • Bases & Related Reagents
  • Nucleotides
  • Halides
  • Pyrazines, Pyrimidines & Pyridazines
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines
  • PyrimidinesHeterocyclic Building Blocks
  • Heterocycle-Pyrimidine series
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Organohalides
  • Pyrimidine
  • Aromatics Compounds
  • Aromatics
  • FINE Chemical & INTERMEDIATES
  • Amines and Anilines
  • Heterocycles
  • bc0001