Mal-PEG4-NHS ester
- Product Name
- Mal-PEG4-NHS ester
- CAS No.
- 1325208-25-0
- Chemical Name
- Mal-PEG4-NHS ester
- Synonyms
- MAL-PEG4-Osu;Mal-PEG4-NHS ester;Mal-PEG4-CH2CH2COONHS;2,5-dioxopyrrolidin-1-yl1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12-tetraoxapentadecan-15-oate;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate;2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate - [D82329];4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB63062539
- Molecular Formula
- C19H26N2O10
- Formula Weight
- 442.42
- MOL File
- 1325208-25-0.mol
Mal-PEG4-NHS ester Property
- Boiling point:
- 580.5±60.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in DCM
- pka
- -2.34±0.20(Predicted)
- form
- Solid-Liquid Mixture
- color
- Off-white to yellow
- InChI
- InChI=1S/C19H26N2O10/c22-15-1-2-16(23)20(15)6-8-28-10-12-30-14-13-29-11-9-27-7-5-19(26)31-21-17(24)3-4-18(21)25/h1-2H,3-14H2
- InChIKey
- TUPOSLKVPPFQGR-UHFFFAOYSA-N
- SMILES
- C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A496025
- Product name
- MAL-PEG4-NHSEster
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- A496025
- Product name
- MAL-PEG4-NHSEster
- Packaging
- 25mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- BP-20554
- Product name
- Mal-PEG4-NHSester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $340
- Updated
- 2021/12/16
- Product number
- POL0002471
- Product name
- MAL-PEG4-NHS ESTER
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $551.25
- Updated
- 2021/12/16
- Product number
- BP-20554
- Product name
- Mal-PEG4-NHSester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $650
- Updated
- 2021/12/16
Mal-PEG4-NHS ester Chemical Properties,Usage,Production
Description
Mal-PEG4-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Uses
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes[1].
IC 50
Non-cleavable Linker
References
[1] Mukthavaram R, et al. Assembly and targeting of liposomal nanoparticles encapsulating quantum dots. Bioconjug Chem. 2011;22(8):1638-1644. DOI:10.1021/bc200201e
Mal-PEG4-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Mal-PEG4-NHS ester manufacturers
- Product
- 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate 1325208-25-0
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- Mal-PEG4-NHS ester 1325208-25-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27