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Mal-PEG4-NHS ester

Product Name
Mal-PEG4-NHS ester
CAS No.
1325208-25-0
Chemical Name
Mal-PEG4-NHS ester
Synonyms
MAL-PEG4-Osu;Mal-PEG4-NHS ester;Mal-PEG4-CH2CH2COONHS;2,5-dioxopyrrolidin-1-yl1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12-tetraoxapentadecan-15-oate;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate;2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate - [D82329];4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB63062539
Molecular Formula
C19H26N2O10
Formula Weight
442.42
MOL File
1325208-25-0.mol
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Mal-PEG4-NHS ester Property

Boiling point:
580.5±60.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Soluble in DCM
pka
-2.34±0.20(Predicted)
form 
Solid-Liquid Mixture
color 
Off-white to yellow
InChI
InChI=1S/C19H26N2O10/c22-15-1-2-16(23)20(15)6-8-28-10-12-30-14-13-29-11-9-27-7-5-19(26)31-21-17(24)3-4-18(21)25/h1-2H,3-14H2
InChIKey
TUPOSLKVPPFQGR-UHFFFAOYSA-N
SMILES
C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A496025
Product name
MAL-PEG4-NHSEster
Packaging
5mg
Price
$90
Updated
2021/12/16
TRC
Product number
A496025
Product name
MAL-PEG4-NHSEster
Packaging
25mg
Price
$310
Updated
2021/12/16
BroadPharm
Product number
BP-20554
Product name
Mal-PEG4-NHSester
Purity
98%
Packaging
100mg
Price
$340
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002471
Product name
MAL-PEG4-NHS ESTER
Purity
95.00%
Packaging
100MG
Price
$551.25
Updated
2021/12/16
BroadPharm
Product number
BP-20554
Product name
Mal-PEG4-NHSester
Purity
98%
Packaging
250mg
Price
$650
Updated
2021/12/16
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Mal-PEG4-NHS ester Chemical Properties,Usage,Production

Description

Mal-PEG4-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes[1].

IC 50

Non-cleavable Linker

References

[1] Mukthavaram R, et al. Assembly and targeting of liposomal nanoparticles encapsulating quantum dots. Bioconjug Chem. 2011;22(8):1638-1644. DOI:10.1021/bc200201e

Mal-PEG4-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG4-NHS ester Suppliers

PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8595
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
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View Lastest Price from Mal-PEG4-NHS ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate 1325208-25-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12
Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG4-NHS ester 1325208-25-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27

1325208-25-0, Mal-PEG4-NHS esterRelated Search:


  • Mal-PEG4-NHS ester
  • 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
  • 2,5-dioxopyrrolidin-1-yl1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12-tetraoxapentadecan-15-oate
  • MAL-PEG4-Osu
  • (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • Mal-PEG4-CH2CH2COONHS
  • (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate - [D82329]
  • 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate
  • 1325208-25-0
  • peg