ChemicalBook > CAS DataBase List > 1-Hydroxy-2-naphthoic acid

1-Hydroxy-2-naphthoic acid

Product Name
1-Hydroxy-2-naphthoic acid
CAS No.
86-48-6
Chemical Name
1-Hydroxy-2-naphthoic acid
Synonyms
NSC 3717;Xinafoic acid.;RARECHEM AL BE 0359;2-Carboxy-1-naphthol;1-Hydroxy-2-naphthoi;LABOTEST-BB LT00452757;1-Hydroxy-2-phthoic acid;hydroxy-2-naphthoic acid;1-Hydroxy-2-naphthoicaci;1-hydroxy-β-naphthoic acid
CBNumber
CB6317591
Molecular Formula
C11H8O3
Formula Weight
188.18
MOL File
86-48-6.mol
More
Less

1-Hydroxy-2-naphthoic acid Property

Melting point:
195-200 °C (dec.) (lit.)
Boiling point:
283.17°C (rough estimate)
Density 
1.2100 (rough estimate)
refractive index 
1.6310 (estimate)
Flash point:
150 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: freely soluble
form 
Powder or Crystals
pka
3.02±0.30(Predicted)
color 
White to slightly pink to tan
Water Solubility 
SOLUBLE IN HOT WATER
Merck 
14,4834
BRN 
974438
InChIKey
SJJCQDRGABAVBB-UHFFFAOYSA-N
LogP
3.196 (est)
CAS DataBase Reference
86-48-6(CAS DataBase Reference)
EPA Substance Registry System
1-Hydroxy-2-naphthoic acid (86-48-6)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-37
WGK Germany 
3
TSCA 
Yes
HS Code 
29182910
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
109630
Product name
1-Hydroxy-2-naphthoic acid
Purity
≥97.0%
Packaging
5g
Price
$34.1
Updated
2024/03/01
Sigma-Aldrich
Product number
109630
Product name
1-Hydroxy-2-naphthoic acid
Purity
≥97.0%
Packaging
100g
Price
$59.5
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$32
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$322
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
100g
Price
$97
Updated
2024/03/01
More
Less

1-Hydroxy-2-naphthoic acid Chemical Properties,Usage,Production

Chemical Properties

beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6], C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the 4,7-positions. It is sulfonated by oleum to give the 4-sulfonic and then the 4,7-disulfonic acids. Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol.

Uses

Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes.

Uses

It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Definition

ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate.

Preparation

Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product.

General Description

1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.

Purification Methods

Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]

1-Hydroxy-2-naphthoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-Hydroxy-2-naphthoic acid Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
More
Less

View Lastest Price from 1-Hydroxy-2-naphthoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Weibang Biotechnology Co., Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01
Shaanxi Dideu Medichem Co. Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KG
Release date
2024-08-07

86-48-6, 1-Hydroxy-2-naphthoic acidRelated Search:


  • LABOTEST-BB LT00452757
  • RARECHEM AL BE 0359
  • Salmeterol Hydroxynaphthoic Acid Impurity (USP)
  • ALPHA-HYDROXYNAPHTHOIC ACID
  • 1-NAPHTHOL-2-CARBOXYLIC ACID
  • 1-HYDROXY-2-NAPHTHOIC ACID
  • 1-HYDROXY-NAPHTHALENE-2-CARBONIC ACID
  • 1-Hydroxy-2-phthoic acid
  • 1-Hydroxy-naphthalene-2-carboxylic acid for synthesis
  • Salmeterol Hydroxynaphthoic Acid Impurity
  • 1-hydroxy-β-naphthoic acid
  • 2-Naphthalenecarboxylic acid, 1-hydroxy-
  • 1-HYDROXYNAPHTHALENE-2-CARBOXYLIC ACID (1-HYDROXY-2-NAPHTHOIC ACID)
  • 1-Hydroxy-2-naphthoic acid, 98+%
  • 2-Carboxy-1-naphthol
  • Hydroxynaphthalene-2-carboxylic acid
  • Naphthol-2-carboxylic acid
  • 1-Hydroxy-2-naphthoic acid,99%
  • 1-Hydroxynaphthalene-2-carboxylic acid, 2-Carboxy-1-hydroxynaphthalene
  • 1-Hydroxy-2-naphthoic acid, 99% 100GR
  • 1-Hydroxy-2-naphthoic acid, 99% 5GR
  • NSC 3717
  • Xinafoic acid.
  • 1-Hydroxy-2-naphthoic acid >=97.0%
  • 1-hydroxy-2-naphthalenecarboxylicaci
  • 1-hydroxy-2-Naphthalenecarboxylicacid
  • hydroxy-2-naphthoic acid
  • 1-Hydroxy-2-naphthoic acid, 97%, for synthesis
  • 1-Hydroxy-2-naphthoicAcid&gt
  • 1-Hydroxy-2-naphthoicaci
  • 1-Hydroxy-2-naphthoic acid ISO 9001:2015 REACH
  • 1-Hydroxy-2-naphthoi
  • 86-48-6
  • 84-48-6
  • HOC10H6COOH
  • C11H7O3
  • Organic Building Blocks
  • Building Blocks
  • Carboxylic Acids
  • Carbonyl Compounds
  • C11 to C12
  • CARBOXYLIC ACID
  • Aromatics
  • Intermediates of Dyes and Pigments
  • bc0001