ChemicalBook > CAS DataBase List > 1-Hydroxy-2-naphthoic acid

1-Hydroxy-2-naphthoic acid

Product Name
1-Hydroxy-2-naphthoic acid
CAS No.
86-48-6
Chemical Name
1-Hydroxy-2-naphthoic acid
Synonyms
NSC 3717;Xinafoic acid.;RARECHEM AL BE 0359;2-Carboxy-1-naphthol;1-Hydroxy-2-naphthoi;LABOTEST-BB LT00452757;1-Hydroxy-2-phthoic acid;hydroxy-2-naphthoic acid;1-Hydroxy-2-naphthoicaci;1-hydroxy-β-naphthoic acid
CBNumber
CB6317591
Molecular Formula
C11H8O3
Formula Weight
188.18
MOL File
86-48-6.mol
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1-Hydroxy-2-naphthoic acid Property

Melting point:
195-200 °C (dec.) (lit.)
Boiling point:
283.17°C (rough estimate)
Density 
1.2100 (rough estimate)
refractive index 
1.6310 (estimate)
Flash point:
150 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: freely soluble
form 
Powder or Crystals
pka
3.02±0.30(Predicted)
color 
White to slightly pink to tan
Water Solubility 
SOLUBLE IN HOT WATER
Merck 
14,4834
BRN 
974438
InChIKey
SJJCQDRGABAVBB-UHFFFAOYSA-N
LogP
3.196 (est)
CAS DataBase Reference
86-48-6(CAS DataBase Reference)
EPA Substance Registry System
1-Hydroxy-2-naphthoic acid (86-48-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-37
WGK Germany 
3
TSCA 
Yes
HS Code 
29182910
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
109630
Product name
1-Hydroxy-2-naphthoic acid
Purity
≥97.0%
Packaging
5g
Price
$34.1
Updated
2024/03/01
Sigma-Aldrich
Product number
109630
Product name
1-Hydroxy-2-naphthoic acid
Purity
≥97.0%
Packaging
100g
Price
$59.5
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$32
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$322
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
100g
Price
$97
Updated
2024/03/01
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1-Hydroxy-2-naphthoic acid Chemical Properties,Usage,Production

Chemical Properties

beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6], C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the 4,7-positions. It is sulfonated by oleum to give the 4-sulfonic and then the 4,7-disulfonic acids. Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol.

Uses

Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes.

Uses

It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Definition

ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate.

Preparation

Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product.

General Description

1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.

Purification Methods

Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]

1-Hydroxy-2-naphthoic acid Preparation Products And Raw materials

Raw materials

1-Naphthol Carbon dioxide Water Sodium formate

Preparation Products

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1-Hydroxy-2-naphthoic acid Suppliers

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View Lastest Price from 1-Hydroxy-2-naphthoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Weibang Biotechnology Co., Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01
Shaanxi Dideu Medichem Co. Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KG
Release date
2024-08-07

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