FHPI HCL

Product Name: FHPI HCL
CAS No.: 350228-36-3
Chemical Name: FHPI HCL
Synonyms: FHPI HCL;SB202190 HCL;SB 202190, HYDROCHLORIDE;SB 202190 monohydrochloride hydrate;SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HCL;4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1h-imidazol-2-yl)phenol hydrochloride;4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-iMidazol-2-yl]phenol Monohydrochloride;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HYDROCHLORIDE;4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride hydrate
CBNumber: CB6321057
Molecular Formula: C20H15ClFN3O
Formula Weight: 367.8
MOL File: Mol file

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FHPI HCL Property

storage temp.: -20°C
solubility: DMSO: ≥12mg/mL
form: solid
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S7076
Product name: SB 202190 monohydrochloride hydrate
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $134
Updated: 2024/03/01

Cayman Chemical

Product number: 21201
Product name: SB 202190 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21201
Product name: SB 202190 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Sigma-Aldrich

Product number: S7076
Product name: SB 202190 monohydrochloride hydrate
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $545
Updated: 2024/03/01

Cayman Chemical

Product number: 21201
Product name: SB 202190 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $122
Updated: 2024/03/01

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FHPI HCL Chemical Properties,Usage,Production

Uses

The water soluble form of SB 202190, a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower concentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.

General Description

A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190 (Cat. No. 559388).

Biochem/physiol Actions

SB 202190 monohydrochloride hydrate mediates the phosphorylation of serine in the mutant p53 protein and modulates cell adhesion and prevents cell proliferation in breast cancer cell lines.

FHPI HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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FHPI HCL Suppliers

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350228-36-3, FHPI HCLRelated Search:

SB 202190 Pifithrin-α (PFTα) SB 220025 PRIMA-1 PD 169316 CP 31398 SB 239063 CYCLIC-PIFITHRIN-ALPHA 1H-INDOLE-5-CARBOXAMIDE, 97% JX401 IMIDAZOLE HYDROCHLORIDE

SB202190 HCL

SB 202190, HYDROCHLORIDE

FHPI HCL

4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-iMidazol-2-yl]phenol Monohydrochloride

4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole monohydrochloride hydrate

4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride hydrate

SB 202190 monohydrochloride hydrate

4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HCL

4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HYDROCHLORIDE

SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem

4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1h-imidazol-2-yl)phenol hydrochloride

350228-36-3

C20H15ClFN3O

C20H14FN3OClH