FHPI HCL
- Product Name
- FHPI HCL
- CAS No.
- 350228-36-3
- Chemical Name
- FHPI HCL
- Synonyms
- FHPI HCL;SB202190 HCL;SB 202190, HYDROCHLORIDE;SB 202190 monohydrochloride hydrate;SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HCL;4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1h-imidazol-2-yl)phenol hydrochloride;4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-iMidazol-2-yl]phenol Monohydrochloride;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE HYDROCHLORIDE;4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride hydrate
- CBNumber
- CB6321057
- Molecular Formula
- C20H15ClFN3O
- Formula Weight
- 367.8
- MOL File
- Mol file
FHPI HCL Property
- storage temp.
- -20°C
- solubility
- DMSO: ≥12mg/mL
- form
- solid
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S7076
- Product name
- SB 202190 monohydrochloride hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $134
- Updated
- 2024/03/01
- Product number
- 21201
- Product name
- SB 202190 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 21201
- Product name
- SB 202190 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- S7076
- Product name
- SB 202190 monohydrochloride hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $545
- Updated
- 2024/03/01
- Product number
- 21201
- Product name
- SB 202190 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $122
- Updated
- 2024/03/01
FHPI HCL Chemical Properties,Usage,Production
Uses
The water soluble form of SB 202190, a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower concentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.
General Description
A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190 (Cat. No. 559388).
Biochem/physiol Actions
SB 202190 monohydrochloride hydrate mediates the phosphorylation of serine in the mutant p53 protein and modulates cell adhesion and prevents cell proliferation in breast cancer cell lines.