2-Amino-3-fluorobenzoic acid

Application

Product Name: 2-Amino-3-fluorobenzoic acid
CAS No.: 825-22-9
Chemical Name: 2-Amino-3-fluorobenzoic acid
Synonyms: Diaphonic acid;BUTTPARK 22\01-93;uorobenzenecarboxyL;2-AMino-3-fluorobenz;2-AMINO-3-FLUOROBENZOIC;3-FLUOROANTHRANILIC ACID;3-FluoroanthranilicAcid>2-Amino-3-fluorobenzoicAci;2-AMINO-3-FLUOROBENZOIC ACID;2-Amino-3-Fluoride Benzoic Acids
CBNumber: CB6368755
Molecular Formula: C7H6FNO2
Formula Weight: 155.13
MOL File: 825-22-9.mol

More

Less

2-Amino-3-fluorobenzoic acid Property

Melting point:: 171-172°C
Boiling point:: 294.4±25.0 °C(Predicted)
Density: 1.430±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 4.60±0.10(Predicted)
color: White to Light yellow to Light orange
InChI: InChI=1S/C7H6FNO2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey: KUHAYJJXXGBYBW-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC=CC(F)=C1N
CAS DataBase Reference: 825-22-9(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39-24/25
HazardClass: IRRITANT
HS Code: 29223990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: F0570
Product name: 3-Fluoroanthranilic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: F0570
Product name: 3-Fluoroanthranilic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $107
Updated: 2025/07/31

TRC

Product number: A634628
Product name: 2-Amino-3-fluorobenzoicAcid
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 008762
Product name: 2-Amino-3-fluorobenzoic acid
Purity: 98%
Packaging: 25g
Price: $58
Updated: 2021/12/16

AK Scientific

Product number: L162
Product name: 2-Amino-3-fluorobenzoicacid
Packaging: 1g
Price: $64
Updated: 2021/12/16

More

Less

2-Amino-3-fluorobenzoic acid Chemical Properties,Usage,Production

Application

2-Amino-3-fluorobenzoic acid is a carboxylic acid derivative and can be used as a pharmaceutical intermediate.

Chemical Properties

white to light yellow crystal powder

Synthesis

317-20-4

825-22-9

7-Fluoro-1H-indole-2,3-dione (13.0 g, 78.7 mmol) was used as raw material, which was dissolved in 10N sodium hydroxide solution (125 mL), heated to 70°C and stirred for 1 hour. At the same temperature, 30% hydrogen peroxide solution (25 mL) was added slowly and dropwise over 20 minutes and the reaction continued to be stirred at 70 °C for 1 hour. Upon completion of the reaction, the reaction solution was cooled in an ice bath and concentrated. Subsequently, hydrochloric acid was slowly added to adjust the pH of the solution to 4. The organic phase was extracted with ethyl acetate, and the extract was washed with saturated brine and dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure to give the crude product. The crystals were collected by filtration to finally obtain 2-amino-3-fluorobenzoic acid (7.15 g, 59% yield). The NMR hydrogen spectrum (CDCl3) data were as follows: δ 6.00 (2H, broad single peak), 6.60 (1H, double-triple peak, J = 5.2 Hz, 8.0 Hz), 7.16 (1H, multiple peaks, J = 1.4 Hz, 8.0 Hz, 11.2 Hz), 7.72 (1H, triple-double peaks, J = 1.4 Hz, 8.0 Hz), and one additional hydrogen signal was masked.

References

[1] Organic Syntheses, 2002, vol. 79, p. 196 - 196
[2] Patent: US2003/187014, 2003, A1
[3] Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958, vol. 148, p. 481,488
[4] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 7, p. 2151 - 2163
[5] European Journal of Medicinal Chemistry, 1994, vol. 29, # 10, p. 743 - 751

2-Amino-3-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Amino-3-fluorobenzoic acid Suppliers

Americas 1 Belgium 1 Canada 2 China 291 Europe 5 France 1 Germany 4 India 12 Italy 1 Japan 2 Ukraine 2 United Kingdom 21 United States 52 Global 395

Carbosynth

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6005
Advantage: 58

AF ChemPharm

Tel: --
Fax: --
Email: enquiries@afchempharm.co.uk
Country: United Kingdom
ProdList: 66
Advantage: 58

Melrob Ltd (part of Nordmann)

Tel: --
Fax: --
Email: nquiries@melrob.com
Country: United Kingdom
ProdList: 3065
Advantage: 58

Apollo Scientific Ltd

Tel: --
Fax: --
Email: ales@apo
Country: United Kingdom
ProdList: 4521
Advantage: 58

Key Organics Ltd.

Tel: --
Fax: --
Email: enquiries@keyorganics.net
Country: United Kingdom
ProdList: 851
Advantage: 58

Manchester Organics

Tel: --
Fax: --
Email: info@manchesterorganics.com
Country: United Kingdom
ProdList: 6834
Advantage: 67

Biosynth Carbosynth

Tel: --
Fax: --
Email: ales@carbosynth.com
Country: United Kingdom
ProdList: 2598
Advantage: 58

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

Atlantic Research Chemicals Ltd.

Tel: --
Fax: --
Email: info@atlantic-chemicals.com
Country: United Kingdom
ProdList: 5618
Advantage: 63

Apin Chemicals Limited (UK)

Tel: --
Fax: --
Email: info@apinchemicals.com
Country: United Kingdom
ProdList: 6184
Advantage: 60

Key Organics Limited/Bionet Research

Tel: --
Fax: --
Email: enquiries@keyorganics.ltd.uk
Country: United Kingdom
ProdList: 6663
Advantage: 50

Leancare Ltd.

Tel: --
Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

CARBONE SCIENTIFIC CO.,LTD

Tel: --
Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

ETA SCIENTIFIC Co.,Ltd

Tel: --
Fax: --
Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
Advantage: 34

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Fluorochem Ltd

Tel: --
Fax: --
Email: vernam@fluorochem.co.uk
Country: United Kingdom
ProdList: 6375
Advantage: 65

Eurolabs Limited

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6309
Advantage: 46

Butt Park Ltd.

Tel: --
Fax: --
Email: 113707.50@compuserve.com
Country: United Kingdom
ProdList: 6078
Advantage: 30

Apin Chemicals Ltd.

Tel: --
Fax: --
Email: info@apinchemicals.com
Country: United Kingdom
ProdList: 6807
Advantage: 42

Ubichem plc

Tel: --
Fax: --
Email: sales@ubichem.com
Country: United Kingdom
ProdList: 1567
Advantage: 65

Fulcrum Scientific Ltd.

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6565
Advantage: 38

More

Less

View Lastest Price from 2-Amino-3-fluorobenzoic acid manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 2-amino-3-fluorobenzoic acid 825-22-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-08-19

Shaanxi Didu New Materials Co. Ltd

Product: 2-Amino-3-fluorobenzoic acid 825-22-9
Price: US $1.50/g
Min. Order: 1g
Purity: 99.0% Min
Supply Ability: 10 Tons
Release date: 2025-06-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Amino-3-fluorobenzoic acid 825-22-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-12

825-22-9, 2-Amino-3-fluorobenzoic acidRelated Search:

4-Aminobenzoic acid Urethane Methyl anthranilate POLYURETHANE Glycine ALTRENOGEST 2-AMINO-6-FLUOROBENZOIC ACID (6-FLUOROANTHRANILIC ACID),2-Amino-6-fluorobenzoic acid, 98% (6-Fluoroanthranilic acid),2-Amino-6-fluorobenzoic acid 97% Anthranilic acid 2-AMINO-4-FLUOROBENZOIC ACID,2-AMINO-4-FLUOROBENZOIC ACID / 4-FLUOROANTHRANILIC ACID,2-Amino-4-Fluorobenzoic Acid 99% 3-Amino-4-fluorobenzoic acid hydrochloride 97% 2-Amino-5-fluorobenzoic acid Methyl 2-amino-5-fluorobenzoate/ 2-Amino-5-fluorobenzoic acid methyl ester 3-Amino-4-fluorobenzoic acid 3-Amino-2-fluorobenzoic acid Ethyl 3-amino-4-fluorobenzoate 4-Amino-2-Fluorobenzoic Acid 2-Fluoro-4-Aminobenzoic Acid 5-Amino-2-fluorobenzoic acid 97% FMOC-2-AMINO-5-FLUOROBENZOIC ACID

BUTTPARK 22\01-93

2-AMINO-3-FLUOROBENZENECARBOXYLIC ACID

2-AMINO-3-FLUOROBENZOIC ACID

3-FLUOROANTHRANILIC ACID

2-AMINO-3-FLUOROBENZOIC

2-Amino-3-Fluoride Benzoic Acids

Benzoic acid, 2-amino-3-fluoro-

3-Fluoroanthranilic acid, 2-Carboxy-6-fluoroaniline

Diaphonic acid

2-AMino-3-fluorobenz

3-FluoroanthranilicAcid&gt

uorobenzenecarboxyL

2-Amino-3-fluorobenzoicAci

825-22-9

825-22-5

Fluorin-contained Benzoic acid series

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Fluorine series