ChemicalBook > CAS DataBase List > AC-LEHD-AFC

AC-LEHD-AFC

Product Name
AC-LEHD-AFC
CAS No.
210345-03-2
Chemical Name
AC-LEHD-AFC
Synonyms
AC-LEHD-AFC;Ac-LEHD-AFC TFA salt;AC-LEU-GLU-HIS-ASP-AFC;CASPASE-9 SUBSTRATE I, FLUOROGENIC;CASPASE 9 SUBSTRATE 1F, FLUOROGENIC;AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)
CBNumber
CB6377625
Molecular Formula
C33H38F3N7O11
Formula Weight
765.69
MOL File
210345-03-2.mol
More
Less

AC-LEHD-AFC Property

Boiling point:
1211.9±65.0 °C(Predicted)
Density 
1.457±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO/DMF: 20 mM
form 
powder
pka
4.07±0.10(Predicted)
color 
white
Water Solubility 
Soluble to 1 mg/ml in water
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
218765
Product name
Caspase-9 Substrate I, Fluorogenic
Purity
A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6).
Packaging
1MG
Price
$155
Updated
2024/03/01
Sigma-Aldrich
Product number
218765
Product name
Caspase-9 Substrate I, Fluorogenic
Purity
A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6).
Packaging
5MG
Price
$425
Updated
2024/03/01
Cayman Chemical
Product number
17051
Product name
Ac-LEHD-AFC
Purity
≥95%
Packaging
5mg
Price
$120
Updated
2021/12/16
Cayman Chemical
Product number
17051
Product name
Ac-LEHD-AFC
Purity
≥95%
Packaging
1mg
Price
$40
Updated
2021/12/16
Cayman Chemical
Product number
17051
Product name
Ac-LEHD-AFC
Purity
≥95%
Packaging
10mg
Price
$220
Updated
2021/12/16
More
Less

AC-LEHD-AFC Chemical Properties,Usage,Production

Uses

Ac-LEHD-AFC Trifluoroacetic Acid Salt is a fluorogenic substrate that is cleaved by caspases (4,5 and 9). This activity is quantified by fluorescent detection of free AFC. Caspase-9 activation is critical for intrinsic cell death.

Biological Activity

Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.

AC-LEHD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

AC-LEHD-AFC Suppliers

China 61 Germany 1 Japan 1 Switzerland 2 United Kingdom 2 United States 14 Global 81
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7312
Advantage
58
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9980
Advantage
55
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7071
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30233
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 18108052721
Email
2850505130@qq.com
Country
China
ProdList
5173
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Nanchang Tianzhen Biotechnology Co., Ltd
Tel
13173652190
Email
pomy@tanzhenbio.com
Country
China
ProdList
1895
Advantage
58
Nanjing TGpeptide Biotechnology Co.,Ltd.
Tel
18115476705
Email
sales@tgpeptide.com
Country
China
ProdList
3058
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
2891
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44807
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
DONBOO AMINO ACID COMPANY
Tel
+8613063595538
Email
donboo@donboo.com
Country
China
ProdList
9363
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24998
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-88211921 15572296305
Email
sales4@gotopbio.com
Country
China
ProdList
5178
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6628
Advantage
58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd.
Tel
0571-85350119 15888826472
Email
15888826472@163.com
Country
China
ProdList
2729
Advantage
58
Shanghai HongTide Biotechnology Co.,Ltd.
Tel
19961912513
Email
sales@hongtide.com
Country
China
ProdList
4604
Advantage
58
Combio (Suzhou) Ltd.
Tel
0512-51886999 17706251929
Email
office@combiosz.com
Country
China
ProdList
2978
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29979
Advantage
58
Shanghai Toyang Biotechnology Co., LTD
Tel
021-59555769 13524932310
Fax
021-50342869
Email
1405894150@qq.com
Country
China
ProdList
8221
Advantage
58
Nanjing Yushengkang Biotechnology Co., Ltd
Tel
13327808530
Email
2670965693@qq.com
Country
China
ProdList
2179
Advantage
58
Zhejiang Jiekun Biotechnology Co., Ltd
Tel
0571-88211951 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
4904
Advantage
58
Wuhan Peptide Core Biotechnology Co., Ltd
Tel
027-65317797 13667154760
Email
1096814016@qq.com
Country
China
ProdList
10020
Advantage
58
Taiyuan Bailihengkang Biotechnology Co., Ltd
Tel
19135651983 19135651983
Email
18611134419@163.com
Country
China
ProdList
4416
Advantage
58
Hangzhou Beiputai Biopharmaceutical Co., Ltd
Tel
0571-85350119 15888826472
Email
bptsales@163.com
Country
China
ProdList
3851
Advantage
58
Changsha MOL Changes Biotechnology Co., Ltd.
Tel
+8619375158599
Email
info@molchanges.com
Country
China
ProdList
5223
Advantage
58
Shenzhen Nexconn Pharmatechs Ltd
Tel
+86-755-89396905 +86-15013857715
Email
admin@nexconn.com
Country
China
ProdList
10311
Advantage
58
Zhejiang Hangyu API Co., Ltd
Tel
+8617531972939
Email
anna@api-made.com
Country
China
ProdList
2943
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
Nanjing TGpeptide
Tel
+86-13347807150 +86-13347807150
Email
support@tgpeptide.com
Country
China
ProdList
3279
Advantage
58
Chengdu Youngshe Chemical Co., Ltd.
Tel
+8618108235634
Email
Cecilia@youngshechem.com
Country
China
ProdList
2345
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6705
Advantage
58
Shanghai Gantu Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
1920192055@qq.com
Country
CHINA
ProdList
1843
Advantage
58
Shanghai Chaoyan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
471161314@qq.com
Country
CHINA
ProdList
6210
Advantage
58
Beijing Shengke Boyuan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
978560024@qq.com
Country
CHINA
ProdList
6005
Advantage
58
Shanghai Yaoyun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
912529879@qq.com
Country
CHINA
ProdList
6835
Advantage
58
Shenzhen Xinbosheng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
service@neobioscience.com
Country
CHINA
ProdList
6151
Advantage
58
Shanghai Haoran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
470003480@QQ.COM
Country
CHINA
ProdList
6955
Advantage
58
Shanghai Yijie Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
SHYIJIEBIO@126.COM
Country
CHINA
ProdList
3510
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6025
Advantage
58
Shenzhen Haodi Huatuo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
lm0210@otwobiotech.com
Country
CHINA
ProdList
6435
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6184
Advantage
58
Beijing Taize Jiaye Technology Development Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6050
Advantage
58

210345-03-2, AC-LEHD-AFCRelated Search:

Z-PHE-DL-ALA-FLUOROMETHYLKETONE AC-YVAD-PNA CASPASE INHIBITOR3 AC-VEID-AMC Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE Z-YVAD-AFC ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL AC-VDVAD-CHO AC-DEVD-AFC PAC1 AC-DEVD-CHO AC-LEU-GLU-THR-ASP-AFC AC-VDVAD-PNA Z-VAD-FMK AC-LEU-GLU-HIS-ASP-AMC AC-LEHD-AFC

  • N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN
  • N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)
  • N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC
  • AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN
  • AC-LEU-GLU-HIS-ASP-AFC
  • AC-LEHD-AFC
  • CASPASE-9 SUBSTRATE I, FLUOROGENIC
  • CASPASE 9 SUBSTRATE 1F, FLUOROGENIC
  • L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)
  • 4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
  • Ac-LEHD-AFC TFA salt
  • 210345-03-2
  • C33H38F3N7O11
  • C33H38O11N7F3
  • Caspases/Apoptosis
  • peptide